Prof. Dr. Wolfgang Brück

 
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  • 2020 Journal Article
    ​ ​Sepsis-associated encephalopathy and septic encephalitis: an update​
    Tauber, S. C.; Djukic, M. ; Gossner, J.; Eiffert, H. ; Brück, W.   & Nau, R. ​ (2020) 
    Expert Review of Anti-infective Therapy19(2) pp. 215​-231​.​ DOI: https://doi.org/10.1080/14787210.2020.1812384 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Effect of fingolimod on MRI outcomes in patients with paediatric-onset multiple sclerosis: results from the phase 3 PARADIG MS study​
    Arnold, D. L; Banwell, B.; Bar-Or, A.; Ghezzi, A.; Greenberg, B. M; Waubant, E. & Giovannoni, G. et al.​ (2020) 
    Journal of Neurology, Neurosurgery & Psychiatry91(5) pp. 483​-492​.​ DOI: https://doi.org/10.1136/jnnp-2019-322138 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Glatiramer acetate immune modulates B-cell antigen presentation in treatment of MS​
    Häusler, D.; Hajiyeva, Z.; Traub, J. W.; Zamvil, S. S.; Lalive, P. H.; Brück, W.   & Weber, M. S. ​ (2020) 
    Neurology - Neuroimmunology Neuroinflammation7(3) pp. e698​.​ DOI: https://doi.org/10.1212/NXI.0000000000000698 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma​
    Behling, F.; Barrantes-Freer, A. ; Behnes, C. L. ; Stockhammer, F. ; Rohde, V. ; Adel-Horowski, A. & Rodríguez-Villagra, O. A. et al.​ (2020) 
    PLoS One15(3) pp. e0229274​.​ DOI: https://doi.org/10.1371/journal.pone.0229274 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Case Report: A Case of Severe Clinical Deterioration in a Patient With Multiple Sclerosis​
    Breitkopf, K.; Aytulun, A.; Förster, M.; Kraus, B.; Turowski, B.; Huppert, D. & Goebels, N. et al.​ (2020) 
    Frontiers in Neurology11.​ DOI: https://doi.org/10.3389/fneur.2020.00782 
    Details  DOI 
  • 2020 Journal Article
    ​ ​B cells reappear less mature and more activated after their anti-CD20–mediated depletion in multiple sclerosis​
    Nissimov, N.; Hajiyeva, Z.; Torke, S.; Grondey, K.; Brück, W. ; Häusser-Kinzel, S. & Weber, M. S. ​ (2020) 
    Proceedings of the National Academy of Sciences117(41) pp. 25690​-25699​.​ DOI: https://doi.org/10.1073/pnas.2012249117 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort​
    Mynarek, M.; von Hoff, K.; Pietsch, T.; Ottensmeier, H.; Warmuth-Metz, M.; Bison, B. & Pfister, S. et al.​ (2020) 
    Journal of Clinical Oncology38(18) pp. 2028​-2040​.​ DOI: https://doi.org/10.1200/JCO.19.03057 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Iron Heterogeneity in Early Active Multiple Sclerosis Lesions​
    Tham, M.; Frischer, J. M.; Weigand, S. D.; Fitz‐Gibbon, P. D.; Webb, S. M.; Guo, Y. & Adiele, R. C. et al.​ (2020) 
    Annals of Neurology89(3) pp. 498​-510​.​ DOI: https://doi.org/10.1002/ana.25974 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Differential diagnosis of vacuolar myopathies in the NGS era​
    Mair, D.; Biskup, S.; Kress, W.; Abicht, A.; Brück, W. ; Zechel, S. & Knop, K. C. et al.​ (2020) 
    Brain Pathology30(5) pp. 877​-896​.​ DOI: https://doi.org/10.1111/bpa.12864 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Serum neurofilament light chain is a useful biomarker in pediatric multiple sclerosis​
    Reinert, M.-C. ; Benkert, P.; Wuerfel, J.; Michalak, Z.; Ruberte, E.; Barro, C. & Huppke, P.  et al.​ (2020) 
    Neurology - Neuroimmunology Neuroinflammation7(4) pp. e749​.​ DOI: https://doi.org/10.1212/NXI.0000000000000749 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Extensive subpial cortical demyelination is specific to multiple sclerosis​
    Junker, A. ; Wozniak, J.; Voigt, D. ; Scheidt, U. ; Antel, J.; Wegner, C.   & Brück, W.  et al.​ (2020) 
    Brain Pathology30(3) pp. 641​-652​.​ DOI: https://doi.org/10.1111/bpa.12813 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy in paediatric patients with multiple sclerosis: Results from the PARADIGMS study​
    Chitnis, T.; Banwell, B.; Krupp, L.; Arnold, D. L; Bar-Or, A.; Brück, W.   & Giovannoni, G. et al.​ (2020) 
    Multiple Sclerosis Journal27(6) pp. 922​-932​.​ DOI: https://doi.org/10.1177/1352458520936934 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Inhibition of Bruton’s tyrosine kinase interferes with pathogenic B-cell development in inflammatory CNS demyelinating disease​
    Torke, S.; Pretzsch, R.; Häusler, D.; Haselmayer, P.; Grenningloh, R.; Boschert, U. & Brück, W.  et al.​ (2020) 
    Acta Neuropathologica140(4) pp. 535​-548​.​ DOI: https://doi.org/10.1007/s00401-020-02204-z 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Molecular signature of slowly expanding lesions in progressive multiple sclerosis​
    Jäckle, K.; Zeis, T.; Schaeren-Wiemers, N.; Junker, A. ; van der Meer, F. ; Kramann, N.   & Stadelmann, C.  et al.​ (2020) 
    Brain: A Journal of Neurology143(7) pp. 2073​-2088​.​ DOI: https://doi.org/10.1093/brain/awaa158 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany​
    Bittner, S.; Engel, S.; Lange, C.; Weber, M. S. ; Haghikia, A.; Luessi, F. & Korn, T. et al.​ (2019) 
    Der Nervenarzt90(12) pp. 1245-1253​-1253​.​ DOI: https://doi.org/10.1007/s00115-019-0760-0 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Therapy of highly active pediatric multiple sclerosis​
    Huppke, P. ; Huppke, B. ; Ellenberger, D. ; Rostasy, K.; Hummel, H. ; Stark, W.   & Brück, W.  et al.​ (2019) 
    Multiple Sclerosis Journal25(1) art. 135245851773284​.​ DOI: https://doi.org/10.1177/1352458517732843 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia​
    Huppke, P. ; Wegener, E.; Gilley, J.; Angeletti, C.; Kurth, I.; Drenth, J. P. & Stadelmann, C.  et al.​ (2019) 
    Experimental Neurology320 pp. 112958​.​ DOI: https://doi.org/10.1016/j.expneurol.2019.112958 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Severe meningo-/encephalitis after daclizumab therapy for multiple sclerosis​
    Stork, L.; Brück, W. ; von Gottberg, P.; Pulkowski, U.; Kirsten, F.; Glatzel, M. & Rauer, S. et al.​ (2019) 
    Multiple Sclerosis Journal25(12) pp. 1618​-1632​.​ DOI: https://doi.org/10.1177/1352458518819098 
    Details  DOI 
  • 2019 Journal Article
    ​ ​OTUB 1 inhibits CNS autoimmunity by preventing IFN ‐γ‐induced hyperactivation of astrocytes​
    Wang, X.; Mulas, F.; Yi, W.; Brunn, A.; Nishanth, G.; Just, S. & Waisman, A. et al.​ (2019) 
    The EMBO Journal38(10).​ DOI: https://doi.org/10.15252/embj.2018100947 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Reply: Neither human nor mouse is hypercalcaemic with 250 nmol/l 25-hydroxyvitamin D​
    Häusler, D.; Torke, S.; Peelen, E.; Bertsch, T.; Weber, M.; Heilmann, M. & Djukic, M.  et al.​ (2019) 
    Brain: A Journal of Neurology143(2) pp. e10​-e10​.​ DOI: https://doi.org/10.1093/brain/awz389 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Imaging in mice and men: Pathophysiological insights into multiple sclerosis from conventional and advanced MRI techniques​
    Krämer, J.; Brück, W. ; Zipp, F.; Cerina, M.; Groppa, S. & Meuth, S. G.​ (2019) 
    Progress in Neurobiology182 pp. 101663​.​ DOI: https://doi.org/10.1016/j.pneurobio.2019.101663 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Glial fibrillary acidic protein expression alters astrocytic chemokine release and protects mice from cuprizone-induced demyelination​
    Kramann, N. ; Menken, L.; Pförtner, R.; Schmid, S. N.; Stadelmann, C. ; Wegner, C.   & Brück, W. ​ (2019) 
    Glia67(7) pp. 1308​-1319​.​ DOI: https://doi.org/10.1002/glia.23605 
    Details  DOI 
  • 2019 Journal Article
    ​ ​A case of CLIPPERS syndrome responsive to tocilizumab​
    Rempe, T.; Becktepe, J. S.; Metz, I. ; Brück, W. ; Stürner, K. H.; Deuschl, G. & Berg, D. et al.​ (2019) 
    Neurology - Neuroimmunology Neuroinflammation6(3) pp. e545​.​ DOI: https://doi.org/10.1212/NXI.0000000000000545 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome​
    Gross, C. C.; Meyer, C.; Bhatia, U.; Yshii, L.; Kleffner, I.; Bauer, J. & Tröscher, A. R. et al.​ (2019) 
    Nature Communications10(1).​ DOI: https://doi.org/10.1038/s41467-019-13593-5 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​B cell depletion can be effective in multiple sclerosis but failed in a patient with advanced childhood cerebral X-linked adrenoleukodystrophy​
    Rosewich, H. ; Nessler, S. ; Brück, W.   & Gärtner, J. ​ (2019) 
    Therapeutic Advances in Neurological Disorders12.​ DOI: https://doi.org/10.1177/1756286419868133 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Bassoon proteinopathy drives neurodegeneration in multiple sclerosis​
    Schattling, B.; Engler, J. B.; Volkmann, C.; Rothammer, N.; Woo, M. S.; Petersen, M. & Winkler, I. et al.​ (2019) 
    Nature Neuroscience22(6) pp. 887​-896​.​ DOI: https://doi.org/10.1038/s41593-019-0385-4 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​Drug reaction with eosinophilia and systemic symptoms after daclizumab therapy​
    Rauer, S.; Stork, L.; Urbach, H.; Stathi, A.; Marx, A.; Süß, P. & Prinz, M. et al.​ (2018) 
    Neurology91(4) pp. e359​-e363​.​ DOI: https://doi.org/10.1212/WNL.0000000000005854 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Defining distinct features of anti-MOG antibody associated central nervous system demyelination​
    Weber, M. S. ; Derfuss, T.; Metz, I.   & Brück, W. ​ (2018) 
    Therapeutic Advances in Neurological Disorders11 pp. 175628641876208​.​ DOI: https://doi.org/10.1177/1756286418762083 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis​
    Chitnis, T.; Arnold, D. L.; Banwell, B.; Brück, W. ; Ghezzi, A.; Giovannoni, G. & Greenberg, B. et al.​ (2018) 
    New England Journal of Medicine379(11) pp. 1017​-1027​.​ DOI: https://doi.org/10.1056/NEJMoa1800149 
    Details  DOI 
  • 2018 Journal Article
    ​ ​CLIPPERS with longitudinally extensive transverse myelitis: Role of T versus B cells​
    Olmes, D. G.; Metz, I. ; Lee, D.-H.; Rosenwald, A.; Doerfler, A.; Brück, W.   & Linker, R. A. ​ (2018) 
    Journal of the Neurological Sciences385 pp. 96​-98​.​ DOI: https://doi.org/10.1016/j.jns.2017.12.021 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells​
    Page, N.; Klimek, B.; De Roo, M.; Steinbach, K.; Soldati, H.; Lemeille, S. & Wagner, I. et al.​ (2018) 
    Immunity48(5) pp. 937​-950.e8​.​ DOI: https://doi.org/10.1016/j.immuni.2018.04.005 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Spatiotemporal evolution of venous narrowing in acute MS lesions​
    Eisele, P.; Szabo, K.; Ebert, A.; Brueck, W. ; Platten, M. & Gass, A.​ (2018) 
    Neurology - Neuroimmunology Neuroinflammation5(2) pp. e440​.​ DOI: https://doi.org/10.1212/NXI.0000000000000440 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features​
    Deng, M. Y.; Sill, M.; Chiang, J.; Schittenhelm, J.; Ebinger, M.; Schuhmann, M. U. & Monoranu, C.-M. et al.​ (2018) 
    Acta Neuropathologica136(2) pp. 239​-253​.​ DOI: https://doi.org/10.1007/s00401-018-1865-4 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Differential somatostatin, CXCR4 chemokine and endothelin A receptor expression in WHO grade I–IV astrocytic brain tumors​
    Lange, F.; Kaemmerer, D.; Behnke-Mursch, J.; Brück, W. ; Schulz, S. & Lupp, A.​ (2018) 
    Journal of Cancer Research and Clinical Oncology144(7) pp. 1227​-1237​.​ DOI: https://doi.org/10.1007/s00432-018-2645-1 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy​
    Fledrich, R. ; Abdelaal, T.; Rasch, L.; Bansal, V.; Schütza, V.; Brügger, B. & Lüchtenborg, C. et al.​ (2018) 
    Nature Communications9(1).​ DOI: https://doi.org/10.1038/s41467-018-05420-0 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis​
    Stork, L.; Ellenberger, D. ; Beißbarth, T. ; Friede, T. ; Lucchinetti, C. F.; Brück, W.   & Metz, I. ​ (2018) 
    JAMA Neurology75(4) pp. 428​-435​.​ DOI: https://doi.org/10.1001/jamaneurol.2017.4842 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination​
    Barrantes-Freer, A. ; Engel, A. S.; Rodríguez-Villagra, O. A.; Winkler, A. ; Bergmann, M.; Mawrin, C. & Kuempfel, T. et al.​ (2017) 
    Brain Pathology28(2) pp. 225​-233​.​ DOI: https://doi.org/10.1111/bpa.12496 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Pathology of MS subtypes (RIS, CIS, RRMS, PMS, Balo disease)​
    Brück, W. ​ (2017) 
    Journal of the Neurological Sciences381 pp. 5​-6​.​ DOI: https://doi.org/10.1016/j.jns.2017.08.042 
    Details  DOI 
  • 2017 Journal Article
    ​ ​BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions​
    Fard, M. K.; van der Meer, F. ; Sánchez, P.; Cantuti-Castelvetri, L.; Mandad, S. ; Jäkel, S. & Fornasiero, E. F.  et al.​ (2017) 
    Science Translational Medicine9(419) pp. eaam7816​.​ DOI: https://doi.org/10.1126/scitranslmed.aam7816 
    Details  DOI 
  • 2017 Journal Article
    ​ ​ADEM-like presentation, anti-MOG antibodies, and MS pathology: TWO case reports​
    Körtvélyessy, P.; Breu, M.; Pawlitzki, M.; Metz, I. ; Heinze, H.-J.; Matzke, M. & Mawrin, C. et al.​ (2017) 
    Neurology - Neuroimmunology Neuroinflammation4(3) pp. e335​.​ DOI: https://doi.org/10.1212/NXI.0000000000000335 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Interferon beta-1b in treatment-naïve paediatric patients with relapsing–remitting multiple sclerosis: Two-year results from the BETAPAEDIC study​
    Gärtner, J. ; Brück, W. ; Weddige, A. ; Hummel, H. ; Norenberg, C. & Bugge, J.-P.​ (2017) 
    Multiple Sclerosis Journal - Experimental, Translational and Clinical3(4) art. 205521731774762​.​ DOI: https://doi.org/10.1177/2055217317747623 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Association of primary central nervous system vasculitis with the presence of specific human leucocyte antigen gene variant​
    Kraemer, M.; Becker, J.; Horn, P. A.; Schwitalla, J. C.; Keyvani, K.; Metz, I.   & Wegner, C.  et al.​ (2017) 
    Clinical Neurology and Neurosurgery160 pp. 137​-141​.​ DOI: https://doi.org/10.1016/j.clineuro.2017.06.009 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​The value of intraoperative ultrasonography during the resection of relapsed irradiated malignant gliomas in the brain​
    Mursch, K. ; Scholz, M.; Brück, W.   & Behnke-Mursch, J.​ (2017) 
    Ultrasonography36(1) pp. 60​-65​.​ DOI: https://doi.org/10.14366/usg.16015 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial​
    Geletneky, K.; Hajda, J.; Angelova, A. L.; Leuchs, B.; Capper, D.; Bartsch, A. J. & Neumann, J.-O. et al.​ (2017) 
    Molecular Therapy25(12) pp. 2620​-2634​.​ DOI: https://doi.org/10.1016/j.ymthe.2017.08.016 
    Details  DOI 
  • 2017 Journal Article
    ​ ​The Early Adaptive Immune Response in the Pathophysiological Process of Pneumococcal Meningitis​
    Ribes, S.; Nessler, S.; Heide, E.-C.; Malzahn, D. ; Perske, C.; Brück, W.   & Nau, R.​ (2017) 
    The Journal of Infectious Diseases215(1) pp. 150​-158​.​ DOI: https://doi.org/10.1093/infdis/jiw517 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Conference Abstract
    ​ ​Apheresis therapy in multiple sclerosis patients with histopathologically classified immunopathological patterns​
    Stork, L.; Ellenberger, D. ; Beißbarth, T. ; Friede, T. ; Lucchinetti, C.; Brück, W.   & Metz, I. ​ (2016)
    Multiple Sclerosis Journal22 , London, ENGLAND.
    London​: Sage Publications Ltd.
    Details  WoS 
  • 2016 Journal Article
    ​ ​Septic encephalopathy and septic encephalitis‬‬​
    Tauber, S. C.; Eiffert, H. ; Brück, W.   & Nau, R. ​ (2016) 
    Expert Review of Anti-infective Therapy15(2) pp. 121​-132​.​ DOI: https://doi.org/10.1080/14787210.2017.1265448 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Brain iron accumulation in Wilson disease: a post mortem 7 Tesla MRI - histopathological study​
    Dusek, P. ; Bahn, E. ; Litwin, T.; Jabłonka-Salach, K.; Łuciuk, A.; Huelnhagen, T. & Madai, V. I. et al.​ (2016) 
    Neuropathology and Applied Neurobiology43(6) pp. 514​-532​.​ DOI: https://doi.org/10.1111/nan.12341 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis​
    Spadaro, M.; Gerdes, L. A.; Krumbholz, M.; Ertl-Wagner, B.; Thaler, F. S.; Schuh, E. & Metz, I.  et al.​ (2016) 
    Neurology - Neuroimmunology Neuroinflammation3(5) pp. e257​.​ DOI: https://doi.org/10.1212/NXI.0000000000000257 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Laquinimod prevents cuprizone-induced demyelination independent of Toll-like receptor signaling​
    Kramann, N. ; Menken, L.; Hayardeny, L.; Hanisch, U.-K.   & Brück, W. ​ (2016) 
    Neurology - Neuroimmunology Neuroinflammation3(3) pp. e233​.​ DOI: https://doi.org/10.1212/NXI.0000000000000233 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis​
    Metz, I. ; Beißbarth, T. ; Ellenberger, D. ; Pache, F.; Stork, L.; Ringelstein, M. & Aktas, O. et al.​ (2016) 
    Neurology: Neuroimmunology & Neuroinflammation3(2) art. e204​.​ DOI: https://doi.org/10.1212/NXI.0000000000000204 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​Immunopathophysiology of pediatric CNS inflammatory demyelinating diseases​
    Bar-Or, A.; Hintzen, R. Q.; Dale, R. C.; Rostasy, K.; Brück, W.   & Chitnis, T.​ (2016) 
    Neurology87(9 Supplement 2) pp. S12​-S19​.​ DOI: https://doi.org/10.1212/WNL.0000000000002821 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Monitoring of blood parameters under course-modified MS therapy. Substance-specific relevance and current recommendations for action​
    Klotz, L.; Berthele, A.; Brück, W. ; Chan, A.; Flachenecker, P.; Gold, R. & Haghikia, A. et al.​ (2016) 
    Der Nervenarzt87(6) pp. 645​-659​.​ DOI: https://doi.org/10.1007/s00115-016-0077-1 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​CD14 is a key organizer of microglial responses to CNS infection and injury​
    Janova, H. ; Böttcher, C.; Holtman, I. R.; Regen, T. ; Rossum, D. van ; Götz, A.   & Ernst, A.-S.  et al.​ (2016) 
    Glia64(4) pp. 635​-649​.​ DOI: https://doi.org/10.1002/glia.22955 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article
    ​ ​Common molecularcytogenetic alterations in tumors originating from the pineal region​
    Böhrnsen, F. ; Enders, C.; Ludwig, H.-C. ; Brück, W. ; Füzesi, L. & Gutenberg, A.​ (2015) 
    Oncology Letters10(3) pp. 1853-1857​.​ DOI: https://doi.org/10.3892/ol.2015.3383 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper
    ​ ​Extensive Acute Axonal Damage in Pediatric Multiple Sclerosis Lesions​
    Pfeifenbring, S. ; Bunyan, R. F.; Metz, I. ; Roever, C. ; Huppke, P. ; Gärtner, J.   & Lucchinetti, C. F. et al.​ (2015) 
    Annals of Neurology77(4) pp. 655​-667​.​ DOI: https://doi.org/10.1002/ana.24364 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​JC virus antibody status in a pediatric multiple sclerosis cohort: Prevalence, conversion rate and influence on disease severity​
    Huppke, P. ; Hummel, H.-M. ; Ellenberger, D. ; Pfeifenbring, S. ; Stark, W. ; Huppke, B.   & Brueck, W.  et al.​ (2014) 
    Multiple Sclerosis21(4) pp. 382​-387​.​ DOI: https://doi.org/10.1177/1352458514543340 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article
    ​ ​Fungal encephalitis in human autopsy cases is associated with extensive neuronal damage but only minimal repair​
    Tauber, S. C.; Eiffert, H. ; Kellner, S.; Lugert, R. ; Bunkowski, S. ; Schuetze, S. & Perske, C.  et al.​ (2014) 
    Neuropathology and Applied Neurobiology40(5) pp. 610​-627​.​ DOI: https://doi.org/10.1111/nan.12044 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Pediatric onset multiple sclerosis: McDonald criteria 2010 and the contribution of spinal cord MRI​
    Hummel, H.-M. ; Brueck, W. ; Dreha-Kulaczewski, S. F. ; Gärtner, J.   & Wuerfel, J.​ (2013) 
    Multiple Sclerosis19(10) pp. 1330​-1335​.​ DOI: https://doi.org/10.1177/1352458513493033 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | 
    ​ ​Reduced astrocytic NF-kappa B activation by laquinimod protects from cuprizone-induced demyelination​
    Brück, W. ; Pfoertner, R.; Pham, T.; Zhang, J.; Hayardeny, L.; Piryatinsky, V. & Hanisch, U.-K.  et al.​ (2012) 
    Acta Neuropathologica124(3) pp. 411​-424​.​ DOI: https://doi.org/10.1007/s00401-012-1009-1 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | 
    ​ ​Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs​
    Heuer, J. F.; Sauter, P. A.; Pelosi, P.; Herrmann, P. ; Brück, W. ; Perske, C.   & Schoendube, F. et al.​ (2012) 
    CRITICAL CARE16(2) art. R35​.​ DOI: https://doi.org/10.1186/cc11214 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper
    ​ ​MicroRNA regulation in experimental autoimmune encephalomyelitis in mice and marmosets resembles regulation in human multiple sclerosis lesions​
    Lescher, J.; Paap, F.; Schultz, V. ; Redenbach, L.; Scheidt, U. ; Rosewich, H.   & Nessler, S.  et al.​ (2012) 
    Journal of Neuroimmunology246(1-2) pp. 27​-33​.​ DOI: https://doi.org/10.1016/j.jneuroim.2012.02.012 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI​
    Boretius, S. ; Escher, A. ; Dallenga, T. ; Wrzos, C. ; Tammer, R. ; Brück, W.   & Nessler, S.  et al.​ (2011) 
    NeuroImage59(3) pp. 2678​-2688​.​ DOI: https://doi.org/10.1016/j.neuroimage.2011.08.051 
    Details  DOI 
  • 2010 Conference Abstract
    ​ ​Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis​
    Lucas, S.; Antel, J. P.; Wolfgang, B.   & Christine, S.​ (2010)
    Journal of Neuroimmunology228(1-2) , Sitges, SPAIN.
    Amsterdam​: Elsevier Science Bv.
    Details  WoS 
  • 2010 Journal Article | 
    ​ ​p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis​
    Talos, F.; Abraham, A.; Vaseva, A. V.; Holembowski, L. ; Tsirka, S. E.; Scheel, A. & Bode, D. et al.​ (2010) 
    Cell Death and Differentiation17(12) pp. 1816​-1829​.​ DOI: https://doi.org/10.1038/cdd.2010.131 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Mechanisms of acute axonal degeneration in the optic nerve in vivo​
    Knöferle, J. ; Koch, J. C. ; Ostendorf, T.; Michel, U. ; Planchamp, V. ; Vutova, P. & Tönges, L.  et al.​ (2010) 
    Proceedings of the National Academy of Sciences107(13) pp. 6064​-6069​.​ DOI: https://doi.org/10.1073/pnas.0909794107 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Novel CLN8 mutations confirm the clinical and ethnic diversity of late infantile neuronal ceroid lipofuscinosis​
    Reinhardt, K.; Grapp, M.; Schlachter, K.; Brueck, W. ; Gärtner, J.   & Steinfeld, R. ​ (2010) 
    Clinical Genetics77(1) pp. 79​-85​.​ DOI: https://doi.org/10.1111/j.1399-0004.2009.01285.x 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Conference Abstract
    ​ ​Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain​
    Siebert, H. ; Kahle, P. J.; Kramer, M. L.; Isik, T.; Schlüter, O. M. ; Schulz-Schaeffer, W. J.   & Bruck, W. W. ​ (2009)
    Journal of Neurochemistry110 , Leipzig, GERMANY.
    Malden​: Wiley-blackwell Publishing, Inc.
    Details  WoS 
  • 2008 Journal Article
    ​ ​Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology​
    Diem, R. ; Demmer, I. ; Boretius, S. ; Merkler, D. ; Schmelting, B. ; Williams, S. K. & Sättler, M. B.  et al.​ (2008) 
    Investigative Opthalmology & Visual Science49(8) pp. 3707​-3714​.​ DOI: https://doi.org/10.1167/iovs.08-1896 
    Details  DOI  PMID  PMC 
  • 2008 Journal Article | Research Paper | 
    ​ ​Cerebral involvement in axonal Charcot-Marie-Tooth neuropathy caused by mitofusin2 mutations​
    Brockmann, K. ; Dreha-Kulaczewski, S. F. ; Dechent, P. ; Boennemann, C.; Helms, G.; Kyllerman, M. & Brueck, W.  et al.​ (2008) 
    Journal of Neurology255(7) pp. 1049​-1058​.​ DOI: https://doi.org/10.1007/s00415-008-0847-1 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Natalizumab Use in Pediatric Multiple Sclerosis​
    Huppke, P. ; Stark, W. ; Zuercher, C.; Huppke, B. ; Brueck, W.   & Gärtner, J. ​ (2008) 
    Archives of Neurology65(12) pp. 1655​-1658​.​ DOI: https://doi.org/10.1001/archneur.65.12.1655 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article
    ​ ​Broadened and elevated humoral immune response to EBNA1 in pediatric multiple sclerosis​
    Luenemann, J. D.; Huppke, P. ; Robert, S.; Brueck, W. ; Gärtner, J.   & Münz, C.​ (2008) 
    Neurology71(13) pp. 1033​-1035​.​ DOI: https://doi.org/10.1212/01.wnl.0000326576.91097.87 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​Acute onset of fatal vegetative symptoms: Unusual presentation of adult Alexander disease​
    Huttner, H. B.; Richter, G.; Hildebrandt, M.; Bluemcke, I.; Fritscher, T.; Brueck, W.   & Gärtner, J.  et al.​ (2007) 
    European Journal of Neurology14(11) pp. 1251​-1255​.​ DOI: https://doi.org/10.1111/j.1468-1331.2007.01961.x 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage​
    Nessler, S. ; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Hartung, H. - P. & Michaelis, T.  et al.​ (2007) 
    Brain: A Journal of Neurology130(8) pp. 2186​-2198​.​ DOI: https://doi.org/10.1093/brain/awm105 
    Details  DOI  PMID  PMC 
  • 2006 Journal Article | Research Paper
    ​ ​Cathepsin D deficiency is associated with a human neurodegenerative disorder​
    Steinfeld, R. ; Reinhardt, K.; Schreiber, K.; Hillebrand, M.; Kraetzner, R. ; Brück, W.   & Saftig, P.  et al.​ (2006) 
    American journal of human genetics78(6) pp. 988​-998​.​ DOI: https://doi.org/10.1086/504159 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​Plasma exchange therapy for steroid-unresponsive multiple sclerosis relapses. Clinical experience with 16 patients​
    Schilling, S.; Linker, R. A. ; König, F. B. ; Koziolek, M. ; Bähr, M. ; Müller, G. A.   & Paulus, W.  et al.​ (2006) 
    Der Nervenarzt77(4) pp. 430​-438​.​ DOI: https://doi.org/10.1007/s00115-005-2019-1 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Conference Abstract
    ​ ​MRI-histopathology correlation in a clonal mouse EAE model​
    Nessler, S.; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Michaelis, T.   & Bruck, W. W.  et al.​ (2005)
    Multiple Sclerosis Journal11 ​21st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis/10th Annual Meeting of Rehabilitation in MS​, Thessaloniki, GREECE.
    London​: Hodder Arnold, Hodder Headline Plc.
    Details  WoS 
  • 2005 Journal Article
    ​ ​Multicontrast MRI of remyelination in the central nervous system​
    Merkler, D. ; Boretius, S. ; Stadelmann, C. ; Ernsting, T.; Michaelis, T. ; Frahm, J.   & Brück, W. ​ (2005) 
    NMR in Biomedicine18(6) pp. 395​-403​.​ DOI: https://doi.org/10.1002/nbm.972 
    Details  DOI 
  • 2005 Review
    ​ ​Recent advances in pathogenesis and therapy of multiple sclerosis​
    Linker, R. A. ; Stadelmann, C. ; Diem, R. ; Bähr, M. ; Brück, W.  & Gold, R. ​ (2005)
    Fortschritte der Neurologie · Psychiatrie, 73​(12) pp. 715​-727​.​ DOI: https://doi.org/10.1055/s-2004-830256 
    Details  DOI  PMID  PMC  WoS 
  • 2004 Journal Article
    ​ ​Erythropoietin: a candidate compound for neuroprotection in schizophrenia​
    Ehrenreich, H. ; Degner, D. ; Meller, J. ; Brines, M.; Behe, M.; Hasselblatt, M.   & Woldt, H.  et al.​ (2004) 
    Molecular Psychiatry9(1) pp. 42​-54​.​ DOI: https://doi.org/10.1038/sj.mp.4001442 
    Details  DOI 
  • 2001 Journal Article
    ​ ​Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy​
    Kuhlmann, T.; Schroter, A.; Dechent, P. ; Weber, F.; Rusgtenbeck, H. H.; Füzesi, L. & Bruck, W. W.  et al.​ (2001) 
    Journal of Neurology, Neurosurgery & Psychiatry70(2) pp. 259​-262​.​ DOI: https://doi.org/10.1136/jnnp.70.2.259 
    Details  DOI  PMID  PMC  WoS 

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