Acute outcomes after MitraClip (R) therapy in highly aged patients: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) Registry
2013 | journal article. A publication with affiliation to the University of Göttingen.
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Acute outcomes after MitraClip (R) therapy in highly aged patients: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) Registry
Schillinger, W.; Huenlich, M.; Baldus, S.; Ouarrak, T.; Boekstegers, P.; Hink, U. & Butter, C. et al. (2013)
EuroIntervention, 9(1) pp. 84-90.
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- Authors
- Schillinger, Wolfgang; Huenlich, Mark; Baldus, Stephan; Ouarrak, Taoufik; Boekstegers, Peter; Hink, Ulrich; Butter, Christian; Bekeredjian, Raffi; Plicht, Bjoern; Sievert, Horst; Schofer, Joachim; Senges, Jochen; Meinertz, Thomas; Hasenfuß, Gerd
- Abstract
- Aims: The influence of age on baseline demographics and outcomes of patients selected for MitraClip (R) has not been previously investigated. Methods and results: Baseline demographics and acute outcomes in 1,064 patients from the German TRAMI registry were stratified by age (525 patients >= 76 years and 539 patients <76 years). In elderly patients, logistic EuroSCORE was higher (25[15-40]% vs. 18[10-31]%, p<0.0001) and the proportion of women was greater (47.2% vs. 29.3%, p<0.0001). Elderly patients were more likely to have preserved left ventricular ejection fraction >50% (40.1% vs. 21.8%, p<0.0001) and degenerative mitral regurgitation (DMR, 35.3% vs. 25.6%, p<0.01). Age was the most frequent reason for non-surgical treatment in the elderly (69.4% vs. 36.1%, p<0.0001). The intrahospital MACCE (death, myocardial infarction, stroke) was low in both groups (3.5% vs. 3.4%, p=0.93) and the proportion of non-severe mitral regurgitation at discharge was similar (95.8% vs. 96.4%, p=0.73). A logistic regression model did not reveal any significant impact of age on acute efficacy and safety of MitraClip therapy. In both groups, the majority of patients were discharged home (81.8% vs. 86.2%, p=0.06). Conclusions: Elderly and younger patients have similar benefits from MitraClip therapy. Age was the most frequent cause for denying surgery in elderly patients.
- Issue Date
- 2013
- Status
- published
- Publisher
- Europa Edition
- Journal
- EuroIntervention
- ISSN
- 1774-024X