Prof. Dr. Piotr Lewczuk

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  • 2022 Journal Article | With Fulltext​ | 
    ​ ​A Comparison of Operational Definitions for Mild Cognitive Impairment​
    Polcher, A.; Wolfsgruber, S.; Peters, O.; Frölich, L.; Wiltfang, J. ; Kornhuber, J.   & Hüll, M. et al.​ (2022) 
    Journal of Alzheimer's Disease88(4) pp. 1663​-1678​.​ DOI: 
    Details  DOI 
  • 2021 Journal Article | With Fulltext​ | 
    ​ ​The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes​
    Oberstein, T. J.; Utz, J.; Spitzer, P.; Klafki, H. W. ; Wiltfang, J. ; Lewczuk, P.   & Kornhuber, J.  et al.​ (2021) 
    Frontiers in Molecular Neuroscience13.​ DOI: 
    Details  DOI 
  • 2020 Journal Article | With Fulltext​ | 
    ​ ​PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment​
    Kleineidam, L.; Chouraki, V.; Próchnicki, T.; van der Lee, S. J.; Madrid-Márquez, L.; Wagner-Thelen, H. & Karaca, I. et al.​ (2020) 
    Acta Neuropathologica139(6) pp. 1025​-1044​.​ DOI: 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​
    Lewczuk, P. ; Riederer, P.; O’Bryant, S. E.; Verbeek, M. M.; Dubois, B.; Visser, P. J. & Jellinger, K. A. et al.​ (2018) 
    The World Journal of Biological Psychiatry19(4) pp. 244​-328​.​ DOI: 
    Details  DOI 
  • 2018 Journal Article | With Fulltext​ | 
    ​ ​White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation​
    Teunissen, C. E.; Otto, M. ; Engelborghs, S.; Herukka, S.-K.; Lehmann, S.; Lewczuk, P.   & Lleó, A. et al.​ (2018) 
    Alzheimer's Research & Therapy10(1).​ DOI: 
    Details  DOI 
  • 2017 Journal Article | With Fulltext​ | 
    ​ ​Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia​
    Frölich, L.; Peters, O.; Lewczuk, P. ; Gruber, O. ; Teipel, S. J.; Gertz, H. J. & Jahn, H. et al.​ (2017) 
    Alzheimer's Research & Therapy9(1) art. 84​.​ DOI: 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment​
    Wolfsgruber, S.; Polcher, A.; Koppara, A.; Kleineidam, L.; Frölich, L.; Peters, O. & Hüll, M. et al.​ (2017) 
    Journal of Alzheimer's Disease58(3) pp. 939​-950​.​ DOI: 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics​
    Lelental, N.; Brandner, S.; Kofanova, O.; Blennow, K.; Zetterberg, H.; Andreasson, U. & Engelborghs, S. et al.​ (2016) 
    Journal of Alzheimer's Disease52(1) pp. 51​-64​.​ DOI: 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Biomarker bei Demenzen und anderen neurodegenerativen Erkrankungen​
    Wiltfang, J. ; Lewczuk, P.   & Otto, M. ​ (2016) 
    Der Nervenarzt87(12) pp. 1305​-1309​.​ DOI: 
    Details  DOI 
  • 2015 Journal Article
    ​ ​Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer’s Disease in Pre-Dementia Subjects​
    Lewczuk, P. ; Kornhuber, J. ; Toledo, J. B.; Trojanowski, J. Q.; Knapik-Czajka, M.; Peters, O. & Wiltfang, J.  et al.​ (2015) 
    Journal of Alzheimer's Disease48(2) pp. 433​-441​.​ DOI: 
    Details  DOI 
  • 2015 Journal Article
    ​ ​Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type​
    Popp, J.; Wolfsgruber, S.; Heuser, I.; Peters, O.; Hüll, M.; Schröder, J. & Möller, H.-J. et al.​ (2015) 
    Neurobiology of Aging36(2) pp. 601​-607​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article
    ​ ​SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease​
    Ramirez, A.; van der Flier, W. M.; Herold, C.; Ramonet, D.; Heilmann, S.; Lewczuk, P.   & Popp, J. et al.​ (2014) 
    Human Molecular Genetics23(24) pp. 6644​-6658​.​ DOI: 
    Details  DOI 
  • 2014 Journal Article | With Fulltext​ | 
    ​ ​Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides​
    Oberstein, T. J.; Spitzer, P.; Klafki, H.-W. ; Linning, P.; Neff, F.; Knölker, H.-J. & Lewczuk, P.  et al.​ (2014) 
    Neurobiology of Disease73 pp. 24​-35​.​ DOI: 
    Details  DOI 
  • 2010 Journal Article
    ​ ​Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults​
    Richter-Schmidinger, T.; Alexopoulos, P.; Horn, M.; Maus, S.; Reichel, M.; Rhein, C. & Lewczuk, P.  et al.​ (2010) 
    Journal of Neural Transmission118(2) pp. 249​-257​.​ DOI: 
    Details  DOI 
  • 2009 Journal Article
    Alexopoulos, P.; Günther, F.; Popp, J.; Jessen, F.; Peters, O.; Wolf, S. & Kneib, T.  et al.​ (2009) 
    Journal of the American Geriatrics Society57(4) pp. 737​-739​.​ DOI: 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Lithium Decreases Secretion of Aβ1–42 and C-Truncated Species Aβ1–37/38/39/40 in Chicken Telencephalic Cultures but Specifically Increases Intracellular Aβ1–38​
    Esselmann, H. ; Maler, J. M. ; Kunz, N. ; Otto, M. ; Paul, S. ; Lewczuk, P.   & Rüther, E.  et al.​ (2004) 
    Neurodegenerative Diseases1(4-5) pp. 236​-241​.​ DOI: 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Electrophoretic separation of amyloid β peptides in plasma​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Paul, S.; Svitek, J.; Miertschischk, J. & Meyrer, R. et al.​ (2004) 
    ELECTROPHORESIS25(20) pp. 3336​-3343​.​ DOI: 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Cerebrospinal fluid amyloidβ peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloidβ peptides​
    Bibl, M. ; Esselmann, H. ; Otto, M. ; Lewczuk, P. ; Cepek, L. ; Rüther, E.   & Kornhuber, J.  et al.​ (2004) 
    ELECTROPHORESIS25(17) pp. 2912​-2918​.​ DOI: 
    Details  DOI 
  • 2004 Journal Article
    ​ ​Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease​
    Lewczuk, P. ; Esselmann, H. ; Groemer, T. W.; Bibl, M. ; Maler, J. M. ; Steinacker, P.   & Otto, M.  et al.​ (2004) 
    Biological Psychiatry55(5) pp. 524​-530​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2004 Journal Article
    ​ ​Tau Protein Phosphorylated at Threonine 181 in CSF as a Neurochemical Biomarker in Alzheimer's Disease: ​Original Data and Review of the Literature​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Beck, G.; Maler, J. M. ; Otto, M.   & Kornhuber, J.  et al.​ (2004) 
    Journal of Molecular Neuroscience23(1-2) pp. 115​-122​.​ DOI: 
    Details  DOI  PMID  PMC 
  • 2003 Journal Article
    ​ ​Prothrombin Concentration in the Cerebrospinal Fluid Is Not Altered in Alzheimer's Disease​
    Lewczuk, P. ; Wiltfang, J. ; Lange, M.; Jahn, H. ; Reiber, H.   & Ehrenreich, H. ​ (2003) 
    Neurochemical Research24(12) pp. 1531​-1534​.​ DOI: 
    Details  DOI 
  • 2002 Journal Article
    ​ ​Endothelin B receptor deficiency augments neuronal damage upon exposure to hypoxia-ischemia in vivo​
    Siren, A. L. ; Lewczuk, P. ; Hasselblatt, M. ; Dembowski, C. ; Schilling, L. & Ehrenreich, H. ​ (2002) 
    Brain Research,(1) pp. 144​-149​.​
    Details  PMID  PMC 
  • 2002 Journal Article | Research Paper
    ​ ​Erythropoietin therapy for acute stroke is both safe and beneficial​
    Ehrenreich, H. ; Hasselblatt, M. ; Dembowski, C. ; Cepek, L. ; Lewczuk, P. ; Stiefel, M.   & Rustenbeck, H.-H.  et al.​ (2002) 
    Molecular Medicine8(8) pp. 495​-505​.​
  • 2001 Journal Article
    ​ ​Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress​
    Sirén, A.-L. ; Fratelli, M.; Brines, M.; Goemans, C.; Casagrande, S.; Lewczuk, P.   & Keenan, S. et al.​ (2001) 
    Proceedings of the National Academy of Sciences of the United States of America98(7) pp. 4044​-4049​.​ DOI: 
    Details  DOI 

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