PD Dr. rer. nat. Olaf Jahn

 
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  • 2022 Journal Article | Research Paper | 
    ​ ​White matter integrity in mice requires continuous myelin synthesis at the inner tongue​
    Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K. ; Jahn, O. ; Piepkorn, L. & Agüi-Gonzalez, P.  et al.​ (2022) 
    Nature Communications13(1) art. 1163​.​ DOI: https://doi.org/10.1038/s41467-022-28720-y 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples​
    Klafki, H. W. ; Rieper, P.; Matzen, A.; Zampar, S.; Wirths, O. ; Vogelgsang, J. & Osterloh, D. et al.​ (2020) 
    International Journal of Molecular Sciences21(18) pp. 6564​.​ DOI: https://doi.org/10.3390/ijms21186564 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients​
    Koziolek, M. ; Mueller, G. A.; Dihazi, G. H. ; Jung, K. ; Altubar, C.; Wallbach, M.   & Markovic, I. et al.​ (2020) 
    Journal of Clinical Medicine9(3) pp. 639​.​ DOI: https://doi.org/10.3390/jcm9030639 
    Details  DOI 
  • 2020 Journal Article
    ​ ​The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc​
    Ambrozkiewicz, M. C.; Borisova, E.; Schwark, M.; Ripamonti, S.; Schaub, T.; Smorodchenko, A. & Weber, A. I. et al.​ (2020) 
    Molecular Psychiatry,.​ DOI: https://doi.org/10.1038/s41380-020-0714-8 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Proteome profile of peripheral myelin in healthy mice and in a neuropathy model​
    Siems, S. B; Jahn, O. ; Eichel, M. A; Kannaiyan, N.; Wu, L. M. N; Sherman, D. L & Kusch, K.  et al.​ (2020) 
    eLife9.​ DOI: https://doi.org/10.7554/eLife.51406 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20​
    Ripamonti, S.; Shomroni, O. ; Rhee, J. S. ; Chowdhury, K.; Jahn, O. ; Hellmann, K. P. & Bonn, S.  et al.​ (2020) 
    Journal of Neurochemistry154(6) pp. 647​-661​.​ DOI: https://doi.org/10.1111/jnc.15008 
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  • 2020 Journal Article | Research Paper
    ​ ​The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay​
    Jahn, O. ; Siems, S. B.; Kusch, K.; Hesse, D.; Jung, R. B.; Liepold, T. & Uecker, M. et al.​ (2020) 
    Frontiers in Cellular Neuroscience14 pp. 239​.​ DOI: https://doi.org/10.3389/fncel.2020.00239 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​Delineating the Molecular Basis of the Calmodulin‒bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry-Evidence for a Novel CaM Binding Motif in bMunc13-2​
    Piotrowski, C.; Moretti, R.; Ihling, C. H.; Haedicke, A.; Liepold, T.; Lipstein, N. & Meiler, J. et al.​ (2020) 
    Cells9(1) pp. 136​.​ DOI: https://doi.org/10.3390/cells9010136 
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  • 2020 Journal Article | Research Paper | 
    ​ ​The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis​
    Dihazi, G. H.; Eltoweissy, M.; Jahn, O. ; Tampe, B.; Zeisberg, M. ; Wülfrath, H. S. & Müller, G. A. et al.​ (2020) 
    Cells9(7) pp. 1724​.​ DOI: https://doi.org/10.3390/cells9071724 
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  • 2019 Journal Article
    ​ ​Vti1b promotes TRPV1 sensitization during inflammatory pain​
    Sondermann, J. R.; Barry, A. M.; Jahn, O. ; Michel, N.; Abdelaziz, R.; Kügler, S.   & Gomez-Varela, D. et al.​ (2019) 
    Pain160(2) pp. 508​-527​.​ DOI: https://doi.org/10.1097/j.pain.0000000000001418 
    Details  DOI 
  • 2019 Journal Article
    ​ ​N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo​
    Hornung, K.; Zampar, S.; Engel, N.; Klafki, H. ; Liepold, T. ; Bayer, T. A.   & Wiltfang, J.  et al.​ (2019) 
    Journal of Alzheimer's Disease67(3) pp. 849​-858​.​ DOI: https://doi.org/10.3233/JAD-181134 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix​
    Scholz, N.; Ehmann, N.; Sachidanandan, D.; Imig, C.; Cooper, B. H. ; Jahn, O.   & Reim, K. et al.​ (2019) 
    The Journal of Cell Biology218(3) pp. 1011​-1026​.​ DOI: https://doi.org/10.1083/jcb.201806155 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting​
    Akula, A. K.; Zhang, X.; Viotti, J. S.; Nestvogel, D.; Rhee, J.-S. ; Ebrecht, R. & Reim, K. et al.​ (2019) 
    Frontiers in Molecular Neuroscience12.​ DOI: https://doi.org/10.3389/fnmol.2019.00249 
    Details  DOI 
  • 2019 Conference Paper | 
    ​ ​Mapping Cellular Microenvironments: Proximity Labeling and Complexome Profiling​
    Beißbarth, T. ; Bohrer, R.; Feussner, K.; Jahn, O. ; Schmitt, K.; Valerius, O. & Asif, A. R. et al.​ (2019)
    Cells8(10) p. 1192. ​Seventh Symposium of the Göttingen Proteomics Forum​, Göttingen.
    MDPI. DOI: https://doi.org/10.3390/cells8101192 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies​
    Szegő, É. M.; Dominguez-Meijide, A.; Gerhardt, E.; König, A.; Koss, D. J.; Li, W. & Pinho, R. et al.​ (2019) 
    Cell Reports28(1) pp. 65.e6​-77.e6​.​ DOI: https://doi.org/10.1016/j.celrep.2019.06.009 
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  • 2019 Journal Article | 
    ​ ​Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release​
    López-Murcia, F. J.; Reim, K.; Jahn, O. ; Taschenberger, H. & Brose, N. ​ (2019) 
    Cell Reports26(10) art. 2530.e5​.​ DOI: https://doi.org/10.1016/j.celrep.2019.02.030 
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  • 2019 Journal Article | 
    ​ ​Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin​
    Erwig, M. S.; Patzig, J. ; Steyer, A. M.; Dibaj, P. ; Heilmann, M.; Heilmann, I.   & Jung, R. B. et al.​ (2019) 
    eLife8.​ DOI: https://doi.org/10.7554/eLife.43888 
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  • 2019 Journal Article | Research Paper
    ​ ​Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy​
    Joseph, S.; Vingill, S.; Jahn, O. ; Fledrich, R.; Werner, H. B.; Katona, I. & Möbius, W.  et al.​ (2019) 
    The Journal of Neuroscience39(28) pp. 5606​-5626​.​ DOI: https://doi.org/10.1523/JNEUROSCI.3094-18.2019 
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  • 2018 Journal Article
    ​ ​Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140​
    Ambrozkiewicz, M. C.; Schwark, M.; Kishimoto-Suga, M.; Borisova, E.; Hori, K.; Salazar-Lázaro, A. & Rusanova, A. et al.​ (2018) 
    Neuron100(5) pp. 1097​-1115.e15​.​ DOI: https://doi.org/10.1016/j.neuron.2018.10.008 
    Details  DOI 
  • 2018 Journal Article | Research Paper
    ​ ​Integrative omics - from data to biology​
    Dihazi, H.; Asif, A. R; Beißbarth, T. ; Bohrer, R.; Feussner, K.; Feussner, I. & Jahn, O.  et al.​ (2018) 
    Expert Review of Proteomics15(6) pp. 463​-466​.​ DOI: https://doi.org/10.1080/14789450.2018.1476143 
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  • 2018 Journal Article | Research Paper | 
    ​ ​SUMO1-conjugation is altered during normal aging but not by increased amyloid burden​
    Stankova, T.; Piepkorn, L.; Bayer, T. A. ; Jahn, O.   & Tirard, M.​ (2018) 
    Aging Cell17(4) pp. e12760​.​ DOI: https://doi.org/10.1111/acel.12760 
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  • 2017 Journal Article | 
    ​ ​Differential regulation of synaptic AP-2/clathrin vesicle uncoating in synaptic plasticity.​
    Candiello, E.; Mishra, R.; Schmidt, B.; Jahn, O.   & Schu, P.​ (2017) 
    Scientific Reports7(1) art. 15781​.​ DOI: https://doi.org/10.1038/s41598-017-16055-4 
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  • 2017 Journal Article
    ​ ​Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder​
    Lipstein, N.; Verhoeven-Duif, N. M.; Michelassi, F. E.; Calloway, N.; van Hasselt, P. M.; Pienkowska, K. & van Haaften, G. et al.​ (2017) 
    The Journal of Clinical Investigation127(3) pp. 1005​-1018​.​ DOI: https://doi.org/10.1172/JCI90259 
    Details  DOI 
  • 2017 Conference Abstract
    ​ ​SIRT2 as a genetic modifier of axonal degeneration in white matter tracts​
    Kusch, K. ; Uecker, M. ; Liepold, T. ; Möbius, W. ; Werner, H. B. ; Valerius, O.   & Jahn, O.  et al.​ (2017)
    Glia65 ​13th European Meeting on Glial Cells in Health and Disease​, Edinburgh, Scotland.
    Hoboken​: Wiley.
    Details  WoS 
  • 2017 Journal Article | 
    ​ ​Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome​
    Kusch, K. ; Uecker, M.; Liepold, T. ; Möbius, W. ; Hoffmann, C.; Neumann, H.   & Werner, H.  et al.​ (2017) 
    Proteomes5(4) pp. 3​.​ DOI: https://doi.org/10.3390/proteomes5010003 
    Details  DOI 
  • 2017 Journal Article | Research Paper
    ​ ​Presynaptic Calmodulin targets: lessons from structural proteomics​
    Lipstein, N.; Göth, M.; Piotrowski, C.; Pagel, K.; Sinz, A. & Jahn, O. ​ (2017) 
    Expert Review of Proteomics14(3) pp. 223​-242​.​ DOI: https://doi.org/10.1080/14789450.2017.1275966 
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  • 2016 Journal Article | 
    ​ ​Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ−3-x-Peptides​
    Beyer, I.; Rezaei-Ghaleh, N. ; Klafki, H.-W. ; Jahn, O. ; Haußmann, U.; Wiltfang, J.   & Zweckstetter, M.  et al.​ (2016) 
    Chemistry - A European Journal22(25) pp. 8685​-8693​.​ DOI: https://doi.org/10.1002/chem.201600892 
    Details  DOI 
  • 2016 Journal Article | Research Paper | 
    ​ ​The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code​
    Hofhuis, J. ; Schueren, F. ; Nötzel, C.; Lingner, T.; Gärtner, J. ; Jahn, O.   & Thoms, S. ​ (2016) 
    Open Biology6(11) art. 160246​.​ DOI: https://doi.org/10.1098/rsob.160246 
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  • 2015 Journal Article | Research Paper
    ​ ​Protein corona of nanoparticles: distinct proteins regulate the cellular uptake​
    Ritz, S.; Schöttler, S.; Kotman, N.; Baier, G.; Musyanovych, A.; Kuharev, J. & Landfester, K. et al.​ (2015) 
    Biomacromolecules16(4) pp. 1311​-1321​.​ DOI: https://doi.org/10.1021/acs.biomac.5b00108 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Erratum | 
    ​ ​Erratum to: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury​
    Ott, C.; Martens, H.; Hassouna, I.; Oliveira, B.; Erck, C.; Zafeiriou, M.-P. & Peteri, U.-K. et al.​ (2015) 
    Molecular Medicine21(1) pp. 816​-816​.​ DOI: https://doi.org/10.2119/molmed.2015.00192.erratum 
    Details  DOI 
  • 2015 Journal Article | Research Paper | 
    ​ ​Widespread expression of erythropoietin receptor in brain and its induction by injury​
    Ott, C. ; Martens, H.; Hassouna, I. ; Oliveira, B. ; Erck, C.; Zafiriou, M. P.   & Peteri, U.-K.  et al.​ (2015) 
    Molecular Medicine21(1) pp. 803​-815​.​ DOI: https://doi.org/10.2119/molmed.2015.00192 
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  • 2015 Journal Article
    ​ ​AP-1/sigma 1B-Dependent SV Protein Recycling Is Regulated in Early Endosomes and Is Coupled to AP-2 Endocytosis​
    Kratzke, M.; Candiello, E. ; Schmidt, B.; Jahn, O.   & Schu, P.​ (2015) 
    Molecular Neurobiology52(1) pp. 142​-161​.​ DOI: https://doi.org/10.1007/s12035-014-8852-0 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Proteomic analysis of embryonic kidney development: Heterochromatin proteins as epigenetic regulators of nephrogenesis​
    Dihazi, G. H.; Jahn, O. ; Tampe, B.; Zeisberg, M. ; Mueller, C.; Mueller, G. A. & Dihazi, H.​ (2015) 
    Scientific Reports5 art. 13951​.​ DOI: https://doi.org/10.1038/srep13951 
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  • 2015 Journal Article | Research Paper
    ​ ​A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria​
    Melin, J. ; Kilisch, M. ; Neumann, P. ; Lytovchenko, O. ; Gomkale, R.; Schendzielorz, A. B.   & Schmidt, B.  et al.​ (2015) 
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research1853(8) pp. 1850​-1859​.​ DOI: https://doi.org/10.1016/j.bbamcr.2015.04.021 
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  • 2015 Journal Article | 
    ​ ​Haptoglobin-alpha 1, -alpha 2, vitamin D-binding protein and apolipoprotein C-III as predictors of etanercept drug response in rheumatoid arthritis​
    Blaschke, S.; Rinke, K.; Maring, M.; Flad, T.; Patschan, S. A.; Jahn, O.   & Mueller, C. A. et al.​ (2015) 
    Arthritis Research & Therapy17 art. 45​.​ DOI: https://doi.org/10.1186/s13075-015-0553-1 
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  • 2015 Journal Article | 
    ​ ​Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157​
    Matz, A.; Lee, S. J.; Schwedhelm-Domeyer, N.; Zanini, D.; Holubowska, A.; Kannan, M. & Farnworth, M. S. et al.​ (2015) 
    Cell Death and Differentiation22(4) pp. 626​-642​.​ DOI: https://doi.org/10.1038/cdd.2014.163 
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  • 2014 Journal Article | Research Paper
    ​ ​Reliable identification of cross-linked products in protein interaction studies by 13C-labeled p-benzoylphenylalanine​
    Pettelkau, J.; Ihling, C. H.; Frohberg, P.; van Werven, L.; Jahn, O.   & Sinz, A.​ (2014) 
    Journal of the American Society for Mass Spectrometry25(9) pp. 1628​-1641​.​ DOI: https://doi.org/10.1007/s13361-014-0944-6 
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  • 2014 Journal Article | Research Paper
    ​ ​Structural insights into calmodulin/Munc13 interaction​
    Herbst, S.; Lipstein, N.; Jahn, O.   & Sinz, A.​ (2014) 
    Biological Chemistry395(7-8) pp. 763​-768​.​ DOI: https://doi.org/10.1515/hsz-2014-0134 
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  • 2014 Journal Article | Research Paper
    ​ ​TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein​
    Heurich, A.; Hofmann-Winkler, H.; Gierer, S.; Liepold, T.; Jahn, O.   & Pöhlmann, S.​ (2014) 
    Journal of Virology88(2) pp. 1293​-1307​.​ DOI: https://doi.org/10.1128/JVI.02202-13 
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  • 2014 Journal Article | Research Paper
    ​ ​B32 Alterations in Mitochondrial Proteome of Brain and Skeletal Muscle in Two Transgenic HD Mouse Models do not Reflect Mitochondrial Respiratory Activity​
    Barth, E.; Fleischer, C.; Lenk, T.; Lehnert, S.; Jahn, O. ; Otto, M. & Calzia, E. et al.​ (2014) 
    Journal of Neurology, Neurosurgery & Psychiatry85(Suppl. 1) pp. A20​-A20​.​ DOI: https://doi.org/10.1136/jnnp-2014-309032.60 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells​
    Buhl, T.; Braun, A.; Forkel, S.; Möbius, W. ; van Werven, L.; Jahn, O.   & Rezaei-Ghaleh, N. et al.​ (2014) 
    Experimental Dermatology23(1) pp. 20​-26​.​ DOI: https://doi.org/10.1111/exd.12285 
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  • 2014 Conference Abstract
    ​ ​Routes of internalization for Melan-A/TAT fusion peptides differ considerably between human dendritic cells and other non-phagocytic cell types​
    Buhl, T.; Braun, A.; Forkel, S.; Möbius, W. ; van Werven, L.; Jahn, O.   & Rezaei-Ghaleh, N. et al.​ (2014)
    Experimental Dermatology23(3) , Cologne, GERMANY.
    Hoboken​: Wiley-blackwell.
    Details  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Presequence Recognition by the Tom40 Channel Contributes to Precursor Translocation into the Mitochondrial Matrix​
    Melin, J. ; Schulz, C. ; Wrobel, L.; Bernhard, O. ; Chacinska, A.; Jahn, O.   & Schmidt, B.  et al.​ (2014) 
    Molecular and Cellular Biology34(18) pp. 3473​-3485​.​ DOI: https://doi.org/10.1128/MCB.00433-14 
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  • 2014 Journal Article | Research Paper
    ​ ​Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting​
    Biesemann, C.; Grønborg, M.; Luquet, E.; Wichert, S. P; Bernard, V.; Bungers, S. R & Cooper, B.  et al.​ (2014) 
    EMBO Journal33(2) pp. 157​-170​.​ DOI: https://doi.org/10.1002/embj.201386120 
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  • 2013 Journal Article | Research Paper
    ​ ​Analysis of amino-terminal variants of amyloid-β peptides by capillary isoelectric focusing immunoassay​
    Haußmann, U.; Jahn, O. ; Linning, P.; Janßen, C.; Liepold, T.; Portelius, E. & Zetterberg, H. et al.​ (2013) 
    Analytical Chemistry85(17) pp. 8142​-8149​.​ DOI: https://doi.org/10.1021/ac401055y 
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  • 2013 Journal Article | Research Paper
    ​ ​Molecular evolution of myelin basic protein, an abundant structural myelin component​
    Nawaz, S.; Schweitzer, J.; Jahn, O.   & Werner, H. B.​ (2013) 
    Glia61(8) pp. 1364​-1377​.​ DOI: https://doi.org/10.1002/glia.22520 
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  • 2013 Journal Article | 
    ​ ​Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome.​
    Dihazi, G. H.; Bibi, A.; Jahn, O. ; Nolte, J.; Mueller, G. A.; Engel, W. & Dihazi, H.​ (2013) 
    World Journal of Stem Cells5(1) pp. 9​-25​.​ DOI: https://doi.org/10.4252/wjsc.v5.i1.9 
    Details  DOI  PMID  PMC 
  • 2013 Journal Article | Research Paper
    ​ ​Munc13-like skMLCK variants cannot mimic the unique calmodulin binding mode of Munc13 as evidenced by chemical cross-linking and mass spectrometry​
    Herbst, S.; Maucher, D.; Schneider, M.; Ihling, C. H.; Jahn, O.   & Sinz, A.​ (2013) 
    PLoS One8(10) art. e75119​.​ DOI: https://doi.org/10.1371/journal.pone.0075119 
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  • 2013 Journal Article
    ​ ​An automated in-gel digestion/iTRAQ-labeling workflow for robust quantification of gel-separated proteins​
    Schmidt, C.; Hesse, D.; Raabe, M.; Urlaub, H. & Jahn, O. ​ (2013) 
    Proteomics13(9) pp. 1417​-1422​.​ DOI: https://doi.org/10.1002/pmic.201200366 
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  • 2013 Journal Article | 
    ​ ​NumbL is essential for Xenopus primary neurogenesis​
    Nieber, F.; Hedderich, M.; Jahn, O. ; Pieler, T. & Henningfeld, K. A.​ (2013) 
    BMC Developmental Biology13 art. 36​.​ DOI: https://doi.org/10.1186/1471-213X-13-36 
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  • 2012 Journal Article | Research Paper
    ​ ​Systematic approaches to central nervous system myelin​
    de Monasterio-Schrader, P.; Jahn, O. ; Tenzer, S.; Wichert, S. P.; Patzig, J. & Werner, H. B.​ (2012) 
    Cellular and Molecular Life Sciences69(17) pp. 2879​-2894​.​ DOI: https://doi.org/10.1007/s00018-012-0958-9 
    Details  DOI  PMID  PMC 
  • 2012 Journal Article | Research Paper
    ​ ​Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS​
    Otto, M.; Bowser, R.; Turner, M.; Berry, J.; Brettschneider, J.; Connor, J. & Costa, J. et al.​ (2012) 
    Amyotrophic Lateral Sclerosis13(1) pp. 1​-10​.​ DOI: https://doi.org/10.3109/17482968.2011.627589 
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  • 2012 Journal Article | Research Paper
    ​ ​Nonconserved Ca²⁺/Calmodulin Binding Sites in Munc13s Differentially Control Synaptic Short-Term Plasticity​
    Lipstein, N.; Schaks, S.; Dimova, K.; Kalkhof, S.; Ihling, C.; Kölbel, K. & Ashery, U. et al.​ (2012) 
    Molecular and Cellular Biology32(22) pp. 4628​-4641​.​ DOI: https://doi.org/10.1128/MCB.00933-12 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease​
    Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al.​ (2011) 
    Journal of Virology85(24) pp. 13363​-13372​.​ DOI: https://doi.org/10.1128/JVI.05300-11 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article | Research Paper
    ​ ​Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci​
    Patzig, J.; Jahn, O. ; Tenzer, S.; Wichert, S. P.; de Monasterio-Schrader, P.; Rosfa, S. & Kuharev, J. et al.​ (2011) 
    The Journal of Neuroscience31(45) pp. 16369​-16386​.​ DOI: https://doi.org/10.1523/JNEUROSCI.4016-11.2011 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article | Research Paper
    ​ ​Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid​
    Schieb, H.; Kratzin, H.; Jahn, O. ; Möbius, W. ; Rabe, S.; Staufenbiel, M. & Wiltfang, J. et al.​ (2011) 
    The Journal of Biological Chemistry286(39) pp. 33747​-33758​.​ DOI: https://doi.org/10.1074/jbc.M111.246561 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article
    ​ ​Prediction of the risk of comorbid alcoholism in schizophrenia by interaction of common genetic variants in the corticotropin-releasing factor system​
    Ribbe, K. ; Ackermann, V.; Schwitulla, J.; Begemann, M. ; Papiol, S. ; Grube, S. & Sperling, S.  et al.​ (2011) 
    Archives of General Psychiatry68(12) pp. 1247​-1256​.​ DOI: https://doi.org/10.1001/archgenpsychiatry.2011.100 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Apolipoprotein A-I as a candidate serum marker for the response to lithium treatment in bipolar disorder​
    Sussulini, A. ; Dihazi, H. ; Muller Banzato, C. E.; Zezzi Arruda, M. A.; Stühmer, W. ; Ehrenreich, H.   & Jahn, O.  et al.​ (2011) 
    Proteomics,(2) pp. 261​-269​.​ DOI: https://doi.org/10.1002/pmic.201000371 
    Details  DOI 
  • 2011 Journal Article
    ​ ​New Molecular Markers for Prostate Tumor Imaging: A Study on 2-Methylene Substituted Fatty Acids as New AMACR Inhibitors​
    Morgenroth, A.; Urusova, E. A.; Dinger, C.; Al-Momani, E.; Kull, T.; Glatting, G. & Frauendorf, H. et al.​ (2011) 
    Chemistry - A European Journal17(36) pp. 10144​-10150​.​ DOI: https://doi.org/10.1002/chem.201003176 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex​
    Schulz, C. ; Lytovchenko, O. ; Melin, J. ; Chacinska, A.; Guiard, B.; Neumann, P.   & Ficner, R.  et al.​ (2011) 
    The Journal of Cell Biology195(4) pp. 643​-656​.​ DOI: https://doi.org/10.1083/jcb.201105098 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Multipotent Adult Germline Stem Cells and Embryonic Stem Cells Functional Proteomics Revealed an Important Role of Eukaryotic Initiation Factor 5A (Eif5a) in Stem Cell Differentiation​
    Dihazi, H.; Dihazi, G. H.; Jahn, O. ; Meyer, S.; Nolte, J.; Asif, A. R. & Mueller, G. A. et al.​ (2011) 
    Journal of Proteome Research10(4) pp. 1962​-1973​.​ DOI: https://doi.org/10.1021/pr1012015 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Identification and validation of six proteins as marker for endemic nephropathy​
    Pesic, I.; Stefanovic, V.; Mueller, G. A.; Mueller, C. A.; Cukuranovic, R.; Jahn, O.   & Bojanic, V. et al.​ (2011) 
    Journal of Proteomics74(10) pp. 1994​-2007​.​ DOI: https://doi.org/10.1016/j.jprot.2011.05.020 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Long- Term Intrathecal Infusion of Outer Surface Protein C From Borrelia burgdorferi Causes Axonal Damage​
    Tauber, S. C.; Ribes, S.; Ebert, S.; Heinz, T.; Fingerle, V.; Bunkowski, S. & Kugelstadt, D. et al.​ (2011) 
    Journal of Neuropathology and Experimental Neurology70(9) pp. 748​-757​.​ DOI: https://doi.org/10.1097/NEN.0b013e3182289acd 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Metallomics studies of human blood serum from treated bipolar disorder patients​
    Sussulini, A.; Kratzin, H.; Jahn, O. ; Muller Banzato, C. E.; Zezzi Arruda, M. A. & Becker, J. S.​ (2010) 
    Analytical Chemistry82(13) pp. 5859​-5864​.​ DOI: https://doi.org/10.1021/ac101063t 
    Details  DOI  PMID  PMC 
  • 2010 Journal Article | Research Paper
    ​ ​Myelin matters: proteomic insights into white matter disorders​
    Werner, H. B. & Jahn, O. ​ (2010) 
    Expert Review of Proteomics7(2) pp. 159​-164​.​ DOI: https://doi.org/10.1586/epr.09.105 
    Details  DOI  PMID  PMC 
  • 2010 Journal Article | Research Paper
    ​ ​Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis​
    Steinacker, P.; Hawlik, A.; Lehnert, S.; Jahn, O. ; Meier, S.; Görz, E. & Braunstein, K. E. et al.​ (2010) 
    The American Journal of Pathology176(3) pp. 1409​-1420​.​ DOI: https://doi.org/10.2353/ajpath.2010.090355 
    Details  DOI  PMID  PMC 
  • 2010 Journal Article | Research Paper
    ​ ​A12 Mitochondrial proteome analysis of R6/2 mouse brains​
    Fleischer, C.; Lehnert, S.; Jahn, O. ; Otto, M.; Landwehrmeyer, G. B. & Lindenberg, K. S.​ (2010) 
    Journal of Neurology, Neurosurgery & Psychiatry81(Suppl. 1) pp. A4.2​-A4​.​ DOI: https://doi.org/10.1136/jnnp.2010.222570.12 
    Details  DOI 
  • 2010 Journal Article | Research Paper
    ​ ​SNARE Protein Recycling by alpha SNAP and beta SNAP Supports Synaptic Vesicle Priming​
    Burgalossi, A.; Jung, S. ; Meyer, G.; Jockusch, W. J.; Jahn, O. ; Taschenberger, H. & O'Connor, V. M. et al.​ (2010) 
    Neuron68(3) pp. 473​-487​.​ DOI: https://doi.org/10.1016/j.neuron.2010.09.019 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development​
    Kawabe, H.; Neeb, A.; Dimova, K.; Young, S. M. J.; Takeda, M.; Katsurabayashi, S. & Mitkovski, M. et al.​ (2010) 
    Neuron65(3) pp. 358​-372​.​ DOI: https://doi.org/10.1016/j.neuron.2010.01.007 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​A Proteomic Approach for the Diagnosis of Bacterial Meningitis​
    Jesse, S.; Steinacker, P.; Lehnert, S.; Sdzuj, M.; Cepek, L.; Tumani, H. & Jahn, O.  et al.​ (2010) 
    PLoS One5(4) art. e10079​.​ DOI: https://doi.org/10.1371/journal.pone.0010079 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca²⁺ and possible function in short-term synaptic plasticity​
    Rodriguez-Castaneda, F.; Maestre-Martinez, M.; Coudevylle, N.; Dimova, K.; Junge, H. J.; Lipstein, N. & Lee, D.  et al.​ (2010) 
    EMBO Journal29(3) pp. 680​-691​.​ DOI: https://doi.org/10.1038/emboj.2009.373 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​Urocortin and corticotropin-releasing factor receptor 2 in human renal cell carcinoma: disruption of an endogenous inhibitor of angiogenesis and proliferation​
    Tezval, H.; Jurk, S.; Atschekzei, F.; Becker, J. U.; Jahn, O. ; Serth, J. & Kuczyk, M. A.​ (2009) 
    World Journal of Urology27(6) pp. 825​-830​.​ DOI: https://doi.org/10.1007/s00345-009-0417-x 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article | 
    ​ ​Proteome profiling in murine models of multiple sclerosis: identification of stage specific markers and culprits for tissue damage.​
    Linker, R. A.; Brechlin, P.; Jesse, S.; Steinacker, P.; Lee, D. H.; Asif, A. R. & Jahn, O.  et al.​ (2009) 
    PLoS One4(10) art. e7624​.​ DOI: https://doi.org/10.1371/journal.pone.0007624 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article | Research Paper
    ​ ​Myelin proteomics: molecular anatomy of an insulating sheath​
    Jahn, O. ; Tenzer, S. & Werner, H. B.​ (2009) 
    Molecular Neurobiology40(1) pp. 55​-72​.​ DOI: https://doi.org/10.1007/s12035-009-8071-2 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article | Research Paper
    ​ ​Differential expression of urocortin in human testicular germ cells in course of spermatogenesis: role for urocortin in male fertility?​
    Tezval, H.; Merseburger, A. S.; Serth, J.; Herrmann, T. W.; Becker, J. U; Jahn, O.   & Kuczyk, M. A.​ (2009) 
    Urology73(4) pp. 901​-905​.​ DOI: https://doi.org/10.1016/j.urology.2008.12.029 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article
    ​ ​Participation of Xenopus Elr-type Proteins in Vegetal mRNA Localization during Oogenesis​
    Arthur, P. K.; Claussen, M. ; Koch, S.; Tarbashevich, K.; Jahn, O.   & Pieler, T. ​ (2009) 
    Journal of Biological Chemistry284(30) pp. 19982​-19992​.​ DOI: https://doi.org/10.1074/jbc.M109.009928 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | 
    ​ ​A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells.​
    Galli, S.; Jahn, O. ; Hitt, R.; Hesse, D.; Opitz, L.; Plessmann, U. & Urlaub, H. et al.​ (2009) 
    PLoS One4(10) art. e7541​.​ DOI: https://doi.org/10.1371/journal.pone.0007541 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article
    ​ ​Multipotent Adult Germline Stem Cells and Embryonic Stem Cells: Comparative Proteomic Approach​
    Dihazi, H.; Dihazi, G. H.; Nolte, J.; Meyer, S.; Jahn, O. ; Mueller, G. A. & Engel, W.​ (2009) 
    Journal of Proteome Research8(12) pp. 5497​-5510​.​ DOI: https://doi.org/10.1021/pr900565b 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​Structural Insights into the Calmodulin-Munc13 Interaction Obtained by Cross-Linking and Mass Spectrometry​
    Dimova, K.; Kalkhof, S.; Pottratz, I.; Ihling, C.; Rodriguez-Castaneda, F.; Liepold, T.   & Griesinger, C.  et al.​ (2009) 
    Biochemistry48(25) pp. 5908​-5921​.​ DOI: https://doi.org/10.1021/bi900300r 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | 
    ​ ​Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical A beta(42) reduces their differentiation potential​
    Uhrig, M.; Brechlin, P.; Jahn, O. ; Knyazev, Y.; Weninger, A.; Busia, L. & Honarnejad, K. et al.​ (2008) 
    BMC Medicine6 art. 38​.​ DOI: https://doi.org/10.1186/1741-7015-6-38 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article
    ​ ​Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease​
    Brechlin, P.; Jahn, O. ; Steinacker, P.; Cepek, L.; Kratzin, H.; Lehnert, S. & Jesse, S. et al.​ (2008) 
    Proteomics8(20) pp. 4357​-4366​.​ DOI: https://doi.org/10.1002/pmic.200800375 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Proteolipid protein is required for transport of sirtuin 2 into CNS myelin​
    Werner, H. B.; Kuhlmann, K.; Shen, S.; Uecker, M.; Schardt, A.; Dimova, K. & Orfaniotou, F. et al.​ (2007) 
    The Journal of Neuroscience27(29) pp. 7717​-7730​.​ DOI: https://doi.org/10.1523/JNEUROSCI.1254-07.2007 
    Details  DOI  PMID  PMC 
  • 2007 Journal Article | Research Paper
    ​ ​Differential activation of CRF receptor subtypes removes stress-induced memory deficit and anxiety​
    Todorovic, C.; Radulovic, J.; Jahn, O. ; Radulovic, M.; Sherrin, T.; Hippel, C. & Spiess, J.​ (2007) 
    European Journal of Neuroscience25(11) pp. 3385​-3397​.​ DOI: https://doi.org/10.1111/j.1460-9568.2007.05592.x 
    Details  DOI  PMID  PMC 
  • 2007 Review
    ​ ​Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms​
    Reumann, S.; Babujee, L.; Ma, C.; Wienkoop, S.; Siemsen, T.; Antonicelli, G. E.& Rasche, N. et al.​ (2007)
    The Plant Cell, 19​(10) pp. 3170​-3193​.​
    Amer Soc Plant Biologists. DOI: https://doi.org/10.1105/tpc.107.050989 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​Technical innovations for the automated identification of gel-separated proteins by MALDI-TOF mass spectrometry​
    Jahn, O. ; Hesse, D.; Reinelt, M. & Kratzin, H. D.​ (2006) 
    Analytical and Bioanalytical Chemistry386(1) pp. 92​-103​.​ DOI: https://doi.org/10.1007/s00216-006-0592-1 
    Details  DOI  PMID  PMC 
  • 2006 Conference Paper | Research Paper
    ​ ​Characterization of the Munc13-calmodulin interaction by photoaffinity labeling​
    Dimova, K.; Kawabe, H.; Betz, A. ; Brose, N.   & Jahn, O. ​ (2006)
    ​Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (11) (Vol. 1763). , Ecole Superieure Biotechnol, Strasbourg, FRANCE.
    Amsterdam​: Elsevier Science Bv. DOI: https://doi.org/10.1016/j.bbamcr.2006.09.017 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Identification and characterization of a stress-inducible and a constitutive small heat-shock protein targeted to the matrix of plant peroxisomes​
    Ma, C.; Haslbeck, M.; Babujee, L.; Jahn, O.   & Reumann, S.​ (2006) 
    Plant Physiology141(1) pp. 47​-60​.​ DOI: https://doi.org/10.1104/pp.105.073841 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Corticotropin-releasing factor binding protein--a ligand trap?​
    Jahn, O. ; Radulovic, J.; Stiedl, O.; Tezval, H.; Eckart, K. & Spiess, J.​ (2005) 
    Mini-Reviews in ... Medicinal Chemistry5(10) pp. 953​-960​.​ DOI: https://doi.org/10.2174/138955705774329500 
    Details  DOI  PMID  PMC 
  • 2005 Journal Article | Research Paper
    ​ ​Corticotropin-releasing factor receptor 1 and central heart rate regulation in mice during expression of conditioned fear​
    Stiedl, O.; Meyer, M.; Jahn, O. ; Ogren, S. O. & Spiess, J.​ (2005) 
    Journal of Pharmacology and Experimental Therapeutics312(3) pp. 905​-916​.​ DOI: https://doi.org/10.1124/jpet.104.075820 
    Details  DOI  PMID  PMC 
  • 2005 Journal Article | Research Paper
    ​ ​The role of CRF receptors in anxiety and depression: implications of the novel CRF1 agonist cortagine​
    Todorovic, C.; Jahn, O. ; Tezval, H.; Hippel, C. & Spiess, J.​ (2005) 
    Neuroscience & Biobehavioral Reviews29(8) pp. 1323​-1333​.​ DOI: https://doi.org/10.1016/j.neubiorev.2005.04.014 
    Details  DOI  PMID  PMC 
  • 2005 Journal Article | Research Paper
    ​ ​Unchanged survival rates of 14-3-3 gamma knockout mice after inoculation with pathological prion protein​
    Steinacker, P. ; Schwarz, P.; Reim, K.; Brechlin, P.; Jahn, O. ; Kratzin, H.   & Aitken, A. et al.​ (2005) 
    Molecular and Cellular Biology25(4) pp. 1339​-1346​.​ DOI: https://doi.org/10.1128/MCB.25.4.1339-1346.2005 
    Details  DOI  PMID  PMC  WoS 
  • 2004 Journal Article | Research Paper
    ​ ​Three-amino acid motifs of urocortin II and III determine their CRF receptor subtype selectivity​
    Jahn, O. ; Tezval, H.; van Werven, L.; Eckart, K. & Spiess, J.​ (2004) 
    Neuropharmacology47(2) pp. 233​-242​.​ DOI: https://doi.org/10.1016/j.neuropharm.2004.03.018 
    Details  DOI  PMID  PMC 
  • 2004 Journal Article | Research Paper
    ​ ​Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model​
    Tezval, H.; Jahn, O. ; Todorovic, C.; Sasse, A.; Eckart, K. & Spiess, J.​ (2004) 
    Proceedings of the National Academy of Sciences of the United States of America101(25) pp. 9468​-9473​.​ DOI: https://doi.org/10.1073/pnas.0403159101 
    Details  DOI  PMID  PMC 
  • 2004 Journal Article | Research Paper
    ​ ​Characterization of peptide-protein interactions using photoaffinity labeling and LC/MS​
    Jahn, O. ; Eckart, K.; Tezval, H. & Spiess, J.​ (2004) 
    Analytical and Bioanalytical Chemistry378(4) pp. 1031​-1036​.​ DOI: https://doi.org/10.1007/s00216-003-2353-8 
    Details  DOI  PMID  PMC 
  • 2004 Journal Article | Research Paper
    ​ ​Calmodulin and Munc13 form a Ca²⁺ sensor/effector complex that controls short-term synaptic plasticity​
    Junge, H. J.; Rhee, J.-S. ; Jahn, O. ; Varoqueaux, F.; Spiess, J. ; Waxham, M. N. & Rosenmund, C. et al.​ (2004) 
    Cell118(3) pp. 389​-401​.​ DOI: https://doi.org/10.1016/j.cell.2004.06.029 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article | Research Paper
    ​ ​Tandem mass spectrometric characterization of branched peptides derived from photoaffinity labeling​
    Jahn, O. ; Tezval, H.; Spiess, J. & Eckart, K.​ (2003) 
    International Journal of Mass Spectrometry228(2-3) pp. 527​-540​.​ DOI: https://doi.org/10.1016/S1387-3806(03)00159-3 
    Details  DOI 
  • 2002 Journal Article | Research Paper
    ​ ​The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure​
    Jahn, O. ; Eckart, K.; Brauns, O.; Tezval, H. & Spiess, J.​ (2002) 
    Proceedings of the National Academy of Sciences of the United States of America99(19) pp. 12055​-12060​.​ DOI: https://doi.org/10.1073/pnas.192449299 
    Details  DOI  PMID  PMC 
  • 2002 Journal Article | Research Paper
    ​ ​Pharmacology and Biology of Corticotropin-Releasing Factor (CRF) Receptors​
    Eckart, K.; Jahn, O. ; Radulovic, J.; Radulovic, M.; Blank, T.; Stiedl, O. & Brauns, O. et al.​ (2002) 
    Receptors and Channels8 pp. 163​-177​.​ DOI: https://doi.org/10.1080/10606820213678 
    Details  DOI 
  • 2002 Journal Article | Research Paper
    ​ ​The use of multiple ion chromatograms in on-line HPLC-MS for the characterization of post-translational and chemical modifications of proteins​
    Jahn, O. ; Hofmann, B.; Brauns, O.; Spiess, J. & Eckart, K.​ (2002) 
    International Journal of Mass Spectrometry214(1) pp. 37​-51​.​ DOI: https://doi.org/10.1016/S1387-3806(01)00593-0 
    Details  DOI 
  • 2001 Journal Article | Research Paper
    ​ ​Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1​
    Hofmann, B. A.; Sydow, S.; Jahn, O. ; van Werven, L.; Liepold, T.; Eckart, K. & Spiess, J.​ (2001) 
    Protein Science10(10) pp. 2050​-2062​.​ DOI: https://doi.org/10.1110/ps.12101 
    Details  DOI  PMID  PMC 
  • 2001 Journal Article | Research Paper
    ​ ​A single amino acid serves as an affinity switch between the receptor and the binding protein of corticotropin-releasing factor: implications for the design of agonists and antagonists​
    Eckart, K.; Jahn, O. ; Radulovic, J.; Tezval, H.; van Werven, L. & Spiess, J.​ (2001) 
    Proceedings of the National Academy of Sciences of the United States of America98(20) pp. 11142​-11147​.​ DOI: https://doi.org/10.1073/pnas.211424998 
    Details  DOI  PMID  PMC 

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