Prof. Dr. Johannes Kornhuber

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  • 2022 Journal Article | 
    ​ ​Polcher, Alexandra, Steffen Wolfsgruber, Oliver Peters, Lutz Frölich, Jens Wiltfang, Johannes Kornhuber, Michael Hüll et al. "A Comparison of Operational Definitions for Mild Cognitive Impairment​." ​Journal of Alzheimer's Disease ​88, no. 4 (2022): ​1663​-1678​. ​https://doi.org/10.3233/JAD-215548.
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  • 2022 Journal Article | 
    ​ ​Hellmann-Regen, Julian, Vera Clemens, Michael Grözinger, Johannes Kornhuber, Andreas Reif, David Prvulovic, Roberto Goya-Maldonado et al. "Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression​." ​JAMA Network Open ​5, no. 9 (2022): ​e2230367​. ​https://doi.org/10.1001/jamanetworkopen.2022.30367.
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  • 2021 Journal Article
    ​ ​Carpinteiro, Alexander, Barbara Gripp, Markus Hoffmann, Stefan Pöhlmann, Nicolas Hoertel, Michael J. Edwards, Markus Kamler, Johannes Kornhuber, Katrin Anne Becker, and Erich Gulbins. "Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells​." ​Journal of Biological Chemistry ​296 (2021): ​S0021925821004907​. ​https://doi.org/10.1016/j.jbc.2021.100701.
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  • 2021 Journal Article
    ​ ​Ophey, Anja, Steffen Wolfsgruber, Sandra Roeske, Alexandra Polcher, Annika Spottke, Lutz Frölich, Michael Hüll et al. "Cognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments​." ​Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring ​13, no. 1 (2021): . ​https://doi.org/10.1002/dad2.12223.
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  • 2021 Journal Article | 
    ​ ​Oberstein, Timo Jan, Janine Utz, Philipp Spitzer, Hans Wolfgang Klafki, Jens Wiltfang, Piotr Lewczuk, Johannes Kornhuber, and Juan Manuel Maler. "The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes​." ​Frontiers in Molecular Neuroscience ​13 (2021): . ​https://doi.org/10.3389/fnmol.2020.615740.
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  • 2020 Journal Article
    ​ ​Rhein, Cosima, Christiane Mühle, Bernd Lenz, Tanja Richter-Schmidinger, Georgios Kogias, Fernando Boix, Anbarasu Lourdusamy et al. "Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly​." ​Brain Research Bulletin ​161 (2020): ​13​-20​. ​https://doi.org/10.1016/j.brainresbull.2020.05.001.
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  • 2020 Journal Article | 
    ​ ​Kleineidam, Luca, Vincent Chouraki, Tomasz Próchnicki, Sven J. van der Lee, Laura Madrid-Márquez, Holger Wagner-Thelen, Ilker Karaca et al. "PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment​." ​Acta Neuropathologica ​139, no. 6 (2020): ​1025​-1044​. ​https://doi.org/10.1007/s00401-020-02138-6.
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  • 2020 Journal Article
    ​ ​Maier, Franziska, Annika Spottke, Jan-Philipp Bach, Claudia Bartels, Katharina Buerger, Richard Dodel, Andreas Fellgiebel et al. "Bupropion for the Treatment of Apathy in Alzheimer Disease​." ​JAMA Network Open ​3, no. 5 (2020): ​e206027​. ​https://doi.org/10.1001/jamanetworkopen.2020.6027.
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  • 2020 Journal Article
    ​ ​Fuentes, Manuel, Arne Klostermann, Luca Kleineidam, Chris Bauer, Johannes Schuchhardt, Wolfgang Maier, Frank Jessen et al. "Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer’s Disease Dementia via Lead-Lag Analysis​." ​Journal of Alzheimer's Disease ​76, no. 3 (2020): ​1005​-1015​. ​https://doi.org/10.3233/JAD-200230.
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  • 2019 Journal Article | 
    ​ ​Albrecht, Franziska, Karsten Mueller, Tommaso Ballarini, Leonie Lampe, Janine Diehl-Schmid, Klaus Fassbender, Klaus Fliessbach et al. "Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging​." ​Cortex ​117 (2019): ​33​-40​. ​https://doi.org/10.1016/j.cortex.2019.02.015.
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  • 2019 Journal Article
    ​ ​van Maurik, Ingrid S, Stephanie J Vos, Isabelle Bos, Femke H Bouwman, Charlotte E Teunissen, Philip Scheltens, Frederik Barkhof et al. "Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study​." ​The Lancet Neurology ​18, no. 11 (2019): ​1034​-1044​. ​https://doi.org/10.1016/S1474-4422(19)30283-2.
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  • 2019 Journal Article | Research Paper | 
    ​ ​Jain, Gaurav, Anne Stuendl, Pooja Rao, Tea Berulava, Tonatiuh Pena Centeno, Lalit Kaurani, Susanne Burkhardt et al. "A combined miRNA–piRNA signature to detect Alzheimer’s disease​." ​Translational Psychiatry ​9, no. 1 (2019): . ​https://doi.org/10.1038/s41398-019-0579-2.
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  • 2018 Journal Article
    ​ ​Espinosa, Ana, Begoña Hernández-Olasagarre, Sonia Moreno-Grau, Luca Kleineidam, Stefanie Heilmann-Heimbach, Isabel Hernández, Steffen Wolfsgruber et al. "Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes​." ​Frontiers in Aging Neuroscience ​10 (2018): . ​https://doi.org/10.3389/fnagi.2018.00340.
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  • 2018 Journal Article
    ​ ​Steinacker, Petra, Sarah Anderl-Straub, Janine Diehl-Schmid, Elisa Semler, Ingo Uttner, Christine A.F. von Arnim, Henryk Barthel et al. "Serum neurofilament light chain in behavioral variant frontotemporal dementia​." ​Neurology ​91, no. 15 (2018): ​e1390​-e1401​. ​https://doi.org/10.1212/WNL.0000000000006318.
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  • 2018 Journal Article
    ​ ​Lewczuk, Piotr, Peter Riederer, Sid E. O’Bryant, Marcel M. Verbeek, Bruno Dubois, Pieter Jelle Visser, Kurt A. Jellinger et al. "Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​." ​The World Journal of Biological Psychiatry ​19, no. 4 (2018): ​244​-328​. ​https://doi.org/10.1080/15622975.2017.1375556.
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  • 2018 Journal Article
    ​ ​Schroeter, Matthias L., Sarah Pawelke, Sandrine Bisenius, Jana Kynast, Katharina Schuemberg, Maryna Polyakova, Sarah Anderl-Straub et al. "A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests​." ​Frontiers in Aging Neuroscience ​10 (2018): . ​https://doi.org/10.3389/fnagi.2018.00011.
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  • 2018 Journal Article
    ​ ​Mattsson, Niklas, Colin Groot, Willemijn J. Jansen, Susan M. Landau, Victor L. Villemagne, Sebastiaan Engelborghs, Mark M. Mintun et al. "Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease​." ​Alzheimer's & Dementia ​14, no. 7 (2018): ​913​-924​. ​https://doi.org/10.1016/j.jalz.2018.02.009.
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  • 2018 Journal Article | 
    ​ ​Denk, Johannes, Felix Oberhauser, Johannes Kornhuber, Jens Wiltfang, Klaus Fassbender, Matthias L. Schroeter, Alexander E. Volk et al. "Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls​." ​PLoS One ​13, no. 5 (2018): ​e0197329​. ​https://doi.org/10.1371/journal.pone.0197329.
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  • 2018 Journal Article | 
    ​ ​Semler, Elisa, Sarah Anderl-Straub, Ingo Uttner, Janine Diehl-Schmid, Adrian Danek, Beate Einsiedler, Klaus Fassbender et al. "A language-based sum score for the course and therapeutic intervention in primary progressive aphasia​." ​Alzheimer's Research & Therapy ​10, no. 1 (2018): . ​https://doi.org/10.1186/s13195-018-0345-3.
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  • 2017 Journal Article | 
    ​ ​Frölich, Lutz, Oliver Peters, Piotr Lewczuk, Oliver Gruber, Stefan J. Teipel, Hermann J. Gertz, Holger Jahn et al. "Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia​." ​Alzheimer's Research & Therapy ​9, no. 1 (2017): ​84​. ​https://doi.org/10.1186/s13195-017-0301-7.
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  • 2017 Journal Article
    ​ ​Bos, Isabelle, Stephanie J. Vos, Lutz Frölich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters et al. "The frequency and influence of dementia risk factors in prodromal Alzheimer's disease​." ​Neurobiology of Aging ​56 (2017): ​33​-40​. ​https://doi.org/10.1016/j.neurobiolaging.2017.03.034.
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  • 2017 Journal Article
    ​ ​Steinacker, Petra, Elisa Semler, Sarah Anderl-Straub, Janine Diehl-Schmid, Matthias L. Schroeter, Ingo Uttner, Hans Foerstl et al. "Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias​." ​Neurology ​88, no. 10 (2017): ​961​-969​. ​https://doi.org/10.1212/WNL.0000000000003688.
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  • 2017 Journal Article
    ​ ​Schmitt, Andrea, Daniel Martins-de-Souza, Schahram Akbarian, Juliana S. Cassoli, Hannelore Ehrenreich, Andre Fischer, Alfred Fonteh et al. "Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms​." ​The World journal of Biological Psychiatry ​18, no. 5 (2017): ​330​-356​. ​https://doi.org/10.1080/15622975.2016.1224929.
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  • 2017 Journal Article
    ​ ​Wolfsgruber, Steffen, Alexandra Polcher, Alexander Koppara, Luca Kleineidam, Lutz Frölich, Oliver Peters, Michael Hüll et al. "Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment​." ​Journal of Alzheimer's Disease ​58, no. 3 (2017): ​939​-950​. ​https://doi.org/10.3233/JAD-161252.
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  • 2016 Journal Article
    ​ ​Louwersheimer, Eva, Steffen Wolfsgruber, Ana Espinosa, André Lacour, Stefanie Heilmann-Heimbach, Montserrat Alegret, Isabel Hernández et al. "Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment​." ​Alzheimer's & Dementia ​12, no. 8 (2016): ​872​-881​. ​https://doi.org/10.1016/j.jalz.2016.01.006.
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  • 2016 Journal Article
    ​ ​Koppara, Alexander, Steffen Wolfsgruber, Luca Kleineidam, Klaus Schmidtke, Lutz Frölich, Alexander Kurz, Stefanie Schulz et al. "The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment​." ​Journal of Alzheimer's Disease ​49, no. 2 (2016): ​547​-560​. ​https://doi.org/10.3233/jad-150257.
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  • 2016 Journal Article
    ​ ​Lelental, Natalia, Sebastian Brandner, Olga Kofanova, Kaj Blennow, Henrik Zetterberg, Ulf Andreasson, Sebastiaan Engelborghs et al. "Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics​." ​Journal of Alzheimer's Disease ​52, no. 1 (2016): ​51​-64​. ​https://doi.org/10.3233/jad-150883.
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  • 2016 Journal Article
    ​ ​Bey, Katharina, Steffen Wolfsgruber, Ilker Karaca, Holger Wagner, Roy Lardenoije, Julian Becker, Esther Milz et al. "No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment​." ​Epigenomics ​8, no. 5 (2016): ​593​-598​. ​https://doi.org/10.2217/epi-2015-0014.
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  • 2016 Journal Article | 
    ​ ​Lacour, A., A. Espinosa, E. Louwersheimer, S. Heilmann, I. Hernández, S. Wolfsgruber, V. Fernández et al. "Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment​." ​Molecular Psychiatry ​22, no. 1 (2016): ​153​-160​. ​https://doi.org/10.1038/mp.2016.18.
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  • 2016 Journal Article | 
    ​ ​Peters, Oliver, Isabella Heuser, Lutz Frölich, Eckart Rüther, Otto Rienhoff, Johannes Kornhuber, Jens Wiltfang, and Wolfgang Maier. "Das Kompetenznetz Demenzen: ​Erfolge und Ausblicke​." ​Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz ​59, no. 4 (2016): ​438​-443​. ​https://doi.org/10.1007/s00103-016-2314-y.
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  • 2016 Journal Article | 
    ​ ​Teipel, Stefan J., Theresa Raiser, Lina Riedl, Isabelle Riederer, Matthias L. Schroeter, Sandrine Bisenius, Anja Schneider et al. "Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia​." ​Cortex ​83 (2016): ​124​-135​. ​https://doi.org/10.1016/j.cortex.2016.07.004.
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  • 2015 Journal Article
    ​ ​Wolfsgruber, Steffen, Frank Jessen, Alexander Koppara, Luca Kleineidam, Klaus Schmidtke, Lutz Frölich, Alexander Kurz et al. "Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI​." ​Neurology ​84, no. 12 (2015): ​1261​-1268​. ​https://doi.org/10.1212/wnl.0000000000001399.
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  • 2015 Journal Article
    ​ ​Lewczuk, Piotr, Johannes Kornhuber, Jon B. Toledo, John Q. Trojanowski, Malgorzata Knapik-Czajka, Oliver Peters, Jens Wiltfang, and Leslie M. Shaw. "Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer’s Disease in Pre-Dementia Subjects​." ​Journal of Alzheimer's Disease ​48, no. 2 (2015): ​433​-441​. ​https://doi.org/10.3233/jad-150342.
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  • 2015 Journal Article | 
    ​ ​Morgen, Katrin, Michael Schneider, Lutz Frölich, Heike Tost, Michael M. Plichta, Heike Kölsch, Fabian Rakebrandt et al. "Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study​." ​Alzheimer's Research & Therapy ​7, no. 1 (2015): . ​https://doi.org/10.1186/s13195-015-0111-8.
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  • 2015 Journal Article
    ​ ​Vos, Stephanie J. B., Frans R. J. Verhey, Lutz Frölich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters et al. "Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage​." ​Brain ​138, no. 5 (2015): ​1327​-1338​. ​https://doi.org/10.1093/brain/awv029.
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  • 2015 Journal Article | 
    ​ ​Heilmann, Stefanie, Dmitriy Drichel, Jordi Clarimon, Victoria Fernández, André Lacour, Holger Wagner, Mathias Thelen et al. "PLD3 in non-familial Alzheimer's disease​." ​Nature ​520, no. 7545 (2015): ​E3​-E5​. ​https://doi.org/10.1038/nature14039.
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  • 2015 Journal Article
    ​ ​Popp, Julius, Steffen Wolfsgruber, Isabella Heuser, Oliver Peters, Michael Hüll, Johannes Schröder, Hans-Jürgen Möller et al. "Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type​." ​Neurobiology of Aging ​36, no. 2 (2015): ​601​-607​. ​https://doi.org/10.1016/j.neurobiolaging.2014.10.031.
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  • 2014 Journal Article | 
    ​ ​Oberstein, Timo Jan, Philipp Spitzer, Hans-Wolfgang Klafki, Philipp Linning, Florian Neff, Hans-Joachim Knölker, Piotr Lewczuk, Jens Wiltfang, Johannes Kornhuber, and Juan Manuel Maler. "Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides​." ​Neurobiology of Disease ​73 (2014): ​24​-35​. ​https://doi.org/10.1016/j.nbd.2014.08.031.
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  • 2014 Journal Article
    ​ ​Kornhuber, Johannes, Andreas Schultz, Jens Wiltfang, Ingolf Meineke, Christoph H. Gleiter, Robert Zöchling, Karl-Werner Boissl, Friedrich Leblhuber, and Peter Riederer. "Persistence of Haloperidol in Human Brain Tissue​." ​The American Journal of Psychiatry ​156, no. 6 (2014): ​885​-890​. ​https://doi.org/10.1176/ajp.156.6.885.
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  • 2014 Journal Article
    ​ ​Ramirez, Alfredo, Wiesje M. van der Flier, Christine Herold, David Ramonet, Stefanie Heilmann, Piotr Lewczuk, Julius Popp et al. "SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease​." ​Human Molecular Genetics ​23, no. 24 (2014): ​6644​-6658​. ​https://doi.org/10.1093/hmg/ddu372.
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  • 2014 Journal Article
    ​ ​Louwersheimer, Eva, Alfredo Ramirez, Carlos Cruchaga, Tim Becker, Johannes Kornhuber, Oliver Peters, Stefanie Heilmann et al. "The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease​." ​Neurobiology of Aging ​36, no. 3 (2014): ​1605.e13​-1605.e20​. ​https://doi.org/10.1016/j.neurobiolaging.2014.12.007.
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  • 2012 Journal Article
    ​ ​Otto, Markus, Hermann Esselmann, W. Schulz-Schaeffer, Manuela Neumann, A. Schröter, P. Ratzka, L. Cepek et al. "Decreased  β-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease​." ​Neurology ​54, no. 5 (2012): ​1099​-1102​. ​https://doi.org/10.1212/wnl.54.5.1099.
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  • 2012 Book Chapter
    ​ ​Kornhuber, J., and Jens Wiltfang. "The role of glutamate in dementia​." ​In Ageing and Dementia, edited by Kurt Jellinger, F. Fazekas, Manfred Windisch​. ​​Vienna: ​Springer, ​2012. https://doi.org/10.1007/978-3-7091-6467-9_24.
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  • 2012 Journal Article | Research Paper
    ​ ​Tischbirek, Carsten H., Eva M. Wenzel, Fang Zheng, Tobias Huth, Davide Amato, Stefan Trapp, Annette Denker et al. "Use-Dependent Inhibition of Synaptic Transmission by the Secretion of Intravesicularly Accumulated Antipsychotic Drugs​." ​Neuron ​74, no. 5 (2012): ​830​-844​. ​https://doi.org/10.1016/j.neuron.2012.04.019.
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  • 2011 Book Chapter
    ​ ​Kornhuber, Johannes, Iris Gundacker, Manuel Maler, Markus Otto, and Jens Wiltfang. "Neurotransmitterveränderungen bei der Alzheimer Demenz​." ​In Alzheimer Demenz - Grundlagen, Klinik und Therapie, edited by Hans Förstl, Horst Bickel, Alexander Kurz​. ​​Berlin, Heidelberg: ​Springer, ​2011. https://doi.org/10.1007/978-3-642-60228-3_5.
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  • 2011 Journal Article | Research Paper
    ​ ​Welzel, Oliver, Andreas Wolfram Henkel, Armin M. Stroebel, Jasmin Jung, Carsten H. Tischbirek, Katrin Ebert, Johannes Kornhuber, S. O. Rizzoli, and Teja Wolfgang Groemer. "Systematic Heterogeneity of Fractional Vesicle Pool Sizes and Release Rates of Hippocampal Synapses​." ​Biophysical Journal ​100, no. 3 (2011): ​593​-601​. ​https://doi.org/10.1016/j.bpj.2010.12.3706.
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  • 2010 Journal Article
    ​ ​Richter-Schmidinger, Tanja, Panagiotis Alexopoulos, Marco Horn, Sebastian Maus, Martin Reichel, Cosima Rhein, Piotr Lewczuk et al. "Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults​." ​Journal of Neural Transmission ​118, no. 2 (2010): ​249​-257​. ​https://doi.org/10.1007/s00702-010-0539-8.
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  • 2010 Journal Article
    ​ ​Alexopoulos, Panagiotis, Antje Ebert, Tanja Richter-Schmidinger, E. Schöll, B. Natale, C. A. Aguilar, P. Gourzis et al. "Validation of the German Revised Addenbrooke’s Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer’s Disease and Frontotemporal Lobar Degeneration​." ​Dementia and Geriatric Cognitive Disorders ​29, no. 5 (2010): ​448​-456​. ​https://doi.org/10.1159/000312685.
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  • 2010 Journal Article
    ​ ​Alexopoulos, Panagiotis, S. Lehrl, Tanja Richter-Schmidinger, A. Kreusslein, T. Hauenstein, F. Bayerl, P. Jung et al. "Short-term influence of elevation of plasma homocysteine levels on cognitive function in young healthy adults​." ​The Journal of Nutrition, Health & Aging ​14, no. 4 (2010): ​283​-287​. ​https://doi.org/10.1007/s12603-010-0062-5.
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  • 2009 Journal Article
    ​ ​Alexopoulos, Panagiotis, Florian Günther, Julius Popp, Frank Jessen, Oliver Peters, Stefanie Wolf, Thomas Kneib et al. "PLASMA HOMOCYSTEINE AND CEREBROSPINAL FLUID NEURODEGENERATION BIOMARKERS IN MILD COGNITIVE IMPAIRMENT AND DEMENTIA​." ​Journal of the American Geriatrics Society ​57, no. 4 (2009): ​737​-739​. ​https://doi.org/10.1111/j.1532-5415.2009.02212.x.
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  • 2008 Journal Article
    ​ ​Kornhuber, Johannes, Manuel Maler, Jens Wiltfang, Stefan Bleich, Detlef Degner, and Eckart Rüther. "Neuronale Kaliumkanalöffnung durch Flupirtin: ​Opening of Neuronal K+ Channels by Flupirtine​." ​Fortschritte der Neurologie · Psychiatrie ​67, no. 10 (2008): ​466​-475​. ​https://doi.org/10.1055/s-2007-994997.
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  • 2004 Journal Article
    ​ ​Esselmann, Hermann, J. M. Maler, N. Kunz, Markus Otto, S. Paul, Piotr Lewczuk, Eckart Rüther, Johannes Kornhuber, and Jens Wiltfang. "Lithium Decreases Secretion of Aβ1–42 and C-Truncated Species Aβ1–37/38/39/40 in Chicken Telencephalic Cultures but Specifically Increases Intracellular Aβ1–38​." ​Neurodegenerative Diseases ​1, no. 4-5 (2004): ​236​-241​. ​https://doi.org/10.1159/000080992.
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  • 2004 Journal Article
    ​ ​Bibl, Mirko, Hermann Esselmann, Markus Otto, Piotr Lewczuk, Lukas Cepek, Eckart Rüther, Johannes Kornhuber, and Jens Wiltfang. "Cerebrospinal fluid amyloidβ peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloidβ peptides​." ​ELECTROPHORESIS ​25, no. 17 (2004): ​2912​-2918​. ​https://doi.org/10.1002/elps.200305992.
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  • 2004 Journal Article
    ​ ​Lewczuk, Piotr, Hermann Esselmann, Mirko Bibl, Sabine Paul, Jana Svitek, Johannes Miertschischk, Robert Meyrer et al. "Electrophoretic separation of amyloid β peptides in plasma​." ​ELECTROPHORESIS ​25, no. 20 (2004): ​3336​-3343​. ​https://doi.org/10.1002/elps.200406068.
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  • 2004 Journal Article
    ​ ​Lewczuk, Piotr, Hermann Esselmann, Mirko Bibl, Georg Beck, Juan Manuel Maler, Markus Otto, Johannes Kornhuber, and Jens Wiltfang. "Tau Protein Phosphorylated at Threonine 181 in CSF as a Neurochemical Biomarker in Alzheimer's Disease: ​Original Data and Review of the Literature​." ​Journal of Molecular Neuroscience ​23, no. 1-2 (2004): ​115​-122​. ​https://doi.org/10.1385/jmn:23:1-2:115.
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  • 2004 Journal Article
    ​ ​Lewczuk, Piotr, Hermann Esselmann, Teja Wolfgang Groemer, Mirko Bibl, Juan Manuel Maler, Petra Steinacker, Markus Otto, Johannes Kornhuber, and Jens Wiltfang. "Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease​." ​Biological Psychiatry ​55, no. 5 (2004): ​524​-530​. ​https://doi.org/10.1016/j.biopsych.2003.10.014.
    Details  DOI  PMID  PMC 
  • 2003 Journal Article
    ​ ​Wiltfang, Jens, Hermann Esselmann, M. Bibl, A. Smirnov, Markus Otto, S. Paul, B. Schmidt et al. "Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation​." ​Journal of Neurochemistry ​81, no. 3 (2003): ​481​-496​. ​https://doi.org/10.1046/j.1471-4159.2002.00818.x.
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  • 2003 Journal Article
    ​ ​Maler, J. M., W. Seifert, G. Hüther, J. Wiltfang, E. Rüther, J. Kornhuber, and Stefan Bleich. "Homocysteine induces cell death of rat astrocytes in vitro​." ​Neuroscience Letters ​347, no. 2 (2003): ​85​-88​. ​https://doi.org/10.1016/s0304-3940(03)00655-4.
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  • 2002 Journal Article
    ​ ​Kornhuber, J., S. Bleich, J. Wiltfang, M. Maler, and C. G. Parsons. "Flupirtine shows functional NMDA receptor antagonism by enhancing Mg 2+ block via activation of voltage independent potassium channels​." ​Journal of Neural Transmission ​106, no. 9 (2002): ​857​-867​. ​https://doi.org/10.1007/s007020050206.
    Details  DOI 
  • 2002 Journal Article
    ​ ​Bleich, Stefan, K. Bleich, Jens Wiltfang, Juan Manuel Maler, and Johannes Kornhuber. "Glutamaterge Neurotransmission bei Schizophrenien​." ​Fortschritte der Neurologie · Psychiatrie ​69, no. SH2 (2002): ​56​-61​. ​https://doi.org/10.1055/s-2001-16531.
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  • 2001 Journal Article
    ​ ​Demling, J. H., Jens Wiltfang, and Johannes Kornhuber. "Neue Behandlungsparadigmen der Demenz. Rechtzeitig erkennen - und dann?​." ​DNP - Neurologe und Psychiater ​4 (2001): . ​
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  • 2001 Journal Article
    ​ ​Wiltfang, Jens, Hermann Esselmann, Juan Manuel Maler, Stefan Bleich, Gerald Hüther, and Johannes Kornhuber. "Molecular Biology of Alzheimer’s Dementia and Its Clinical Relevance to Early Diagnosis and New Therapeutic Strategies​." ​Gerontology ​47, no. 2 (2001): ​65​-71​. ​https://doi.org/10.1159/000052775.
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  • 2000 Journal Article
    ​ ​Bleich, S., D. Degner, J. Wiltfang, J. M. Maler, P. Niedmann, S. Cohrs, A. Mangholz et al. "Elevated Homocysteine Levels in Alcohol Withdrawal​." ​Alcohol and Alcoholism ​35, no. 4 (2000): ​351​-354​. ​https://doi.org/10.1093/alcalc/35.4.351.
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  • 2000 Journal Article
    ​ ​Bleich, S., S. Kropp, D. Degner, I. Zerr, J. Pilz, C. H. Gleiter, M. Otto et al. "Creutzfeldt-Jakob disease and oxidative stress​." ​Acta Neurologica Scandinavica ​101, no. 5 (2000): ​332​-334​. ​https://doi.org/10.1034/j.1600-0404.2000.9s290a.x.
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Otto, M., J. Wiltfang, S. Poser, and J. Kornhuber. "Tau Protein: Ein potentieller biologischer Indikator zur Früherkennung der Alzheimer-Krankheit: ​Anmerkung zur Arbeit von K. Buch et al. Nervenarzt (1998) 69: 379–385​." ​Der Nervenarzt ​70, no. 7 (1999): ​668​-670​. ​https://doi.org/10.1007/s001150050494.
    Details  DOI 
  • 1999 Journal Article
    ​ ​Esselmann, Hermann, Jens Wiltfang, and Johannes Kornhuber. "Der NMDA-Rezeptor: ein Ionenkanal mit zwei Gesichtern​." ​Neurotransmitter ​2 (1999): . ​
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  • 1999 Book Chapter
    ​ ​Kornhuber, Johannes, and Jens Wiltfang. "Amantadin​." ​In Parkinsonmittel und Antidementiva, edited by P. von Riederer, G. Laux, W. Poldinger​, 261​-286​. ​Vol. 5 of Neuro-Psychopharmaka - Ein Therapie-Handbuch. ​Wien: ​Springer, ​1999. 
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  • 1999 Journal Article
    ​ ​Bleich, S., K. Spilker, C. Kurth, D. Degner, M. Quintela-Schneider, K. Javaheripour, E. Rüther, J. Kornhuber, and J. G. Wiltfang. "Oxidative stress and an altered methionine metabolism in alcoholism​." ​Neuroscience Letters ​293, no. 3 (1999): ​171​-174​. ​https://doi.org/10.1016/s0304-3940(00)01505-6.
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Kornhuber, Johannes, Kurt Jellinger, Jens Wiltfang, Fritz Leblhuber, and Peter Riederer. "The N-methyl-D-aspartate receptor channel blocker amantadine does not cause histopathological alterations in human brain tissue​." ​Acta Neuropathologica ​98, no. 1 (1999): ​85​-90​. ​https://doi.org/10.1007/s004010051054.
    Details  DOI  PMID  PMC 
  • 1999 Journal Article
    ​ ​Wiltfang, J., M. Otto, H. C. Baxter, M. Bodemer, P. Steinacker, E. Bahn, I. Zerr et al. "Isoform Pattern of 14-3-3 Proteins in the Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease​." ​Journal of Neurochemistry ​73, no. 6 (1999): ​2485​-2490​. ​https://doi.org/10.1046/j.1471-4159.1999.0732485.x.
    Details  DOI  PMID  PMC 
  • 1998 Journal Article
    ​ ​Kornhuber, Johannes, Jens Wiltfang, Hayrettin Tumani, and Eckart Rüther. "Was wird aus Gedächtnisstörungen​." ​Psycho ​12 (1998): . ​
    Details 
  • 1998 Journal Article
    ​ ​Wiltfang, J., W. Nolte, K. Weißenborn, J. Kornhuber, and E. Rüther. "Psychiatric Aspects of Portal-Systemic Encephalopathy​." ​Metabolic Brain Disease ​13, no. 4 (1998): ​379​-389​. ​https://doi.org/10.1023/a:1020697127718.
    Details  DOI 
  • 1998 Journal Article
    ​ ​Wiltfang, Jens, Markus Otto, and Johannes Kornhuber. "Labordiagnostik der Alzheimer-Demenz​." ​Psycho ​12 (1998): . ​
    Details 

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