Reduction of potentially inappropriate medication in the elderly: design of a cluster-randomised controlled trial in German primary care practices (RIME)

2020 | journal article; research paper. A publication with affiliation to the University of Göttingen.

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​Reduction of potentially inappropriate medication in the elderly: design of a cluster-randomised controlled trial in German primary care practices (RIME)​
Thiem, U.; Wilm, S.; Greiner, W.; Rudolf, H.; Trampisch, H.; Müller, C.   & Theile, G. et al.​ (2020) 
Therapeutic Advances in Drug Safety11.​ DOI: https://doi.org/10.1177/2042098620918459 

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Authors
Thiem, Ulrich; Wilm, Stefan; Greiner, Wolfgang; Rudolf, Henrik; Trampisch, Hans–Joachim; Müller, Christiane ; Theile, Gudrun; Thürmann, Petra A.
Abstract
Potentially inappropriate medication (PIM) is considered to have potentially more harmful than beneficial health effects in elderly patients. A German example for a PIM list is the PRISCUS list that has been available since 2010. PIMs are associated with an increased risk of hospitalisation and adverse health outcomes. Furthermore, drug-drug interactions (DDI) may pose additional risks to patients. It is not yet clear how numbers of PIM and DDI can be reduced in community-dwelling seniors in primary care; nor is it clear whether patients would benefit from such deprescribing.
Issue Date
2020
Journal
Therapeutic Advances in Drug Safety 
Organization
Institut für Allgemeinmedizin 
ISSN
2042-0986
eISSN
2042-0994
Language
English

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