DIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS
2010 | journal article. A publication with affiliation to the University of Göttingen.
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- Authors
- Subramanian, Amarendran R.; Hiran, Suvrat; Steinkamp, Rasmus; Meinicke, Peter ; Corel, Eduardo; Morgenstern, Burkhard
- Abstract
- We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional 'progressive' approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary sequence information to construct multiple protein alignments. Both programs are available through 'Gottingen Bioinformatics Compute Server' (GOBICS).
- Issue Date
- 2010
- Status
- published
- Publisher
- Oxford Univ Press
- Journal
- Nucleic Acids Research
- ISSN
- 0305-1048