Prof. Dr. rer. nat. Ralph H. Kehlenbach

 
Staff Status
unigoe
 

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  • 2021 Journal Article
    ​ ​The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors​
    Baade, I. ; Hutten, S.; Sternburg, E. L.; Pörschke, M.; Hofweber, M.; Dormann, D. & Kehlenbach, R. H. ​ (2021) 
    Journal of Biological Chemistry296 art. S0021925821004476​.​ DOI: https://doi.org/10.1016/j.jbc.2021.100659 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​Sequestosome 1 Is Part of the Interaction Network of VAPB​
    James, C.; Lenz, C.; Urlaub, H.   & Kehlenbach, R. H. ​ (2021) 
    International Journal of Molecular Sciences22(24) pp. 13271​.​ DOI: https://doi.org/10.3390/ijms222413271 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Overview | 
    ​ ​The Interactome of the VAP Family of Proteins: An Overview​
    James, C. & Kehlenbach, R. H. ​ (2021) 
    Cells10(7) pp. 1780​.​ DOI: https://doi.org/10.3390/cells10071780 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article
    ​ ​Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import​
    Carlon-Andres, I.; Lagadec, F.; Pied, N.; Rayne, F.; Lafon, M.-E.; Kehlenbach, R. H.   & Wodrich, H.​ (2020) 
    Journal of Virology94(10).​ DOI: https://doi.org/10.1128/JVI.00164-20 
    Details  DOI 
  • 2020 Book Chapter
    ​ ​Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture​
    Chizhik, A. I.; Chizhik, A. M.; Ruhlandt, D.; Pfaff, J.; Karedla, N.; Gregor, I.& Kehlenbach, R. H.  et al.​ (2020)
    In:​Hancock, Ronald​ (Ed.), The Nucleus pp. 33​-45. (3. ed.). ​New York: ​Springer. DOI: https://doi.org/10.1007/978-1-0716-0763-3_4 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Overview
    ​ ​Into the basket and beyond: the journey of mRNA through the nuclear pore complex​
    Ashkenazy-Titelman, A.; Shav-Tal, Y. & Kehlenbach, R. H. ​ (2020) 
    Biochemical Journal477(1) pp. 23​-44​.​ DOI: https://doi.org/10.1042/BCJ20190132 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Probing the Environment of Emerin by Enhanced Ascorbate Peroxidase 2 (APEX2)-Mediated Proximity Labeling​
    Müller, M.; James, C.; Lenz, C. ; Urlaub, H.   & Kehlenbach, R. H. ​ (2020) 
    Cells9(3) pp. 605​.​ DOI: https://doi.org/10.3390/cells9030605 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article
    ​ ​The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia–associated NUP214 fusion proteins regulate Notch signaling​
    Kindermann, B.; Valkova, C.; Krämer, A.; Perner, B.; Engelmann, C.; Behrendt, L. & Kritsch, D. et al.​ (2019) 
    Journal of Biological Chemistry294(31) pp. 11741​-11750​.​ DOI: https://doi.org/10.1074/jbc.RA118.006357 
    Details  DOI 
  • 2019 Journal Article | Research Paper | 
    ​ ​Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane​
    James, C.; Müller, M.; Goldberg, M. W.; Lenz, C. ; Urlaub, H.   & Kehlenbach, R. H. ​ (2019) 
    Journal of Biological Chemistry294(44) pp. 16241​-16254​.​ DOI: https://doi.org/10.1074/jbc.RA118.007283 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Overview
    ​ ​The cargo spectrum of nuclear transport receptors​
    Baade, I.   & Kehlenbach, R. H ​ (2019) 
    Current Opinion in Cell Biology58 pp. 1​-7​.​ DOI: https://doi.org/10.1016/j.ceb.2018.11.004 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking​
    Wu, K.; Wang, L.; Chen, Y.; Pirooznia, M.; Singh, K.; Wälde, S. & Kehlenbach, R. H.  et al.​ (2018) 
    Journal of Cell Science131(22) pp. jcs221036​.​ DOI: https://doi.org/10.1242/jcs.221036 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Extensive Identification and In-depth Validation of Importin 13 Cargoes​
    Baade, I. ; Spillner, C.; Schmitt, K.; Valerius, O.   & Kehlenbach, R. H. ​ (2018) 
    Molecular & Cellular Proteomics17(7) pp. 1337​-1353​.​ DOI: https://doi.org/10.1074/mcp.RA118.000623 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1​
    Ederle, H.; Funk, C.; Abou-Ajram, C.; Hutten, S.; Funk, E. B. E.; Kehlenbach, R. H.   & Bailer, S. M. et al.​ (2018) 
    Scientific Reports8(1).​ DOI: https://doi.org/10.1038/s41598-018-25007-5 
    Details  DOI 
  • 2018 Journal Article
    ​ ​In Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication​
    Komatsu, T.; Quentin-Froignant, C.; Carlon-Andres, I.; Lagadec, F.; Rayne, F.; Ragues, J. & Kehlenbach, R. H.  et al.​ (2018) 
    Journal of Virology92(18).​ DOI: https://doi.org/10.1128/JVI.00795-18 
    Details  DOI 
  • 2017 Journal Article | Research Paper
    ​ ​Three-Dimensional Reconstruction of Nuclear Envelope Architecture Using Dual-Color Metal-Induced Energy Transfer Imaging​
    Chizhik, A. M. ; Ruhlandt, D.; Pfaff, J. ; Karedla, N. ; Chizhik, A. I. ; Gregor, I.   & Kehlenbach, R. H.  et al.​ (2017) 
    ACS Nano11(12) pp. 11839​-11846​.​ DOI: https://doi.org/10.1021/acsnano.7b04671 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A) + RNA Export​
    Port, S. A.; Mendes, A.; Valkova, C.; Spillner, C.; Fahrenkrog, B.; Kaether, C. & Kehlenbach, R. H. ​ (2016) 
    Journal of Biological Chemistry291(44) pp. 23068​-23083​.​ DOI: https://doi.org/10.1074/jbc.M116.735340 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Crystal structure of the 239 kDa nuclear export complex CRM1 - RanGTP - Snurportin1 - Nup214 - MBP​
    Ficner, R. ; Monecke, T. ; Port, S. A.; Weiß, M. S.; Kehlenbach, R. H.   & Dickmanns, A. ​ (2016) 
    Acta Crystallographica Section A Foundations and Advances72(a1) pp. s30​-s30​.​ DOI: https://doi.org/10.1107/S2053273316099526 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors​
    Landry-Voyer, A.-M.; Bilodeau, S.; Bergeron, D.; Dionne, K. L.; Port, S. A.; Rouleau, C. & Boisvert, F.-M. et al.​ (2016) 
    Molecular and Cellular Biology36(24) pp. 3019​-3032​.​ DOI: https://doi.org/10.1128/MCB.00303-16 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper
    ​ ​Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane​
    Pfaff, J. ; Monroy, J. R.; Jamieson, C.; Rajanala, K.; Vilardi, F.; Schwappach, B.   & Kehlenbach, R. H. ​ (2016) 
    Journal of Cell Science129(3) pp. 502​-516​.​ DOI: https://doi.org/10.1242/jcs.179333 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article
    ​ ​Nuclear Pore Complexes and Nucleocytoplasmic Transport​
    Dickmanns, A. ; Kehlenbach, R. H.   & Fahrenkrog, B.​ (2015) 
    International Review of Cell and Molecular Biology, pp. 171​-233​.​ DOI: https://doi.org/10.1016/bs.ircmb.2015.07.010 
    Details  DOI 
  • 2015 Journal Article | Research Paper
    ​ ​Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex​
    Monecke, T. ; Dickmanns, A. ; Weiss, M. S.; Port, S. A.; Kehlenbach, R. H.   & Ficner, R. ​ (2015) 
    Acta Crystallographica Section F Structural Biology Communications71 pp. 1481​-1487​.​ DOI: https://doi.org/10.1107/S2053230X15021524 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export​
    Port, S. A.; Monecke, T. ; Dickmanns, A. ; Spillner, C.; Hofele, R.; Urlaub, H.   & Ficner, R.  et al.​ (2015) 
    Cell Reports13(4) pp. 690​-702​.​ DOI: https://doi.org/10.1016/j.celrep.2015.09.042 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​MD Simulations and FRET Reveal an Environment: Sensitive Conformational Plasticity of Importin-beta​
    Halder, K.; Doelker, N.; Van, Q. ; Gregor, I. ; Dickmanns, A. ; Baade, I.   & Kehlenbach, R. H.  et al.​ (2015) 
    Biophysical Journal109(2) pp. 277​-286​.​ DOI: https://doi.org/10.1016/j.bpj.2015.06.014 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article
    ​ ​Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy​
    Schulz, O.; Pieper, C. ; Clever, M.; Pfaff, J. ; Ruhlandt, A. ; Kehlenbach, R. H.   & Wouters, F. S.  et al.​ (2013) 
    Proceedings of the National Academy of Sciences of the United States of America110(52) pp. 21000​-21005​.​ DOI: https://doi.org/10.1073/pnas.1315858110 
    Details  DOI 

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