Nanoscopy in a Living Mouse Brain
2012 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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Details
- Authors
- Berning, Sebastian ; Willig, Katrin I. ; Steffens, Heinz ; Dibaj, Payam ; Hell, Stefan
- Abstract
- We demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in the cerebral cortex of a mouse with <70-nanometer resolution. Dendritic spines and their subtle changes can be observed at their relevant scales over extended periods of time.
- Issue Date
- 2012
- Journal
- Science
- ISSN
- 0036-8075
- Language
- English