Dr. Wiebke Möbius

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  • 2021 | Preprint
    ​ ​Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development​
    Djannatian, M.; Weikert, U.; Safaiyan, S.; Wrede, C.; Deichsel, C.; Kislinger, G.& Ruhwedel, T. et al.​ (2021). DOI: https://doi.org/10.1101/2021.02.02.429485 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis​
    Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L. ; Schlaphoff, L.; Depp, C. & Düking, T. et al.​ (2020) 
    Nature Neuroscience, 24(1) pp. 47​-60​.​ DOI: https://doi.org/10.1038/s41593-020-00757-6 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS​
    Djannatian, M.; Timmler, S.; Arends, M.; Luckner, M.; Weil, M.-T.; Alexopoulos, I. & Snaidero, N. et al.​ (2019) 
    Nature Communications, 10(1).​ DOI: https://doi.org/10.1038/s41467-019-12789-z 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Defective cholesterol clearance limits remyelination in the aged central nervous system​
    Cantuti-Castelvetri, L.; Fitzner, D.; Bosch-Queralt, M.; Weil, M.-T.; Su, M.; Sen, P. & Ruhwedel, T. et al.​ (2018) 
    Science, 359(6376) pp. 684​-688​.​ DOI: https://doi.org/10.1126/science.aan4183 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin​
    Snaidero, N.; Velte, C.; Myllykoski, M.; Raasakka, A.; Ignatev, A.; Werner, H. B. & Erwig, M. S. et al.​ (2017) 
    Cell Reports, 18(2) pp. 314​-323​.​ DOI: https://doi.org/10.1016/j.celrep.2016.12.053 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | 
    ​ ​Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases​
    Weil, M.-T.; Möbius, W. ; Winkler, A.; Ruhwedel, T.; Wrzos, C.; Romanelli, E. & Bennett, J. L. et al.​ (2016) 
    Cell Reports, 16(2) pp. 314​-322​.​ DOI: https://doi.org/10.1016/j.celrep.2016.06.008 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Conference Abstract
    ​ ​Molecular mechanism of myelin disassembly​
    Weil, M.-T.; Möbius, W. ; Ruhwedel, T.; Frey, S.; Kursula, P.; Winkler, A. & Stadelmann-Nessler, C.  et al.​ (2015)
    Glia, 63 , Bilbao, SPAIN.
    Hoboken​: Wiley-blackwell.
    ​Details  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation​
    Kunadt, M.; Eckermann, K.; Stuendl, A.; Gong, J.; Russo, B.; Strauss, K. & Rai, S. et al.​ (2015) 
    Acta Neuropathologica, 129(5) pp. 695​-713​.​ DOI: https://doi.org/10.1007/s00401-015-1408-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Myelin Membrane Wrapping of CNS Axons by PI(3,4,5) P3-Dependent Polarized Growth at the Inner Tongue​
    Snaidero, N.; Möbius, W. ; Czopka, T.; Hekking, L. H. P.; Mathisen, C.; Verkleij, D. & Goebbels, S. et al.​ (2014) 
    Cell, 156(1-2) pp. 277​-290​.​ DOI: https://doi.org/10.1016/j.cell.2013.11.044 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system​
    Bakhti, M.; Snaidero, N.; Schneider, D.; Aggarwal, S.; Möbius, W. ; Janshoff, A.   & Eckhardt, M. et al.​ (2013) 
    Proceedings of the National Academy of Sciences of the United States of America, 110(8) pp. 3143​-3148​.​ DOI: https://doi.org/10.1073/pnas.1220104110 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication​
    Fruehbeis, C.; Froehlich, D.; Kuo, W. P.; Amphornrat, J.; Thilemann, S.; Saab, A. S. & Kirchhoff, F. et al.​ (2013) 
    PLoS Biology, 11(7) art. e1001604​.​ DOI: https://doi.org/10.1371/journal.pbio.1001604 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease​
    Strauss, K.; Goebel, C.; Runz, H.; Möbius, W. ; Weiss, S.; Feussner, I.   & Simons, M. et al.​ (2010) 
    Journal of Biological Chemistry, 285(34) pp. 26279​-26288​.​ DOI: https://doi.org/10.1074/jbc.M110.134775 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C​
    Hsu, C.; Morohashi, Y.; Yoshimura, S.-i.; Manrique-Hoyos, N.; Jung, S.; Lauterbach, M. A. & Bakhti, M. et al.​ (2010) 
    The Journal of Cell Biology, 189(2) pp. 223​-232​.​ DOI: https://doi.org/10.1083/jcb.200911018 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | Research Paper
    ​ ​Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin​
    Fitzner, D.; Schneider, A. ; Kippert, A.; Möbius, W. ; Willig, K. I. ; Hell, S.   & Bunt, G. et al.​ (2006) 
    EMBO Journal, 25(21) pp. 5037​-5048​.​ DOI: https://doi.org/10.1038/sj.emboj.7601376 
    ​Details  DOI  PMID  PMC  WoS 

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