Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease
2016 | journal article; research paper
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Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease
Burkhardt, D.; Bartosova, M.; Schaefer, B.; Grabe, N. ; Lahrmann, B.; Nasser, H. & Freise, C. et al. (2016)
PLoS One, 11(11) art. e0166050. DOI: https://doi.org/10.1371/journal.pone.0166050
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Details
- Authors
- Burkhardt, Dorothea; Bartosova, Maria; Schaefer, Betti; Grabe, Niels ; Lahrmann, Bernd; Nasser, Hamoud; Freise, Christian; Schneider, Axel; Lingnau, Anja; Degenhardt, Petra; Ranchin, Bruno; Sallay, Peter; Cerkauskiene, Rimante; Malina, Michal; Ariceta, Gema; Schmitt, Claus Peter; Querfeld, Uwe
- Abstract
- Endothelial dysfunction is an early manifestation of cardiovascular disease (CVD) and consistently observed in patients with chronic kidney disease (CKD). We hypothesized that CKD is associated with systemic damage to the microcirculation, preceding macrovascular pathology. To assess the degree of "uremic microangiopathy", we have measured microvascular density in biopsies of the omentum of children with CKD.
- Issue Date
- 2016
- Journal
- PLoS One
- eISSN
- 1932-6203
- Language
- English