Dr. Wiebke Möbius

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  • 2023 Journal Article
    ​ ​Neodymium acetate as a contrast agent for x-ray phase-contrast tomography​
    Reichmann, J. ; Ruhwedel, T.; Möbius, W.   & Salditt, T. ​ (2023) 
    Journal of Medical Imaging10(5) art. 056001​.​ DOI: https://doi.org/10.1117/1.JMI.10.5.056001 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​White matter integrity in mice requires continuous myelin synthesis at the inner tongue​
    Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K. ; Jahn, O. ; Piepkorn, L. & Agüi-Gonzalez, P.  et al.​ (2022) 
    Nature Communications13(1) art. 1163​.​ DOI: https://doi.org/10.1038/s41467-022-28720-y 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography​
    Eckermann, M.; van der Meer, F.; Cloetens, P.; Ruhwedel, T.; Möbius, W. ; Stadelmann, C.   & Salditt, T. ​ (2021) 
    Biomedical Optics Express12(12) pp. 7582​.​ DOI: https://doi.org/10.1364/BOE.434885 
    Details  DOI 
  • 2021 Preprint
    ​ ​Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development​
    Djannatian, M.; Weikert, U.; Safaiyan, S.; Wrede, C.; Deichsel, C.; Kislinger, G.& Ruhwedel, T. et al.​ (2021). DOI: https://doi.org/10.1101/2021.02.02.429485 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​New Species Can Broaden Myelin Research: Suitability of Little Skate, Leucoraja erinacea​
    Möbius, W. ; Hümmert, S.; Ruhwedel, T.; Kuzirian, A. & Gould, R.​ (2021) 
    Life11(2) pp. 136​.​ DOI: https://doi.org/10.3390/life11020136 
    Details  DOI  PMID  PMC 
  • 2020 Preprint
    ​ ​White matter integrity requires continuous myelin synthesis at the inner tongue​
    Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K.; Jahn, O.; Piepkorn, L.& Agüi-Gonzalez, P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.09.02.279612 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity​
    Vaes, J. E. G.; Kammen, C. M.; Trayford, C.; Toorn, A.; Ruhwedel, T.; Benders, M. J. N. L. & Dijkhuizen, R. M. et al.​ (2020) 
    Glia69(3) pp. 655​-680​.​ DOI: https://doi.org/10.1002/glia.23919 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​A role of oligodendrocytes in information processing​
    Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A. ; Tzvetanova, I. D.; Battefeld, A. & Kusch, K.  et al.​ (2020) 
    Nature Communications11(1).​ DOI: https://doi.org/10.1038/s41467-020-19152-7 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis​
    Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L. ; Schlaphoff, L.; Depp, C. & Düking, T. et al.​ (2020) 
    Nature Neuroscience24(1) pp. 47​-60​.​ DOI: https://doi.org/10.1038/s41593-020-00757-6 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy​
    Steyer, A. M.; Ruhwedel, T.; Nardis, C.; Werner, H. B. ; Nave, K.-A.   & Möbius, W. ​ (2020) 
    Journal of Structural Biology210(2) art. S1047847720300587​.​ DOI: https://doi.org/10.1016/j.jsb.2020.107492 
    Details  DOI  PMID  PMC 
  • 2019 Conference Paper
    ​ ​Evaluation of different heavy-metal stains and embedding media for phase contrast tomography of neuronal tissue​
    Eckermann, M.; Töpperwien, M. ; Ruhwedel, T.; Möbius, W.   & Salditt, T. ​ (2019)
    In:Müller-Myhsok, Bertram; Wang, Geng​ (Eds.), ​Proc. SPIE 11113 p. 21. (Vol. 12). , San Diego, California, United States. DOI: https://doi.org/10.1117/12.2528432 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Biological Sample Preparation by High-pressure Freezing, Microwave-assisted Contrast Enhancement, and Minimal Resin Embedding for Volume Imaging​
    Steyer, A. M.; Ruhwedel, T. & Möbius, W. ​ (2019) 
    Journal of Visualized Experiments,(145).​ DOI: https://doi.org/10.3791/59156 
    Details  DOI 
  • 2019 Journal Article | Erratum | 
    ​ ​Correction to: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease​
    Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A.; Spieth, L.; Düking, T.; Schneider, L. V. & Schlaphoff, L. et al.​ (2019) 
    Acta Neuropathologica138(4) pp. 673​-674​.​ DOI: https://doi.org/10.1007/s00401-019-02064-2 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease​
    Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A. ; Spieth, L.; Düking, T.; Schneider, L. V. & Schlaphoff, L. et al.​ (2019) 
    Acta Neuropathologica138(1) pp. 147​-161​.​ DOI: https://doi.org/10.1007/s00401-019-01985-2 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia​
    Weil, M.-T.; Heibeck, S.; Töpperwien, M. ; tom Dieck, S.; Ruhwedel, T.; Salditt, T.   & Rodicio, M. C. et al.​ (2018) 
    The Journal of Neuroscience38(29) pp. 6586​-6596​.​ DOI: https://doi.org/10.1523/JNEUROSCI.1034-18.2018 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​Defective cholesterol clearance limits remyelination in the aged central nervous system​
    Cantuti-Castelvetri, L.; Fitzner, D.; Bosch-Queralt, M.; Weil, M.-T.; Su, M.; Sen, P. & Ruhwedel, T. et al.​ (2018) 
    Science359(6376) pp. 684​-688​.​ DOI: https://doi.org/10.1126/science.aan4183 
    Details  DOI 
  • 2017 Journal Article | Research Paper | 
    ​ ​Phase-contrast tomography of sciatic nerves: image quality and experimental parameters​
    Töpperwien, M. ; Krenkel, M.; Ruhwedel, T.; Möbius, W. ; Pacureanu, A.; Cloetens, P. & Salditt, T. ​ (2017) 
    Journal of Physics. Conference Series849 art. 012001​.​ DOI: https://doi.org/10.1088/1742-6596/849/1/012001 
    Details  DOI 
  • 2017 Conference Abstract
    ​ ​Temporal sound processing in the auditory cortex is influenced by changes in myelin integrity​
    Moore, S.; Möbius, W. ; Ruhwedel, T.; Weil, M.-T.; Nave, K.-A. & de Hoz, L.​ (2017)
    Glia65 pp. E396​-E397. ​13th European Meeting on Glial Cells in Health and Disease​, Edinburgh, SCOTLAND.
    Hoboken​: Wiley.
    Details  WoS 
  • 2017 Journal Article | 
    ​ ​Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model​
    Berghoff, S. A.; Düking, T.; Spieth, L.; Winchenbach, J.; Stumpf, S. K.; Gerndt, N. & Kusch, K. et al.​ (2017) 
    Acta Neuropathologica Communications5(1).​ DOI: https://doi.org/10.1186/s40478-017-0497-6 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Dietary cholesterol promotes repair of demyelinated lesions in the adult brain​
    Berghoff, S. A.; Gerndt, N.; Winchenbach, J.; Stumpf, S. K.; Hosang, L.; Odoardi, F.   & Ruhwedel, T. et al.​ (2017) 
    Nature Communications8 art. 14241​.​ DOI: https://doi.org/10.1038/ncomms14241 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​Cortical network dysfunction caused by a subtle defect of myelination​
    Poggi, G.; Boretius, S. ; Möbius, W. ; Moschny, N.; Baudewig, J. ; Ruhwedel, T. & Hassouna, I.  et al.​ (2016) 
    Glia64(11) pp. 2025​-2040​.​ DOI: https://doi.org/10.1002/glia.23039 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases​
    Weil, M.-T.; Möbius, W. ; Winkler, A.; Ruhwedel, T.; Wrzos, C.; Romanelli, E. & Bennett, J. L. et al.​ (2016) 
    Cell Reports16(2) pp. 314​-322​.​ DOI: https://doi.org/10.1016/j.celrep.2016.06.008 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Conference Abstract
    ​ ​Molecular mechanism of myelin disassembly​
    Weil, M.-T.; Möbius, W. ; Ruhwedel, T.; Frey, S.; Kursula, P.; Winkler, A. & Stadelmann-Nessler, C.  et al.​ (2015)
    Glia63 , Bilbao, SPAIN.
    Hoboken​: Wiley-blackwell.
    Details  WoS 
  • 2014 Journal Article | 
    ​ ​Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice.​
    Gritsch, S.; Lu, J.; Thilemann, S.; Wörtge, S.; Möbius, W. ; Bruttger, J. & Karram, K. et al.​ (2014) 
    Nature communications5 art. 5472​.​ DOI: https://doi.org/10.1038/ncomms6472 
    Details  DOI  PMID  PMC 
  • 2013 Journal Article
    ​ ​Cryo FIB-SEM: Volume imaging of cellular ultrastructure in native frozen specimens​
    Schertel, A.; Snaidero, N.; Han, H.-M.; Ruhwedel, T.; Laue, M.; Grabenbauer, M. & Möbius, W. ​ (2013) 
    Journal of Structural Biology184(2) pp. 355​-360​.​ DOI: https://doi.org/10.1016/j.jsb.2013.09.024 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet​
    Saher, G.; Rudolphi, F.; Corthals, K.; Ruhwedel, T.; Schmidt, K.-F.; Loewel, S. & Dibaj, P. et al.​ (2012) 
    Nature Medicine18(7) pp. 1130​-+​.​ DOI: https://doi.org/10.1038/nm.2833 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Aspartoacylase-LacZ Knockin Mice: An Engineered Model of Canavan Disease​
    Mersmann, N.; Tkachev, D.; Jelinek, R.; Röth, P. T.; Möbius, W. ; Ruhwedel, T. & Rühle, S. et al.​ (2011) 
    PLoS ONE6(5) pp. e20336​.​ DOI: https://doi.org/10.1371/journal.pone.0020336 
    Details  DOI 
  • 2010 Book Chapter
    ​ ​Electron Microscopy of the Mouse Central Nervous System​
    Möbius, W. ; Cooper, B.; Kaufmann, W. A.; Imig, C.; Ruhwedel, T.; Snaidero, N.& Saab, A. S. et al.​ (2010)
    In: Electron Microscopy of Model Systems pp. 475​-512. ​Elsevier. DOI: https://doi.org/10.1016/S0091-679X(10)96020-2 
    Details  DOI 

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