Dr. Martin Johannes Begemann

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  • 2020 Journal Article | 
    ​ ​Erythropoietin as candidate for supportive treatment of severe COVID-19​
    Ehrenreich, H. ; Weissenborn, K.; Begemann, M. ; Busch, M.; Vieta, E. & Miskowiak, K. W.​ (2020) 
    Molecular Medicine26(1).​ DOI: https://doi.org/10.1186/s10020-020-00186-y 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury​
    Pan, H.; Steixner-Kumar, A. A.; Seelbach, A.; Deutsch, N.; Ronnenberg, A.; Tapken, D. & von Ahsen, N.  et al.​ (2020) 
    Molecular Psychiatry26(6) pp. 2471​-2482​.​ DOI: https://doi.org/10.1038/s41380-020-0672-1 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article
    ​ ​Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion​
    Garcia-Agudo, L. F.; Janova, H.; Sendler, L. E.; Arinrad, S.; Steixner, A. A.; Hassouna, I. & Balmuth, E. et al.​ (2019) 
    The FASEB Journal33(7) pp. 8634​-8647​.​ DOI: https://doi.org/10.1096/fj.201900337R 
    Details  DOI 
  • 2019 Journal Article
    Mitjans, M.; Seidel, J.; Begemann, M. ; Bockhop, F.; Seelbach, A.; Bansal, V. & Wesolowski, J. et al.​ (2019) 
    European Neuropsychopharmacology29 pp. S1323​.​ DOI: https://doi.org/10.1016/j.euroneuro.2018.08.471 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model​
    Pan, H.; Oliveira, B. ; Saher, G.; Dere, E. ; Tapken, D.; Mitjans, M. & Seidel, J. et al.​ (2018) 
    Molecular Psychiatry24(10) pp. 1489​-1501​.​ DOI: https://doi.org/10.1038/s41380-017-0011-3 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Microglia ablation alleviates myelin-associated catatonic signs in mice​
    Janova, H. ; Arinrad, S.; Balmuth, E.; Mitjans, M.; Hertel, J.; Habes, M. & Bittner, R. A. et al.​ (2018) 
    Journal of Clinical Investigation128(2) pp. 734​-745​.​ DOI: https://doi.org/10.1172/JCI97032 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia​
    Bansal, V.; Mitjans, M.; Burik, C. A. P.; Linnér, R. K.; Okbay, A.; Rietveld, C. A. & Begemann, M.  et al.​ (2018) 
    Nature Communications9(1).​ DOI: https://doi.org/10.1038/s41467-018-05510-z 
    Details  DOI 
  • 2018 Journal Article | Research Paper | 
    ​ ​Violent aggression predicted by multiple pre-adult environmental hits​
    Mitjans, M.; Seidel, J.; Begemann, M. ; Bockhop, F.; Moya-Higueras, J.; Bansal, V. & Wesolowski, J. et al.​ (2018) 
    Molecular psychiatry, pp. 1​-16​.​ DOI: https://doi.org/10.1038/s41380-018-0043-3 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | 
    ​ ​OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals​
    Ehrenreich, H. ; Mitjans, M.; Van der Auwera, S.; Centeno, T. P. ; Begemann, M. ; Grabe, H.-J. & Bonn, S.  et al.​ (2018) 
    Molecular Psychiatry23 pp. 476​-486​.​ DOI: https://doi.org/10.1038/mp.2016.208 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms​
    Lepeta, K.; Purzycka, K. J.; Pachulska‐Wieczorek, K.; Mitjans, M.; Begemann, M. ; Vafadari, B. & Bijata, K. et al.​ (2017) 
    EMBO Molecular Medicine9(8) pp. 1100​-1116​.​ DOI: https://doi.org/10.15252/emmm.201707723 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Sexual dimorphism of AMBRA1-related autistic features in human and mouse​
    Mitjans, M.; Begemann, M. ; Ju, A.; Dere, E.; Wüstefeld, L.; Hofer, S.   & Hassouna, I.  et al.​ (2017) 
    Translational Psychiatry7(10).​ DOI: https://doi.org/10.1038/tp.2017.213 
    Details  DOI 
  • 2015 Journal Article | 
    ​ ​Amino acid variation in HLA class II proteins is a major determinant of humoral response to common viruses​
    Hammer, C. ; Begemann, M. ; McLaren, P. J.; Bartha, I.; Michel, A.; Klose, B. & Schmitt, C. et al.​ (2015) 
    American journal of human genetics97(5) pp. 738​-743​.​ DOI: https://doi.org/10.1016/j.ajhg.2015.09.008 
    Details  DOI 
  • 2015 Journal Article | Research Paper | 
    ​ ​Autism beyond diagnostic categories: characterization of autistic phenotypes in schizophrenia​
    Kästner, A.; Begemann, M. ; Michel, T. M.; Everts, S.; Stepniak, B. ; Bach, C. & Becker, J. et al.​ (2015) 
    BMC Psychiatry15 art. 115​.​ DOI: https://doi.org/10.1186/s12888-015-0494-x 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper | 
    ​ ​Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes​
    Stepniak, B. ; Kastner, A.; Poggi, G.; Mitjans, M.; Begemann, M. ; Hartmann, A. M. & Van der Auwera, S. et al.​ (2015) 
    EMBO Molecular Medicine7(12) pp. 1565​-1579​.​ DOI: https://doi.org/10.15252/emmm.201505696 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article
    ​ ​A role for prostaglandins in rapid cycling suggested by episode-specific gene expression shifts in peripheral blood mononuclear cells: a preliminary report​
    Gurvich, A.; Begemann, M. ; Dahm, L. ; Sargin, D. ; Miskowiak, K. W. & Ehrenreich, H. ​ (2014) 
    Bipolar Disorders16(8) pp. 881​-888​.​ DOI: https://doi.org/10.1111/bdi.12223 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Accumulated environmental risk determining age at schizophrenia onset: a deep phenotyping-based study​
    Stepniak, B. ; Papiol, S. ; Ramin, A.; Everts, S.; Hennig, L.; Begemann, M.   & Ehrenreich, H. ​ (2014) 
    The Lancet Psychiatry1(6) pp. 444​-453​.​ DOI: https://doi.org/10.1016/S2215-0366(14)70379-7 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Seroprevalence of autoantibodies against brain antigens in health and disease​
    Dahm, L. ; Ott, C. ; Steiner, J.; Stepniak, B. ; Teegen, B.; Saschenbrecker, S. & Hammer, C.  et al.​ (2014) 
    Annals of Neurology76(1) pp. 82​-94​.​ DOI: https://doi.org/10.1002/ana.24189 
    Details  DOI 
  • 2014 Journal Article | 
    ​ ​Apolipoprotein E4 carrier status plus circulating anti-NMDAR1 autoantibodies: association with schizoaffective disorder​
    Hammer, C. ; Zerche, M.; Schneider, A. ; Begemann, M. ; Nave, K.-A.   & Ehrenreich, H. ​ (2014) 
    Molecular Psychiatry19(10) pp. 1054​-1056​.​ DOI: https://doi.org/10.1038/mp.2014.52 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity​
    Hammer, C. ; Stepniak, B. ; Schneider, A. ; Papiol, S. ; Tantra, M. ; Begemann, M.   & Sirén, A.-L.  et al.​ (2014) 
    Molecular Psychiatry19(10) pp. 1143​-1149​.​ DOI: https://doi.org/10.1038/mp.2013.110 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article | 
    ​ ​Mild expression differences of MECP2 influencing aggressive social behavior​
    Tantra, M. ; Hammer, C. ; Kästner, A. ; Dahm, L. ; Begemann, M. ; Bodda, C. & Hammerschmidt, K.  et al.​ (2014) 
    EMBO Molecular Medicine6(5) pp. 662​-684​.​ DOI: https://doi.org/10.1002/emmm.201303744 
    Details  DOI  PMID  PMC 
  • 2013 Journal Article | 
    ​ ​Genetic Markers of a Munc13 Protein Family Member, BAIAP3, Are Gender Specifically Associated with Anxiety and Benzodiazepine Abuse in Mice and Humans​
    Wojcik, S. M. ; Tantra, M. ; Stepniak, B. ; Man, K. Man, Kwun-nok M ; Müller-Ribbe, K.; Begemann, M.   & Ju, A. et al.​ (2013) 
    Molecular Medicine19 pp. 135​-148​.​ DOI: https://doi.org/10.2119/molmed.2013.00033 
    Details  DOI  PMID  PMC 
  • 2013 Journal Article | 
    ​ ​A single gene defect causing claustrophobia​
    El-Kordi, A. ; Kästner, A. ; Grube, S.; Klugmann, M. ; Begemann, M. ; Sperling, S.   & Hammerschmidt, K.  et al.​ (2013) 
    Translational Psychiatry3 art. e254​.​ DOI: https://doi.org/10.1038/tp.2013.28 
    Details  DOI  PMID  PMC 
  • 2013 Journal Article | 
    ​ ​Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters​
    Kästner, A. ; Malzahn, D. ; Begemann, M. ; Hilmes, C.; Bickeböller, H.   & Ehrenreich, H. ​ (2013) 
    BMC Psychiatry13 art. 218​.​ DOI: https://doi.org/10.1186/1471-244X-13-218 
    Details  DOI  PMID  PMC 
  • 2012 Journal Article | 
    ​ ​Common variants of the genes encoding erythropoietin and its receptor modulate cognitive performance in schizophrenia​
    Kästner, A. ; Grube, S.; El-Kordi, A. ; Stepniak, B. ; Friedrichs, H. ; Sargin, D.   & Schwitulla, J. et al.​ (2012) 
    Molecular Medicine18 pp. 1029​-1040​.​ DOI: https://doi.org/10.2119/molmed.2012.00190 
    Details  DOI  PMID  PMC 
  • 2012 Journal Article | 
    ​ ​A myelin gene causative of a catatonia-depression syndrome upon aging​
    Hagemeyer, N.; Goebbels, S. ; Papiol, S. ; Kästner, A. ; Hofer, S. ; Begemann, M.   & Gerwig, U. C. et al.​ (2012) 
    EMBO Molecular Medicine4(6) pp. 528​-539​.​ DOI: https://doi.org/10.1002/emmm.201200230 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article
    ​ ​Prediction of the risk of comorbid alcoholism in schizophrenia by interaction of common genetic variants in the corticotropin-releasing factor system​
    Ribbe, K. ; Ackermann, V.; Schwitulla, J.; Begemann, M. ; Papiol, S. ; Grube, S. & Sperling, S.  et al.​ (2011) 
    Archives of General Psychiatry68(12) pp. 1247​-1256​.​ DOI: https://doi.org/10.1001/archgenpsychiatry.2011.100 
    Details  DOI 
  • 2011 Journal Article | 
    ​ ​Recombinant human erythropoietin delays loss of gray matter in chronic schizophrenia​
    Wüstenberg, T. ; Begemann, M. ; Bartels, C. ; Gefeller, O. ; Stawicki, S. ; Hinze-Selch, D. & Mohr, A.  et al.​ (2011) 
    Molecular Psychiatry16(1) pp. 26​-36​.​ DOI: https://doi.org/10.1038/mp.2010.51 
    Details  DOI 
  • 2011 Journal Article
    ​ ​A phenotype-based genetic association study reveals the contribution of neuregulin1 gene variants to age of onset and positive symptom severity in schizophrenia​
    Papiol, S. ; Begemann, M. ; Rosenberger, A. ; Friedrichs, H. ; Ribbe, K. ; Grube, S. & Schwab, M. H. et al.​ (2011) 
    American Journal of Medical Genetics Part B: Neuropsychiatric Genetics156B(3) pp. 340​-345​.​ DOI: https://doi.org/10.1002/ajmg.b.31168 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article | 
    ​ ​Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia​
    Papiol, S. ; Malzahn, D. ; Kästner, A. ; Sperling, S. ; Begemann, M. ; Stefansson, H. & Bickeböller, H.  et al.​ (2011) 
    Translational Psychiatry1(10) art. e45​.​ DOI: https://doi.org/10.1038/tp.2011.43 
    Details  DOI  PMID  PMC 
  • 2011 Journal Article | Research Paper | 
    ​ ​A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia​
    Grube, S.; Gerchen, M. F.; Adamcio, B. ; Pardo, L. A. ; Martin, S. ; Malzahn, D.   & Papiol, S.  et al.​ (2011) 
    EMBO Molecular Medicine3(6) pp. 309​-319​.​ DOI: https://doi.org/10.1002/emmm.201100135 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms​
    Begemann, M. ; Grube, S.; Papiol, S. ; Malzahn, D. ; Krampe, H. ; Ribbe, K.   & Friedrichs, H.  et al.​ (2010) 
    Archives of General Psychiatry67(9) pp. 879​-888​.​ DOI: https://doi.org/10.1001/archgenpsychiatry.2010.107 
    Details  DOI 
  • 2010 Journal Article | 
    ​ ​The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients​
    Ribbe, K. ; Friedrichs, H. ; Begemann, M. ; Grube, S.; Papiol, S. ; Kästner, A.   & Gerchen, M. F. et al.​ (2010) 
    BMC Psychiatry10 art. 91​.​ DOI: https://doi.org/10.1186/1471-244X-10-91 
    Details  DOI 
  • 2008 Journal Article
    ​ ​Episode-specific differential gene expression of peripheral blood mononuclear cells in rapid cycling supports novel treatment approaches​
    Begemann, M. ; Sargin, D. ; Rossner, M. J. ; Bartels, C. ; Theis, F.; Wichert, S. P. & Stender, N. et al.​ (2008) 
    Molecular Medicine14(9-10) pp. 546​-552​.​ DOI: https://doi.org/10.2119/2008-00053.Begemann 
    Details  DOI 

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