Steffen Pabel

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  • 2022 | Journal Article | 
    ​ ​Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions​
    Paulus, M. G.; Renner, K.; Nickel, A. G.; Brochhausen, C.; Limm, K.; Zügner, E. & Baier, M. J. et al.​ (2022) 
    Basic Research in Cardiology, 117(1).​ DOI: https://doi.org/10.1007/s00395-022-00949-0 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Effects of Atrial Fibrillation on the Human Ventricle​
    Pabel, S. ; Knierim, M.; Stehle, T.; Alebrand, F.; Paulus, M.; Sieme, M. & Herwig, M. et al.​ (2022) 
    Circulation Research, 130(7) pp. 994​-1010​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.121.319718 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Atrial Fibrillation Burden Specifically Determines Human Ventricular Cellular Remodeling​
    Körtl, T.; Stehle, T.; Riedl, D.; Trausel, J.; Rebs, S. ; Pabel, S.   & Paulus, M. et al.​ (2022) 
    JACC: Clinical Electrophysiology, 8(11) pp. 1357​-1366​.​ DOI: https://doi.org/10.1016/j.jacep.2022.07.016 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​A mechanistic rationale for the investigation of sodium–glucose co‐transporter 2 inhibitors in heart failure with preserved ejection fraction. Letter regarding the article ‘Baseline characteristics of patients with heart failure with preserved ejection fraction in the EMPEROR‐Preserved trial’​
    Pabel, S. ; Hamdani, N. & Sossalla, S. ​ (2021) 
    European Journal of Heart Failure,.​ DOI: https://doi.org/10.1002/ejhf.2091 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure​
    Bengel, P. ; Dybkova, N.; Tirilomis, P.; Ahmad, S. ; Hartmann, N. H. ; A. Mohamed, B. & Krekeler, M. C. et al.​ (2021) 
    Nature Communications, 12(1) art. 6586​.​ DOI: https://doi.org/10.1038/s41467-021-26690-1 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation​
    Kolijn, D.; Pabel, S. ; Tian, Y.; Lódi, M.; Herwig, M.; Carrizzo, A. & Zhazykbayeva, S. et al.​ (2020) 
    Cardiovascular Research, 117(2) pp. 495​-507​.​ DOI: https://doi.org/10.1093/cvr/cvaa123 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias​
    Pabel, S. ; Mustroph, J.; Stehle, T.; Lebek, S.; Dybkova, N.; Keyser, A. & Rupprecht, L. et al.​ (2020) 
    Europace, 22(7) pp. 1111​-1118​.​ DOI: https://doi.org/10.1093/europace/euaa079 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice​
    Pabel, S. ; Ahmad, S. ; Tirilomis, P.; Stehle, T.; Mustroph, J.; Knierim, M. & Dybkova, N. et al.​ (2020) 
    Basic Research in Cardiology, 115(2).​ DOI: https://doi.org/10.1007/s00395-020-0780-8 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy​
    Ahmad, S. ; Tirilomis, P.; Pabel, S. ; Dybkova, N.; Hartmann, N. ; Molina, C. E.   & Tirilomis, T.  et al.​ (2019) 
    ESC Heart Failure, 6(1) pp. 154​-163​.​ DOI: https://doi.org/10.1002/ehf2.12378 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes​
    Mustroph, J.; Wagemann, O.; Lücht, C. M.; Trum, M.; Hammer, K. P.; Sag, C. M. & Lebek, S. et al.​ (2018) 
    ESC Heart Failure, 5(4) pp. 642​-648​.​ DOI: https://doi.org/10.1002/ehf2.12336 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper
    ​ ​Empagliflozin directly improves diastolic function in human heart failure​
    Pabel, S. ; Wagner, S. ; Bollenberg, H.; Bengel, P. ; Kovács, Á.; Schach, C. & Tirilomis, P. et al.​ (2018) 
    European Journal of Heart Failure, 20(12) pp. 1690​-1700​.​ DOI: https://doi.org/10.1002/ejhf.1328 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart​
    Dybkova, N.; Ahmad, S. ; Pabel, S. ; Tirilomis, P.; Hartmann, N. ; Fischer, T. H   & Bengel, P.  et al.​ (2018) 
    Cardiovascular Research, 114(13) pp. 1728​-1737​.​ DOI: https://doi.org/10.1093/cvr/cvy152 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure​
    Fischer, T. H. ; Eiringhaus, J. ; Dybkova, N.; Saadatmand, A.; Pabel, S. ; Weber, S. & Wang, Y. et al.​ (2018) 
    European Journal of Heart Failure, 20(12) pp. 1673​-1685​.​ DOI: https://doi.org/10.1002/ejhf.1297 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology​
    Hartmann, N. H. ; Mason, F. E. ; Braun, I.; Pabel, S. ; Voigt, N. ; Schotola, H. & Fischer, T. H.  et al.​ (2016) 
    Journal of Molecular and Cellular Cardiology, 94 pp. 95​-106​.​ DOI: https://doi.org/10.1016/j.yjmcc.2016.03.012 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes​
    Hartmann, N. H. ; Pabel, S. ; Herting, J. ; Schatter, F. ; Renner, A.; Gummert, J. & Schotola, H. et al.​ (2016) 
    Heart Rhythm, 14(3) pp. 412​-419​.​ DOI: https://doi.org/10.1016/j.hrthm.2016.09.014 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure​
    Fischer, T. H. ; Herting, J. ; Eiringhaus, J. ; Pabel, S. ; Hartmann, N. H. ; Ellenberger, D.   & Friedrich, M.  et al.​ (2016) 
    EP Europace, 18(9) pp. 1440​-1448​.​ DOI: https://doi.org/10.1093/europace/euv313 
    ​Details  DOI  PMID  PMC  WoS 

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