Potential Involvement of Osteopontin in Inflammatory and Fibrotic Processes in Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension
2019 | journal article. A publication with affiliation to the University of Göttingen.
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Potential Involvement of Osteopontin in Inflammatory and Fibrotic Processes in Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension
Kölmel, S.; Hobohm, L.; Käberich, A.; Krieg, V. J.; Bochenek, M. L.; Wenzel, P. & Wiedenroth, C. B. et al. (2019)
Thrombosis and Haemostasis, 119(8) pp. 1332-1346. DOI: https://doi.org/10.1055/s-0039-1692174
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Details
- Authors
- Kölmel, Sebastian; Hobohm, Lukas; Käberich, Anja; Krieg, Valentin J.; Bochenek, Magdalena L.; Wenzel, Philip; Wiedenroth, Christoph B.; Liebetrau, Christoph; Hasenfuß, Gerd ; Mayer, Eckhard; Konstantinides, Stavros V.; Schäfer, Katrin ; Guth, Stefan; Lankeit, Mareike
- Abstract
- Inflammation and incomplete thrombus resolution leading to obstructive fibrotic remodelling are considered critical mechanisms for the development of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE). Osteopontin (OPN) is involved in a variety of biological processes including inflammation and tissue fibrosis.
- Issue Date
- 2019
- Journal
- Thrombosis and Haemostasis
- ISSN
- 0340-6245; 2567-689X
- eISSN
- 2567-689X
- Language
- English
