Dr. Lars Tatenhorst

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unigoe
 

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  • 2021 | Journal Article | Research Paper | 
    ​ ​Ribas, V. T., Vahsen, B. F., Tatenhorst, L., Estrada, V., Dambeck, V., Almeida, R. A., Bähr, M. ... Lingor, P. (2021). ​AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo. Cell Death & Disease, 12(2), . ​doi: https://doi.org/10.1038/s41419-021-03503-3 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Martinez Hernandez, A., Silbern, I., Geffers, I., Tatenhorst, L., Becker, S., Urlaub, H., Zweckstetter, M. ... Eichele, G. (2021). ​Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein. Frontiers in Neuroscience, 15, . ​doi: https://doi.org/10.3389/fnins.2021.643391 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Vahsen, B. F., Ribas, V. T., Sundermeyer, J., Boecker, A., Dambeck, V., Lenz, C., Shomroni, O. ... Lingor, P. (2020). ​Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death and Differentiation, 27(10), ​2810​-2827​. ​doi: https://doi.org/10.1038/s41418-020-0543-y 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Maass, F., Rikker, S., Dambeck, V., Warth, C., Tatenhorst, L., Csoti, I., Schmitz, M. ... Lingor, P. (2020). ​Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease. Scientific Reports, 10(1), . ​doi: https://doi.org/10.1038/s41598-020-65503-1 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Balke, D., Tatenhorst, L., Dambeck, V., Ribas, V. T., Vahsen, B. F., Michel, U., Bähr, M. ... Lingor, P. (2019). ​AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease. Molecular Neurobiology, 57(2), ​685​-697​. ​doi: https://doi.org/10.1007/s12035-019-01744-0 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Roser, Anna-Elisa, Caldi Gomes, L., Halder, R., Jain, G., Maass, F., Tönges, L., Tatenhorst, L. ... Lingor, P. (2018). ​miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons. Molecular Therapy - Nucleic Acids, 11, ​9​-22​. ​doi: https://doi.org/10.1016/j.omtn.2018.01.005 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Koch, J. C., Tatenhorst, L., Roser, Anna-Elisa, Saal, Kim-Ann, Tönges, L. & Lingor, P. (2018). ​ROCK inhibition in models of neurodegeneration and its potential for clinical translation. Pharmacology & Therapeutics, 189, ​1​-21​. ​doi: https://doi.org/10.1016/j.pharmthera.2018.03.008 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Carboni, E., Tatenhorst, L., Tönges, L., Barski, E., Dambeck, V., Bähr, M. & Lingor, P. (2017). ​Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation. NeuroMolecular Medicine, 19(2-3), ​309​-321​. ​doi: https://doi.org/10.1007/s12017-017-8447-9 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Tatenhorst, L., Eckermann, K., Dambeck, V., Fonseca-Ornelas, L., Walle, H., Lopes Da Fonseca, T., Koch, J. C. ... Lingor, P. (2016). ​Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease. Acta Neuropathologica Communication, 4(1), Article 39​. ​doi: https://doi.org/10.1186/s40478-016-0310-y 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Koch, J. C., Bitow, F., Haack, J., D'Hedouville, Z., Zhang, J-N, Tönges, L., Michel, U. ... Lingor, P. (2015). ​Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons. Cell Death and Disease, 6, Article e1811​. ​doi: https://doi.org/10.1038/cddis.2015.169 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Saal, K.-A., Koch, J. C., Tatenhorst, L., Szegő, É. M., Ribas, V. T., Michel, U., Bähr, M. ... Lingor, P. (2015). ​AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo. Neurobiology of Disease, 73, ​150​-162​. ​doi: https://doi.org/10.1016/j.nbd.2014.09.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Tönges, L., Szegö, E. M., Hause, P., Saal, K.-A., Tatenhorst, L., Koch, J. C., D'Hedouville, Z. ... Lingor, P. (2014). ​Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease. Frontiers in Aging Neuroscience, 6, Article UNSP 239​. ​doi: https://doi.org/10.3389/fnagi.2014.00239 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Tatenhorst, L., Tönges, L., Saal, Kim-Ann, Koch, J. C., Szegő, É. M., Bähr, M. & Lingor, P. (2014). ​Rho Kinase Inhibition by Fasudil in the Striatal 6-Hydroxydopamine Lesion Mouse Model of Parkinson Disease. Journal of Neuropathology and Experimental Neurology, 73(8), ​770​-779​. ​doi: https://doi.org/10.1097/nen.0000000000000095 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | Research Paper | 
    ​ ​Tönges, L., Frank, T., Tatenhorst, L., Saal, K. A., Koch, J. C., Szego, E. M., Bähr, M. ... Lingor, P. (2012). ​Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease. Brain, 135(11), ​3355​-3370​. ​doi: https://doi.org/10.1093/brain/aws254 
    ​Details  DOI  PMID  PMC  WoS 

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