Prof. Dr. Markus Otto

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  • 2022 Journal Article | Research Paper | 
    ​ ​LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease​
    Koper, M. J.; Tomé, S. O.; Gawor, K.; Belet, A.; Van Schoor, E.; Schaeverbeke, J. & Vandenberghe, R. et al.​ (2022) 
    Acta Neuropathologica Communications10(1) art. 128​.​ DOI: https://doi.org/10.1186/s40478-022-01432-6 
    Details  DOI 
  • 2022 Journal Article
    ​ ​CSF levels of SNAP-25 are increased early in Creutzfeldt-Jakob and Alzheimer’s disease​
    Halbgebauer, S.; Steinacker, P. ; Hengge, S.; Oeckl, P.; Abu Rumeileh, S.; Anderl-Straub, S. & Lombardi, J. et al.​ (2022) 
    Journal of Neurology, Neurosurgery & Psychiatry, art. jnnp-2021-328646​.​ DOI: https://doi.org/10.1136/jnnp-2021-328646 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Relationship of serum beta‐synuclein with blood biomarkers and brain atrophy​
    Oeckl, P.; Anderl‐Straub, S.; Danek, A.; Diehl‐Schmid, J.; Fassbender, K.; Fliessbach, K. & Halbgebauer, S. et al.​ (2022) 
    Alzheimer's & Dementia, art. alz.12790​.​ DOI: https://doi.org/10.1002/alz.12790 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes​
    Schaeverbeke, J.; Tomé, S. O.; Ronisz, A.; Ospitalieri, S.; Arnim, C. A. F. von ; Otto, M.   & Vandenberghe, R. et al.​ (2022) 
    Alzheimer's & Dementia, art. alz.12794​.​ DOI: https://doi.org/10.1002/alz.12794 
    Details  DOI 
  • 2021 Journal Article
    ​ ​Different Inflammatory Signatures in Alzheimer’s Disease and Frontotemporal Dementia Cerebrospinal Fluid​
    Boström, G.; Freyhult, E.; Virhammar, J.; Alcolea, D.; Tumani, H. ; Otto, M.   & Brundin, R.-M. et al.​ (2021) 
    Journal of Alzheimer's Disease81(2) pp. 629​-640​.​ DOI: https://doi.org/10.3233/JAD-201565 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Network Localization of Alien Limb in Patients with Corticobasal Syndrome​
    Tetreault, A. M.; Phan, T.; Petersen, K. J.; Claassen, D. O.; Neth, B. J.; Graff‐Radford, J. & Albrecht, F. et al.​ (2020) 
    Annals of Neurology88(6) pp. 1118​-1131​.​ DOI: https://doi.org/10.1002/ana.25901 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Serum neurofilament light chain (NFL) remains unchanged during electroconvulsive therapy​
    Besse, M. ; Belz, M. ; Folsche, T.; Vogelgsang, J.; Methfessel, I. ; Steinacker, P.   & Otto, M.  et al.​ (2020) 
    The World Journal of Biological Psychiatry21(2) pp. 148​-154​.​ DOI: https://doi.org/10.1080/15622975.2019.1702717 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Disentangling brain functional network remodeling in corticobasal syndrome – A multimodal MRI study​
    Ballarini, T.; Albrecht, F.; Mueller, K.; Jech, R.; Diehl-Schmid, J.; Fliessbach, K. & Kassubek, J. et al.​ (2020) 
    NeuroImage: Clinical25 pp. 102112​.​ DOI: https://doi.org/10.1016/j.nicl.2019.102112 
    Details  DOI 
  • 2020 Journal Article | Erratum | 
    ​ ​Correction to: Different aspects of Alzheimer’s disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia​
    Thal, D. R.; Ronisz, A.; Tousseyn, T.; Upadhaya, A. R.; Balakrishnan, K.; Vandenberghe, R. & Vandenbulcke, M. et al.​ (2020) 
    Acta Neuropathologica Communications8(1).​ DOI: https://doi.org/10.1186/s40478-020-01005-5 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Gedächtnisambulanzen in Deutschland – strukturell-organisatorische Voraussetzungen und Aufgabenfelder​
    Hausner, L.; Frölich, L.; von Arnim, C. A. F. ; Bohlken, J.; Dodel, R.; Otto, M.   & Rapp, M. et al.​ (2020) 
    Der Nervenarzt,.​ DOI: https://doi.org/10.1007/s00115-020-01007-7 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes​
    Tomé, S. O.; Vandenberghe, R.; Ospitalieri, S.; Van Schoor, E.; Tousseyn, T.; Otto, M.   & von Arnim, C. A. F.  et al.​ (2020) 
    Acta Neuropathologica Communications8(1).​ DOI: https://doi.org/10.1186/s40478-020-00934-5 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen​
    Wurster, C. D.; Steinacker, P. ; Günther, R. ; Koch, J. C. ; Lingor, P. ; Uzelac, Z. & Witzel, S. et al.​ (2019) 
    Journal of Neurology267(1) pp. 36​-44​.​ DOI: https://doi.org/10.1007/s00415-019-09547-y 
    Details  DOI 
  • 2019 Journal Article
    ​ ​CSF and blood Kallikrein-8: a promising early biomarker for Alzheimer’s disease​
    Teuber-Hanselmann, S.; Rekowski, J.; Vogelgsang, J.; von Arnim, C. ; Reetz, K.; Stang, A. & Jöckel, K.-H. et al.​ (2019) 
    Journal of Neurology, Neurosurgery & Psychiatry91(1) pp. 40​-48​.​ DOI: https://doi.org/10.1136/jnnp-2019-321073 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Different aspects of Alzheimer’s disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia​
    Thal, D. R.; Ronisz, A.; Tousseyn, T.; Rijal Upadhaya, A.; Balakrishnan, K.; Vandenberghe, R. & Vandenbulcke, M. et al.​ (2019) 
    Acta Neuropathologica Communications7(1).​ DOI: https://doi.org/10.1186/s40478-019-0837-9 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Neurochemical markers in CSF of adolescent and adult SMA patients undergoing nusinersen treatment​
    Wurster, C. D.; Günther, R. ; Steinacker, P. ; Dreyhaupt, J.; Wollinsky, K.; Uzelac, Z. & Witzel, S. et al.​ (2019) 
    Therapeutic Advances in Neurological Disorders12 pp. 175628641984605​.​ DOI: https://doi.org/10.1177/1756286419846058 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging​
    Albrecht, F.; Mueller, K.; Ballarini, T.; Lampe, L.; Diehl-Schmid, J.; Fassbender, K. & Fliessbach, K. et al.​ (2019) 
    Cortex117 pp. 33​-40​.​ DOI: https://doi.org/10.1016/j.cortex.2019.02.015 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Routine Cerebrospinal Fluid (CSF) Parameters in Patients With Spinal Muscular Atrophy (SMA) Treated With Nusinersen​
    Wurster, C. D.; Koch, J. C. ; Cordts, I.; Dreyhaupt, J.; Otto, M. ; Uzelac, Z. & Witzel, S. et al.​ (2019) 
    Frontiers in Neurology10.​ DOI: https://doi.org/10.3389/fneur.2019.01179 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​
    Lewczuk, P. ; Riederer, P.; O’Bryant, S. E.; Verbeek, M. M.; Dubois, B.; Visser, P. J. & Jellinger, K. A. et al.​ (2018) 
    The World Journal of Biological Psychiatry19(4) pp. 244​-328​.​ DOI: https://doi.org/10.1080/15622975.2017.1375556 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Serum neurofilament light chain in behavioral variant frontotemporal dementia​
    Steinacker, P. ; Anderl-Straub, S.; Diehl-Schmid, J.; Semler, E.; Uttner, I.; von Arnim, C. A. & Barthel, H. et al.​ (2018) 
    Neurology91(15) pp. e1390​-e1401​.​ DOI: https://doi.org/10.1212/WNL.0000000000006318 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Micro-droplet arrays for micro-compartmentalization using an air/water interface​
    Kunding, A. H.; Busk, L. L.; Webb, H.; Klafki, H. W. ; Otto, M. ; Kutter, J. P. & Dufva, M.​ (2018) 
    Lab on a Chip18(18) pp. 2797​-2805​.​ DOI: https://doi.org/10.1039/C8LC00608C 
    Details  DOI 
  • 2018 Journal Article
    ​ ​A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests​
    Schroeter, M. L.; Pawelke, S.; Bisenius, S.; Kynast, J.; Schuemberg, K.; Polyakova, M. & Anderl-Straub, S. et al.​ (2018) 
    Frontiers in Aging Neuroscience10.​ DOI: https://doi.org/10.3389/fnagi.2018.00011 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls​
    Denk, J.; Oberhauser, F.; Kornhuber, J. ; Wiltfang, J. ; Fassbender, K.; Schroeter, M. L. & Volk, A. E. et al.​ (2018) 
    PLoS One13(5) pp. e0197329​.​ DOI: https://doi.org/10.1371/journal.pone.0197329 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​A language-based sum score for the course and therapeutic intervention in primary progressive aphasia​
    Semler, E.; Anderl-Straub, S.; Uttner, I.; Diehl-Schmid, J.; Danek, A.; Einsiedler, B. & Fassbender, K. et al.​ (2018) 
    Alzheimer's Research & Therapy10(1).​ DOI: https://doi.org/10.1186/s13195-018-0345-3 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation​
    Teunissen, C. E.; Otto, M. ; Engelborghs, S.; Herukka, S.-K.; Lehmann, S.; Lewczuk, P.   & Lleó, A. et al.​ (2018) 
    Alzheimer's Research & Therapy10(1).​ DOI: https://doi.org/10.1186/s13195-018-0359-x 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias​
    Steinacker, P. ; Semler, E.; Anderl-Straub, S.; Diehl-Schmid, J.; Schroeter, M. L.; Uttner, I. & Foerstl, H. et al.​ (2017) 
    Neurology88(10) pp. 961​-969​.​ DOI: https://doi.org/10.1212/WNL.0000000000003688 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Biomarker bei Demenzen und anderen neurodegenerativen Erkrankungen​
    Wiltfang, J. ; Lewczuk, P.   & Otto, M. ​ (2016) 
    Der Nervenarzt87(12) pp. 1305​-1309​.​ DOI: https://doi.org/10.1007/s00115-016-0238-2 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Frontotemporale Lobärdegeneration – Prägnanztypen, Diagnosekriterien und Therapieansätze​
    Wiltfang, J. ; Feneberg, E.; Anderl-Straub, S. & Otto, M. ​ (2016) 
    PSYCH up2date10(03) pp. 179​-190​.​ DOI: https://doi.org/10.1055/s-0042-102275 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Modified serpinA1 as risk marker for Parkinson’s disease dementia: Analysis of baseline data​
    Halbgebauer, S.; Nagl, M.; Klafki, H. ; Haußmann, U.; Steinacker, P. ; Oeckl, P. & Kassubek, J. et al.​ (2016) 
    Scientific Reports6(1).​ DOI: https://doi.org/10.1038/srep26145 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia​
    Teipel, S. J.; Raiser, T.; Riedl, L.; Riederer, I.; Schroeter, M. L.; Bisenius, S. & Schneider, A.  et al.​ (2016) 
    Cortex83 pp. 124​-135​.​ DOI: https://doi.org/10.1016/j.cortex.2016.07.004 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay​
    Kraus, I. ; Besong Agbo, D.; Otto, M. ; Wiltfang, J.   & Klafki, H. ​ (2015) 
    Scientific Reports5(1) art. 12767​.​ DOI: https://doi.org/10.1038/srep12767 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Capillary isoelectric focusing immunoassay as a new nanoscale approach for the detection of oligoclonal bands​
    Halbgebauer, S.; Haußmann, U.; Klafki, H. ; Tumani, H. ; Wiltfang, J.   & Otto, M. ​ (2014) 
    ELECTROPHORESIS36(2) pp. 355​-362​.​ DOI: https://doi.org/10.1002/elps.201400339 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease​
    Otto, M. ; Wiltfang, J. ; Cepek, L. ; Neumann, M.; Mollenhauer, B. ; Steinacker, P.   & Ciesielczyk, B.  et al.​ (2012) 
    Neurology58(2) pp. 192​-197​.​ DOI: https://doi.org/10.1212/wnl.58.2.192 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Decreased  β-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease​
    Otto, M. ; Esselmann, H. ; Schulz-Schaeffer, W. ; Neumann, M.; Schröter, A. ; Ratzka, P.   & Cepek, L.  et al.​ (2012) 
    Neurology54(5) pp. 1099​-1102​.​ DOI: https://doi.org/10.1212/wnl.54.5.1099 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Decreased CSF amyloid  42 and normal tau levels in dementia with Lewy bodies​
    Tschampa, H. J.; Schulz-Schaeffer, W. ; Wiltfang, J. ; Poser, S. ; Otto, M. ; Neumann, M. & Kretzschmar, H. A.  et al.​ (2012) 
    Neurology56(4).​ DOI: https://doi.org/10.1212/wnl.56.4.576 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study​
    Otto, M. ; Wiltfang, J. ; Schütz, E. ; Zerr, I. ; Otto, A.; Pfahlberg, A.   & Gefeller, O.  et al.​ (2011) 
    BMJ316(7131) pp. 577​-582​.​ DOI: https://doi.org/10.1136/bmj.316.7131.577 
    Details  DOI 
  • 2011 Book Chapter
    ​ ​Neurotransmitterveränderungen bei der Alzheimer Demenz​
    Kornhuber, J. ; Gundacker, I.; Maler, M. ; Otto, M.  & Wiltfang, J. ​ (2011)
    In:​Förstl, Hans; Bickel, Horst; Kurz, Alexander​ (Eds.), Alzheimer Demenz - Grundlagen, Klinik und Therapie. ​Berlin, Heidelberg: ​Springer. DOI: https://doi.org/10.1007/978-3-642-60228-3_5 
    Details  DOI 
  • 2009 Journal Article
    ​ ​Elevated levels of serum SlOO beta protein in scrapie hamsters​
    Otto, M. ; Beekes, M.; Wiltfang, J. ; Bahn, E. ; Poser, S.   & Diringer, H.​ (2009) 
    Journal of Neurovirology4(5) pp. 572​-573​.​ DOI: https://doi.org/10.3109/13550289809113503 
    Details  DOI 
  • 2008 Journal Article | Research Paper
    ​ ​Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis​
    Hein (née Maier), K.; Köhler, A.; Diem, R. ; Sättler, M. B. ; Demmer, I. ; Lange, P.   & Bähr, M.  et al.​ (2008) 
    Neuroscience Letters436(1) pp. 72​-76​.​ DOI: https://doi.org/10.1016/j.neulet.2008.02.064 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Flupirtine as Neuroprotective Add-On Therapy in Autoimmune Optic Neuritis​
    Sättler, M. B. ; Williams, S. K.; Neusch, C.; Otto, M. ; Pehlke, J. R.; Bähr, M.   & Diem, R. ​ (2008) 
    The American Journal of Pathology173(5) pp. 1496​-1507​.​ DOI: https://doi.org/10.2353/ajpath.2008.080491 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Unaltered apoptotic behaviour of mononuclear cells from patients with sporadic Creutzfeldt-Jakob disease​
    Ratzka, P. ; Schröter, A. ; Cepek, L. ; Henkel, K. ; Wiltfang, J. ; Kretzschmar, H. A.   & Prange, H.  et al.​ (2006) 
    Journal of Neurology248(8) pp. 690​-694​.​ DOI: https://doi.org/10.1007/pl00007834 
    Details  DOI 
  • 2006 Journal Article
    ​ ​Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease​
    Buerger, K.; Otto, M. ; Teipel, S. J.; Zinkowski, R.; Blennow, K.; DeBernardis, J. & Kerkman, D. et al.​ (2006) 
    Neurobiology of Aging27(1) pp. 10​-15​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2004.12.003 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Tau, phospho-tau, and S-100B in the cerebrospinal fluid of children with multiple sclerosis​
    Rostasy, K.; Withut, E.; Pohl, D.; Lange, P. ; Ciesielcyk, B. ; Diem, R.   & Gärtner, J.  et al.​ (2005) 
    Journal of Child Neurology20(10) pp. 822​-825​.​ DOI: https://doi.org/10.1177/08830738050200100801 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Unchanged survival rates of 14-3-3 gamma knockout mice after inoculation with pathological prion protein​
    Steinacker, P. ; Schwarz, P.; Reim, K.; Brechlin, P.; Jahn, O. ; Kratzin, H.   & Aitken, A. et al.​ (2005) 
    Molecular and Cellular Biology25(4) pp. 1339​-1346​.​ DOI: https://doi.org/10.1128/MCB.25.4.1339-1346.2005 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article
    ​ ​Tau protein, A beta 42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies​
    Mollenhauer, B. ; Cepek, L.; Bibl, M. ; Wiltfang, J.; Schulz-Schaeffer, W. J. ; Ciesielczyk, B.   & Neumann, M. et al.​ (2005) 
    Dementia and Geriatric Cognitive Disorders19(2-3) pp. 164​-170​.​ DOI: https://doi.org/10.1159/000083178 
    Details  DOI  PMID  PMC  WoS 
  • 2004 Journal Article
    ​ ​Lithium Decreases Secretion of Aβ1–42 and C-Truncated Species Aβ1–37/38/39/40 in Chicken Telencephalic Cultures but Specifically Increases Intracellular Aβ1–38​
    Esselmann, H. ; Maler, J. M. ; Kunz, N. ; Otto, M. ; Paul, S. ; Lewczuk, P.   & Rüther, E.  et al.​ (2004) 
    Neurodegenerative Diseases1(4-5) pp. 236​-241​.​ DOI: https://doi.org/10.1159/000080992 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Electrophoretic separation of amyloid β peptides in plasma​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Paul, S.; Svitek, J.; Miertschischk, J. & Meyrer, R. et al.​ (2004) 
    ELECTROPHORESIS25(20) pp. 3336​-3343​.​ DOI: https://doi.org/10.1002/elps.200406068 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Cerebrospinal fluid amyloidβ peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloidβ peptides​
    Bibl, M. ; Esselmann, H. ; Otto, M. ; Lewczuk, P. ; Cepek, L. ; Rüther, E.   & Kornhuber, J.  et al.​ (2004) 
    ELECTROPHORESIS25(17) pp. 2912​-2918​.​ DOI: https://doi.org/10.1002/elps.200305992 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Tau Protein Phosphorylated at Threonine 181 in CSF as a Neurochemical Biomarker in Alzheimer's Disease: ​Original Data and Review of the Literature​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Beck, G.; Maler, J. M. ; Otto, M.   & Kornhuber, J.  et al.​ (2004) 
    Journal of Molecular Neuroscience23(1-2) pp. 115​-122​.​ DOI: https://doi.org/10.1385/jmn:23:1-2:115 
    Details  DOI  PMID  PMC 
  • 2004 Journal Article
    ​ ​Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease​
    Lewczuk, P. ; Esselmann, H. ; Groemer, T. W.; Bibl, M. ; Maler, J. M. ; Steinacker, P.   & Otto, M.  et al.​ (2004) 
    Biological Psychiatry55(5) pp. 524​-530​.​ DOI: https://doi.org/10.1016/j.biopsych.2003.10.014 
    Details  DOI  PMID  PMC 
  • 2003 Journal Article
    ​ ​Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation​
    Wiltfang, J. ; Esselmann, H. ; Bibl, M. ; Smirnov, A. ; Otto, M. ; Paul, S.   & Schmidt, B.  et al.​ (2003) 
    Journal of Neurochemistry81(3) pp. 481​-496​.​ DOI: https://doi.org/10.1046/j.1471-4159.2002.00818.x 
    Details  DOI 
  • 2002 Journal Article
    ​ ​Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy​
    Steinhoff, B. J. ; Tumani, H. ; Otto, M. ; Mursch, K. ; Wiltfang, J. ; Herrendorf, G.   & Bittermann, H.-J.  et al.​ (2002) 
    Epilepsy Research36(1) pp. 75​-82​.​ DOI: https://doi.org/10.1016/s0920-1211(99)00026-1 
    Details  DOI 
  • 2002 Journal Article
    ​ ​Boxing and Running Lead to a Rise in Serum Levels of S-100B Protein​
    Otto, M. ; Holthusen, S. ; Bahn, E. ; Söhnchen, N. ; Wiltfang, J. ; Geese, R. & Fischer, A.  et al.​ (2002) 
    International Journal of Sports Medicine21(8) pp. 551​-555​.​ DOI: https://doi.org/10.1055/s-2000-8480 
    Details  DOI 
  • 2002 Journal Article
    ​ ​Specific 14-3-3 isoform detection and immunolocalization in prion diseases​
    Baxter, H. C.; Fraser, J. R.; Liu, W.-G.; Forster, J. L.; Clokie, S.; Steinacker, P.   & Otto, M.  et al.​ (2002) 
    Biochemical Society Transactions30(4) pp. 387​-391​.​ DOI: https://doi.org/10.1042/bst0300387 
    Details  DOI  PMID  PMC 
  • 2001 Journal Article
    ​ ​Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease​
    Itoh, N.; Arai, H.; Urakami, K.; Ishiguro, K.; Ohno, H.; Hampel, H. & Buerger, K. et al.​ (2001) 
    Annals of Neurology50(2) pp. 150​-156​.​ DOI: https://doi.org/10.1002/ana.1054 
    Details  DOI 
  • 2000 Journal Article
    ​ ​Creutzfeldt-Jakob disease and oxidative stress​
    Bleich, S. ; Kropp, S. ; Degner, D. ; Zerr, I. ; Pilz, J. ; Gleiter, C. H.   & Otto, M.  et al.​ (2000) 
    Acta Neurologica Scandinavica101(5) pp. 332​-334​.​ DOI: https://doi.org/10.1034/j.1600-0404.2000.9s290a.x 
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Kinetics of Serum Neuron-Specific Enolase and Prolactin in Patients After Single Epileptic Seizures​
    Tumani, H. ; Otto, M. ; Gefeller, O. ; Wiltfang, J. ; Herrendorf, G. ; Mogge, S.   & Steinhoff, B. J. ​ (1999) 
    Epilepsia40(6) pp. 713​-718​.​ DOI: https://doi.org/10.1111/j.1528-1157.1999.tb00768.x 
    Details  DOI 
  • 1999 Journal Article
    ​ ​Laborchemische Verfahren in der Differentialdiagnose der Creutzfeldt-Jakob-Krankheit​
    Otto, M. ; Zerr, I. ; Wiltfang, J. ; Weber, T.; Kretzschmar, H. ; Poser, S.   & Felgenhauer, K. ​ (1999) 
    Deutsches Ärzteblatt33.​
    Details 
  • 1999 Journal Article
    ​ ​Tau Protein: Ein potentieller biologischer Indikator zur Früherkennung der Alzheimer-Krankheit: ​Anmerkung zur Arbeit von K. Buch et al. Nervenarzt (1998) 69: 379–385​
    Otto, M. ; Wiltfang, J. ; Poser, S.   & Kornhuber, J. ​ (1999) 
    Der Nervenarzt70(7) pp. 668​-670​.​ DOI: https://doi.org/10.1007/s001150050494 
    Details  DOI 
  • 1999 Journal Article
    ​ ​Late Increase of Serum S100 β Protein Levels in Hamsters after Oral or Intraperitoneal Infection with Scrapie​
    Beekes, M.; Otto, M. ; Wiltfang, J. ; Bahn, E. ; Poser, S.   & Baier, M.​ (1999) 
    The Journal of Infectious Diseases180(2) pp. 518​-520​.​ DOI: https://doi.org/10.1086/314907 
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Isoform Pattern of 14-3-3 Proteins in the Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease​
    Wiltfang, J. ; Otto, M. ; Baxter, H. C.; Bodemer, M. ; Steinacker, P. ; Bahn, E.   & Zerr, I.  et al.​ (1999) 
    Journal of Neurochemistry73(6) pp. 2485​-2490​.​ DOI: https://doi.org/10.1046/j.1471-4159.1999.0732485.x 
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Elevated Serum Levels of Astroglial S100β in Patients with Liver Cirrhosis Indicate Early and Subclinical Portal-Systemic Encephalopathy​
    Wiltfang, J. ; Nolte, W. ; Otto, M. ; Wildberg, J. ; Bahn, E. ; Figulla, H. R.   & Pralle, L. et al.​ (1999) 
    Metabolic Brain Disease14(4) pp. 239​-251​.​ DOI: https://doi.org/10.1023/a:1020785009005 
    Details  DOI  PMID  PMC 
  • 1998 Journal Article
    ​ ​Laborchemische Methoden in der Differentialdiagnose der Creutzfeldt-Jakob-Erkrankung​
    Otto, M. ; Wiltfang, J.   & Poser, S. ​ (1998) 
    Psycho12.​
    Details 
  • 1998 Journal Article
    ​ ​Authors reply; Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study​
    Otto, M. ; Wiltfang, J. ; Schütz, E. ; Zerr, I. ; Otto, A.; Pfahlberg, A.   & Gefeller, O.  et al.​ (1998) 
    British Medical Journal317 art. 472​.​
    Details 
  • 1998 Journal Article
    ​ ​Labordiagnostik der Alzheimer-Demenz​
    Wiltfang, J. ; Otto, M.   & Kornhuber, J. ​ (1998) 
    Psycho12.​
    Details 
  • 1998 Journal Article
    ​ ​Changing levels of S100 protein in serum after epileptic seizures​
    Otto, M. ; Wiltfang, J. ; Mogge, S. ; Tumani, H. ; Pfahlberg, A.   & Steinhoff, B. ​ (1998) 
    Epilepsia39 art. 73​.​
    Details 
  • 1998 Journal Article
    ​ ​Therapeutische Ansätze bei der Creutzfeldt-Jakob-Krankheit​
    Otto, M. ; Ratzka, P. ; Wiltfang, J. ; Boekhoff, I. ; Poser, S.   & Prange, H. W. ​ (1998) 
    Deutsches Ärzteblatt95(51-52) pp. 3283​-3286​.​
    Details 
  • 1998 Journal Article
    ​ ​Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease​
    Zerr, I. ; Bodemer, M. ; Gefeller, O. ; Otto, M. ; Poser, S. ; Wiltfang, J.   & Windl, O.  et al.​ (1998) 
    Annals of Neurology43(1) pp. 32​-40​.​ DOI: https://doi.org/10.1002/ana.410430109 
    Details  DOI 
  • 1998 Journal Article
    ​ ​Decrease of S100 beta protein in serum of patients with amyotrophic lateral sclerosis​
    Otto, M. ; Bahn, E. ; Wiltfang, J. ; Boekhoff, I.   & Beuche, W. ​ (1998) 
    Neuroscience Letters240(3) pp. 171​-173​.​ DOI: https://doi.org/10.1016/s0304-3940(97)00947-6 
    Details  DOI  PMID  PMC 

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