Prof. Dr. Doron Merkler

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  • 2021 Journal Article | Research Paper
    ​ ​Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation​
    Jafari, M.; Schumacher, A.-M.; Snaidero, N.; Ullrich Gavilanes, E. M.; Neziraj, T.; Kocsis-Jutka, V. & Engels, D. et al.​ (2021) 
    Nature Neuroscience24(3) pp. 355​-367​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article
    ​ ​Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice​
    Steinbach, K.; Vincenti, I.; Egervari, K.; Kreutzfeldt, M.; van der Meer, F. ; Page, N. & Klimek, B. et al.​ (2019) 
    Science Translational Medicine11(498) pp. eaav5519​.​ DOI: 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Bassoon proteinopathy drives neurodegeneration in multiple sclerosis​
    Schattling, B.; Engler, J. B.; Volkmann, C.; Rothammer, N.; Woo, M. S.; Petersen, M. & Winkler, I. et al.​ (2019) 
    Nature Neuroscience22(6) pp. 887​-896​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells​
    Page, N.; Klimek, B.; De Roo, M.; Steinbach, K.; Soldati, H.; Lemeille, S. & Wagner, I. et al.​ (2018) 
    Immunity48(5) pp. 937​-950.e8​.​ DOI: 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping​
    Di Liberto, G.; Pantelyushin, S.; Kreutzfeldt, M.; Page, N.; Musardo, S.; Coras, R. & Steinbach, K. et al.​ (2018) 
    Cell175(2) pp. 458​-471.e19​.​ DOI: 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever​
    Remy, M. M.; Sahin, M.; Flatz, L.; Regen, T. ; Xu, L.; Kreutzfeldt, M. & Fallet, B. et al.​ (2017) 
    Cell Host & Microbe22(3) pp. 354​-365.e5​.​ DOI: 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses​
    Loi, M.; Müller, A.; Steinbach, K.; Niven, J.; da Silva, R. B.; Paul, P. & Ligeon, L.-A. et al.​ (2016) 
    Cell Reports15(5) pp. 1076​-1087​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article
    ​ ​Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology​
    Diem, R. ; Demmer, I. ; Boretius, S. ; Merkler, D. ; Schmelting, B. ; Williams, S. K. & Sättler, M. B.  et al.​ (2008) 
    Investigative Opthalmology & Visual Science49(8) pp. 3707​-3714​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2007 Journal Article | Research Paper
    ​ ​Infratentorial meningioma in an 8-year-old child as first sign of neurofibromatosis type 2​
    Stettner, G. M.; Rostasy, K. M.; Ludwig, H. C. ; Merkler, D. ; Fahsold, R. & Gärtner, J. ​ (2007) 
    Neuropediatrics38(1) pp. 29​-31​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation​
    Maier, K. ; Merkler, D. ; Gerber, J.; Taheri, N.; Kuhnert, A. V.; Williams, S. K. & Neusch, C. et al.​ (2007) 
    Neurobiology of Disease25(3) pp. 514​-525​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage​
    Nessler, S. ; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Hartung, H. - P. & Michaelis, T.  et al.​ (2007) 
    Brain: A Journal of Neurology130(8) pp. 2186​-2198​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2006 Journal Article
    ​ ​Monitoring of EAE onset and progression in the common marmoset monkey by sequential high-resolution 3D MRI​
    Boretius, S. ; Schmelting, B. ; Watanabe, T. ; Merkler, D. ; Tammer, R. ; Czéh, B.   & Michaelis, T.  et al.​ (2006) 
    NMR in Biomedicine19(1) pp. 41​-49​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2006 Journal Article | Research Paper
    ​ ​Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions​
    Sättler, M. B. ; Demmer, I. ; Williams, S. K.; Maier, K. ; Merkler, D. ; Gadjanski, I.   & Stadelmann, C.  et al.​ (2006) 
    Experimental Neurology201(1) pp. 172​-181​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Conference Abstract
    ​ ​MRI-histopathology correlation in a clonal mouse EAE model​
    Nessler, S.; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Michaelis, T.   & Bruck, W. W.  et al.​ (2005)
    Multiple Sclerosis Journal11 ​21st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis/10th Annual Meeting of Rehabilitation in MS​, Thessaloniki, GREECE.
    London​: Hodder Arnold, Hodder Headline Plc.
    Details  WoS 
  • 2005 Journal Article
    ​ ​Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis​
    Diem, R. ; Sättler, M. B. ; Merkler, D. ; Demmer, I. ; Maier, K. ; Stadelmann, C.   & Ehrenreich, H.  et al.​ (2005) 
    Brain128(2) pp. 375​-385​.​ DOI: 
    Details  DOI 
  • 2005 Journal Article
    ​ ​Multicontrast MRI of remyelination in the central nervous system​
    Merkler, D. ; Boretius, S. ; Stadelmann, C. ; Ernsting, T.; Michaelis, T. ; Frahm, J.   & Brück, W. ​ (2005) 
    NMR in Biomedicine18(6) pp. 395​-403​.​ DOI: 
    Details  DOI 
  • 2005 Journal Article | Research Paper
    ​ ​HIV-tat-mediated BCl-X-L delivery protects retinal ganglion cells during experimental autoimmune optic neuritis​
    Diem, R. ; Taheri, N.; Dietz, G. P. H. ; Kuhnert, A. V.; Maier, K. ; Sattler, M. & Gadjanski, L.  et al.​ (2005) 
    Neurobiology of Disease20(2) pp. 218​-226​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Simvastatin treatment does not protect retinal ganglion cells from degeneration in a rat model of autoimmune optic neuritis​
    Sattler, M.; Diem, R. ; Merkler, D. ; Demmer, I. ; Boger, I.; Stadelmann, C.   & Bähr, M. ​ (2005) 
    Experimental Neurology193(1) pp. 163​-171​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article
    ​ ​Sequential loss of myelin proteins during Wallerian degeneration in the human spinal cord​
    Buss, A.; Pech, K.; Merkler, D. ; Kakulas, B. A.; Martin, D.; Schoenen, J. & Noth, J. et al.​ (2005) 
    Brain128 pp. 356​-364​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2004 Journal Article | 
    ​ ​Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis​
    Sättler, M. B. ; Merkler, D. ; Maier, K. ; Stadelmann, C. ; Ehrenreich, H. ; Bähr, M.   & Diem, R. ​ (2004) 
    Cell Death and Differentiation11(Suppl. 2) pp. S181​-S192​.​ DOI: 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis​
    Schneider, A. ; Araújo, G. W.; Trajkovic, K.; Herrmann, M. M.; Merkler, D. ; Mandelkow, E.-M. & Weissert, R. et al.​ (2004) 
    Journal of Biological Chemistry279(53) pp. 55833​-55839​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 

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