Dr. Wiebke Möbius

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43​
    Heo, D.; Ling, J. P.; Molina-Castro, G. C.; Langseth, A. J.; Waisman, A.; Nave, K.-A.   & Möbius, W.  et al.​ (2022) 
    eLife, 11.​ DOI: https://doi.org/10.7554/eLife.75230 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin​
    Edgar, J. M.; McGowan, E.; Chapple, K. J.; Möbius, W. ; Lemgruber, L.; Insall, R. H. & Nave, K.-A.  et al.​ (2021) 
    Journal of Anatomy, 239(6) pp. 1241​-1255​.​ DOI: https://doi.org/10.1111/joa.13577 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves​
    Eichel, M. A.; Gargareta, V.-I.; D’Este, E. ; Fledrich, R. ; Kungl, T.; Buscham, T. J. & Lüders, K. A. et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-020-18172-7 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​A role of oligodendrocytes in information processing​
    Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A. ; Tzvetanova, I. D.; Battefeld, A. & Kusch, K.  et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-020-19152-7 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia​
    Trevisiol, A. ; Kusch, K. ; Steyer, A. M.; Gregor, I. ; Nardis, C.; Winkler, U. & Köhler, S. et al.​ (2020) 
    PLoS Biology, 18(11) pp. e3000943​.​ DOI: https://doi.org/10.1371/journal.pbio.3000943 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis​
    Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L. ; Schlaphoff, L.; Depp, C. & Düking, T. et al.​ (2020) 
    Nature Neuroscience, 24(1) pp. 47​-60​.​ DOI: https://doi.org/10.1038/s41593-020-00757-6 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy​
    Steyer, A. M.; Ruhwedel, T.; Nardis, C.; Werner, H. B. ; Nave, K.-A.   & Möbius, W. ​ (2020) 
    Journal of Structural Biology, 210(2) art. S1047847720300587​.​ DOI: https://doi.org/10.1016/j.jsb.2020.107492 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease​
    Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A. ; Spieth, L.; Düking, T.; Schneider, L. V. & Schlaphoff, L. et al.​ (2019) 
    Acta Neuropathologica, 138(1) pp. 147​-161​.​ DOI: https://doi.org/10.1007/s00401-019-01985-2 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin​
    Erwig, M. S.; Patzig, J. ; Steyer, A. M.; Dibaj, P. ; Heilmann, M.; Heilmann, I.   & Jung, R. B. et al.​ (2019) 
    eLife, 8.​ DOI: https://doi.org/10.7554/eLife.43888 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia​
    Weil, M.-T.; Heibeck, S.; Töpperwien, M. ; tom Dieck, S.; Ruhwedel, T.; Salditt, T.   & Rodicio, M. C. et al.​ (2018) 
    The Journal of Neuroscience, 38(29) pp. 6586​-6596​.​ DOI: https://doi.org/10.1523/JNEUROSCI.1034-18.2018 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy​
    Fledrich, R. ; Abdelaal, T.; Rasch, L.; Bansal, V.; Schütza, V.; Brügger, B. & Lüchtenborg, C. et al.​ (2018) 
    Nature Communications, 9(1).​ DOI: https://doi.org/10.1038/s41467-018-05420-0 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity​
    Schirmer, L.; Möbius, W. ; Zhao, C.; Cruz-Herranz, A.; Ben Haim, L.; Cordano, C. & Shiow, L. R. et al.​ (2018) 
    eLife, 7.​ DOI: https://doi.org/10.7554/eLife.36428 
    ​Details  DOI  PMID  PMC 
  • 2017 | Conference Abstract
    ​ ​SIRT2 as a genetic modifier of axonal degeneration in white matter tracts​
    Kusch, K. ; Uecker, M. ; Liepold, T. ; Möbius, W. ; Werner, H. B. ; Valerius, O.   & Jahn, O.  et al.​ (2017)
    Glia, 65 ​13th European Meeting on Glial Cells in Health and Disease​, Edinburgh, Scotland.
    Hoboken​: Wiley.
    ​Details  WoS 
  • 2016 | Journal Article | 
    ​ ​Cortical network dysfunction caused by a subtle defect of myelination​
    Poggi, G.; Boretius, S. ; Möbius, W. ; Moschny, N.; Baudewig, J. ; Ruhwedel, T. & Hassouna, I.  et al.​ (2016) 
    Glia, 64(11) pp. 2025​-2040​.​ DOI: https://doi.org/10.1002/glia.23039 
    ​Details  DOI 
  • 2016 | Journal Article | Research Paper
    ​ ​Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism​
    Saab, A. S. ; Tzvetavona, I. D. ; Trevisiol, A. ; Baltan, S.; Dibaj, P. ; Kusch, K.   & Möbius, W.  et al.​ (2016) 
    Neuron, 91(1) pp. 119​-132​.​ DOI: https://doi.org/10.1016/j.neuron.2016.05.016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system​
    Werner, H. B. ; Kraemer-Albers, E.-M.; Strenzke, N. ; Saher, G.; Tenzer, S.; Ohno-Iwashita, Y. & Monasterio-Schrader, P. de  et al.​ (2013) 
    Glia, 61(4) pp. 567​-586​.​ DOI: https://doi.org/10.1002/glia.22456 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity​
    Fünfschilling, U.; Supplie, L. M.; Mahad, D.; Boretius, S. ; Saab, A. S. ; Edgar, J. & Brinkmann, B. G. et al.​ (2012) 
    Nature, 485(7397) pp. 517​-521​.​ DOI: https://doi.org/10.1038/nature11007 
    ​Details  DOI 
  • 2007 | Journal Article
    ​ ​Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy​
    Meyer zu Hörste, G.; Prukop, T. ; Liebetanz, D. ; Möbius, W. ; Nave, K.-A.   & Sereda, M. W. ​ (2007) 
    Annals of Neurology, 61(1) pp. 61​-72​.​ DOI: https://doi.org/10.1002/ana.21026 
    ​Details  DOI  WoS 

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