Dr. Lars Tatenhorst

 
Staff Status
unigoe
 

1-14 of 14
 
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  • 2021 Journal Article | Original Work | 
    ​ Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein
    Martinez Hernandez, A. ; Silbern, I.; Geffers, I.; Tatenhorst, L. ; Becker, S. ; Urlaub, H.   & Zweckstetter, M.  et al. (2021) 
    Frontiers in Neuroscience15.​
    Details  DOI 
  • 2021 Journal Article | Original Work | 
    ​ AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo
    Ribas, V. T. ; Vahsen, B. F.; Tatenhorst, L. ; Estrada, V.; Dambeck, V. ; Almeida, R. A. & Bähr, M.  et al. (2021) 
    Cell Death & Disease12(2).​
    Details  DOI 
  • 2020 Journal Article | 
    ​ Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease
    Maass, F. ; Rikker, S.; Dambeck, V. ; Warth, C.; Tatenhorst, L. ; Csoti, I. & Schmitz, M.  et al. (2020) 
    Scientific Reports10(1).​
    Details  DOI 
  • 2020 Journal Article
    ​ Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing
    Vahsen, B. F.; Ribas, V. T. ; Sundermeyer, J.; Boecker, A.; Dambeck, V. ; Lenz, C.   & Shomroni, O.  et al. (2020) 
    Cell Death and Differentiation27(10) pp. 2810-2827.​
    Details  DOI 
  • 2019 Journal Article
    ​ AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease
    Balke, D.; Tatenhorst, L. ; Dambeck, V. ; Ribas, V. T. ; Vahsen, B. F.; Michel, U.   & Bähr, M.  et al. (2019) 
    Molecular Neurobiology57(2) pp. 685-697.​
    Details  DOI 
  • 2018 Journal Article
    ​ ROCK inhibition in models of neurodegeneration and its potential for clinical translation
    Koch, J. C. ; Tatenhorst, L. ; Roser, A.-E. ; Saal, K.-A. ; Tönges, L.   & Lingor, P.  (2018) 
    Pharmacology & Therapeutics189 pp. 1-21.​
    Details  DOI 
  • 2018 Journal Article
    ​ miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons
    Roser, A.-E. ; Caldi Gomes, L.; Halder, R. ; Jain, G.; Maass, F. ; Tönges, L.   & Tatenhorst, L.  et al. (2018) 
    Molecular Therapy - Nucleic Acids11 pp. 9-22.​
    Details  DOI 
  • 2017 Journal Article
    ​ Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation
    Carboni, E. ; Tatenhorst, L. ; Tönges, L. ; Barski, E. ; Dambeck, V. ; Bähr, M.   & Lingor, P.  (2017) 
    NeuroMolecular Medicine19(2-3) pp. 309-321.​
    Details  DOI 
  • 2016 Journal Article | 
    ​ Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease
    Tatenhorst, L. ; Eckermann, K.; Dambeck, V. ; Fonseca-Ornelas, L.; Walle, H.; Lopes Da Fonseca, T. & Koch, J. C.  et al. (2016) 
    Acta Neuropathologica Communication4(1) art. 39.​
    Details  DOI  PMID  PMC 
  • 2015 Journal Article
    ​ AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
    Saal, K.-A. ; Koch, J. C. ; Tatenhorst, L. ; Szegő, É. M. ; Ribas, V. T. ; Michel, U.   & Bähr, M.  et al. (2015) 
    Neurobiology of Disease73 pp. 150-162.​
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons
    Koch, J. C. ; Bitow, F.; Haack, J.; D'Hedouville, Z.; Zhang, J.-N.; Tönges, L.   & Michel, U.  et al. (2015) 
    Cell Death and Disease6 art. e1811.​
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | 
    ​ Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease
    Tönges, L. ; Szegö, E. M. ; Hause, P.; Saal, K.-A. ; Tatenhorst, L. ; Koch, J. C.   & D'Hedouville, Z. et al. (2014) 
    Frontiers in Aging Neuroscience6 art. UNSP 239.​
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article
    ​ Rho Kinase Inhibition by Fasudil in the Striatal 6-Hydroxydopamine Lesion Mouse Model of Parkinson Disease
    Tatenhorst, L. ; Tönges, L. ; Saal, K.-A. ; Koch, J. C. ; Szegő, É. M. ; Bähr, M.   & Lingor, P.  (2014) 
    Journal of Neuropathology and Experimental Neurology73(8) pp. 770-779.​
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | 
    ​ Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease
    Tönges, L. ; Frank, T. ; Tatenhorst, L. ; Saal, K. A. ; Koch, J. C. ; Szego, E. M.   & Bähr, M.  et al. (2012) 
    Brain135(11) pp. 3355-3370.​
    Details  DOI  PMID  PMC  WoS 

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