An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry

2022 | journal article; research paper. A publication with affiliation to the University of Göttingen.

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​An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry​
Kabatas Glowacki, S.; Agüi-Gonzalez, P. ; Sograte-Idrissi, S.; Jähne, S. ; Opazo Davila, L. F. ; Phan, N. T. N.   & Rizzoli, S. O. ​ (2022) 
Chemical Communications,.​ DOI: https://doi.org/10.1039/D2CC02290G 

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Authors
Kabatas Glowacki, Selda; Agüi-Gonzalez, Paola ; Sograte-Idrissi, Shama; Jähne, Sebastian ; Opazo Davila, Luis Felipe ; Phan, Nhu T. N. ; Rizzoli, Silvio O. 
Abstract
We developed here an iodine-containing probe that can be used to identify the molecules of interest in secondary ion mass spectrometry (SIMS) by simple immunolabelling procedures. The immunolabelled iodine probe was readily combined with previously-developed SIMS probes carrying fluorine, to generate dual-channel SIMS data. This probe should provide a useful complement to the currently available SIMS probes, thus expanding the scope of this technology.
Issue Date
2022
Journal
Chemical Communications 
Project
EXC 2067: Multiscale Bioimaging 
SFB 1286: Quantitative Synaptologie 
SFB 1286 | A03: Dynamische Analyse der Remodellierung der extrazellulären Matrix (ECM) als Mechanismus der Synapsenorganisation und Plastizität 
Working Group
RG Rizzoli (Quantitative Synaptology in Space and Time) 
RG Phan 
ISSN
1359-7345
eISSN
1364-548X
Language
English
Sponsor
Deutsche Forschungsgemeinschaft https://doi.org/10.13039/501100001659
Volkswagen Foundation https://doi.org/10.13039/501100001663

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