Dirk Matthes

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  • 2022 | Journal Article | 
    ​ ​The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils​
    Antonschmidt, L.; Matthes, D. ; Dervişoğlu, R.; Frieg, B.; Dienemann, C. ; Leonov, A.   & Nimerovsky, E. et al.​ (2022) 
    Nature Communications, 13(1).​ DOI: https://doi.org/10.1038/s41467-022-32797-w 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Resolving the Atomistic Modes of Anle138b Inhibitory Action on Peptide Oligomer Formation​
    Matthes, D. ; Gapsys, V. ; Griesinger, C.   & de Groot, B. L. ​ (2017) 
    ASC Chemical Neuroscience, 8(12) pp. 2791​-2808​.​ DOI: https://doi.org/10.1021/acschemneuro.7b00325 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Global and Local Conformational Heterogeniety Governs the Pre-Nucleation Phase in Amyloidogenic Self-Assembly​
    Matthes, D. ; Gapsys, V. ; Brennecke, J. T. & de Groot, B. L. ​ (2016) 
    Biophysical Journal, 110(3) pp. 402a​.​ DOI: https://doi.org/10.1016/j.bpj.2015.11.2170 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase​
    Matthes, D. ; Gapsys, V. ; Brennecke, J. T. & de Groot, B. L. ​ (2016) 
    Scientific Reports, 6(1).​ DOI: https://doi.org/10.1038/srep33156 
    ​Details  DOI 
  • 2014 | Journal Article | 
    ​ ​Spontaneous Aggregation of the Insulin-Derived Steric Zipper Peptide VEALYL Results in Different Aggregation Forms with Common Features​
    Matthes, D. ; Daebel, V.; Meyenberg, K.; Riedel, D. ; Heim, G. ; Diederichsen, U.   & Lange, A. et al.​ (2014) 
    Journal of Molecular Biology, 426(2) pp. 362​-376​.​ DOI: https://doi.org/10.1016/j.jmb.2013.10.020 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations​
    Matthes, D. ; Gapsys, V.   & de Groot, B. L. ​ (2012) 
    Journal of Molecular Biology, 421(2-3) pp. 390​-416​.​ DOI: https://doi.org/10.1016/j.jmb.2012.02.004 
    ​Details  DOI 
  • 2011 | Journal Article
    ​ ​Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization​
    Matthes, D. ; Gapsys, V. ; Daebel, V. & de Groot, B. L. ​ (2011) 
    PLoS One, 6(5) pp. e19129​.​ DOI: https://doi.org/10.1371/journal.pone.0019129 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​The Spontaneous Aggregation of Steric Zipper Peptides Studied by Molecular Dynamics Simulations​
    Matthes, D.   & de Groot, B. L. ​ (2010) 
    Biophysical Journal, 98(3) pp. 650a​.​ DOI: https://doi.org/10.1016/j.bpj.2009.12.3561 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Inside Cover: Primary Steps of pH‐Dependent Insulin Aggregation Kinetics are Governed by Conformational Flexibility (ChemBioChem 11/2009)​
    Haas, J.; Vöhringer-Martinez, E.; Bögehold, A.; Matthes, D. ; Hensen, U.; Pelah, A. & Abel, B.  et al.​ (2009) 
    ChemBioChem, 10(11) pp. 1742​.​ DOI: https://doi.org/10.1002/cbic.200990042 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Primary Steps of pH-Dependent Insulin Aggregation Kinetics are Governed by Conformational Flexibility​
    Haas, J.; Vöhringer-Martinez, E.; Bögehold, A.; Matthes, D. ; Hensen, U.; Pelah, A. & Abel, B.  et al.​ (2009) 
    ChemBioChem, 10(11) pp. 1816​-1822​.​ DOI: https://doi.org/10.1002/cbic.200900266 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Secondary Structure Propensities in Peptide Folding Simulations: A Systematic Comparison of Molecular Mechanics Interaction Schemes​
    Matthes, D.   & de Groot, B. L. ​ (2009) 
    Biophysical Journal, 97(2) pp. 599​-608​.​ DOI: https://doi.org/10.1016/j.bpj.2009.04.061 
    ​Details  DOI 

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https://publications.goettingen-research-online.de URI: /cris/rp/rp10819
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