Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening
2016 | journal article. A publication with affiliation to the University of Göttingen.
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Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening
van Oosten, A. S. G.; Vahabi, M.; Licup, A. J.; Sharma, A.; Galie, P. A.; MacKintosh, F. C. & Janmey, P. A. (2016)
Scientific Reports, 6 art. 19270. DOI: https://doi.org/10.1038/srep19270
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Details
- Authors
- van Oosten, Anne S. G.; Vahabi, Mahsa; Licup, Albert J.; Sharma, Abhinav; Galie, Peter A.; MacKintosh, Frederick C.; Janmey, Paul A.
- Abstract
- Gels formed by semiflexible filaments such as most biopolymers exhibit non-linear behavior in their response to shear deformation, e.g., with a pronounced strain stiffening and negative normal stress. These negative normal stresses suggest that networks would collapse axially when subject to shear stress. This coupling of axial and shear deformations can have particularly important consequences for extracellular matrices and collagenous tissues. Although measurements of uniaxial moduli have been made on biopolymer gels, these have not directly been related to the shear response. Here, we report measurements and simulations of axial and shear stresses exerted by a range of hydrogels subjected to simultaneous uniaxial and shear strains. These studies show that, in contrast to volume-conserving linearly elastic hydrogels, the Young's moduli of networks formed by the biopolymers are not proportional to their shear moduli and both shear and uniaxial moduli are strongly affected by even modest degrees of uniaxial strain.
- Issue Date
- 2016
- Status
- published
- Publisher
- Nature Publishing Group
- Journal
- Scientific Reports
- Organization
- Fakultät für Physik
- ISSN
- 2045-2322