Dr. rer. nat. Ellen Gerhardt

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  • 2022 Journal Article
    ​ ​Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity​
    Brás, I. C.; Khani, M. H. ; Vasili, E.; Möbius, W. ; Riedel, D. ; Parfentev, I. & Gerhardt, E.  et al.​ (2022) 
    Journal of Parkinson's Disease, pp. 1​-26​.​ DOI: https://doi.org/10.3233/JPD-223516 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | Research Paper | 
    ​ ​Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation​
    Torres-Garcia, L.; P. Domingues, J. M.; Brandi, E.; Haikal, C.; Mudannayake, J. M.; Brás, I. C. & Gerhardt, E.  et al.​ (2022) 
    Scientific Reports12(1) art. 2987​.​ DOI: https://doi.org/10.1038/s41598-022-06846-9 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | Research Paper
    ​ ​Ectosomes and exosomes modulate neuronal spontaneous activity​
    Brás, I. C.; Khani, M. H. ; Riedel, D. ; Parfentev, I.; Gerhardt, E. ; van Riesen, C. & Urlaub, H.  et al.​ (2022) 
    Journal of Proteomics269 art. 104721​.​ DOI: https://doi.org/10.1016/j.jprot.2022.104721 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Overview | 
    ​ ​Synucleinopathies: Where we are and where we need to go​
    Brás, I. C.; Dominguez‐Meijide, A.; Gerhardt, E. ; Koss, D.; Lázaro, D. F. ; Santos, P. I. & Vasili, E. et al.​ (2020) 
    Journal of Neurochemistry153(4) pp. 433​-454​.​ DOI: https://doi.org/10.1111/jnc.14965 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article
    ​ ​Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1​
    Brasil, A. de A.; de Carvalho, M. D. C.; Gerhardt, E. ; Queiroz, D. D.; Pereira, M. D.; Outeiro, T. F.   & Eleutherio, E. C. A.​ (2019) 
    Proceedings of the National Academy of Sciences of the United States of America116(51) pp. 25991​-26000​.​ DOI: https://doi.org/10.1073/pnas.1902483116 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Overview
    ​ ​LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?​
    Outeiro, T. F. ; Harvey, K.; Dominguez-Meijide, A. & Gerhardt, E. ​ (2019) 
    Biochemical Society Transactions47(3) pp. 827​-838​.​ DOI: https://doi.org/10.1042/BST20180466 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​Tau deletion promotes brain insulin resistance​
    Marciniak, E.; Leboucher, A.; Caron, E.; Ahmed, T.; Tailleux, A.; Dumont, J. & Issad, T. et al.​ (2017) 
    Journal of Experimental Medicine214(8) pp. 2257​-2269​.​ DOI: https://doi.org/10.1084/jem.20161731 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage​
    Paiva, I. ; Pinho, R. ; Pavlou, M. A. ; Hennion, M. ; Wales, P. ; Schütz, A.-L.   & Rajput, A.  et al.​ (2017) 
    Human Molecular Genetics26(12) pp. 2231​-2246​.​ DOI: https://doi.org/10.1093/hmg/ddx114 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Implications of fALS Mutations on Sod1 Function and Oligomerization in Cell Models​
    Brasil, A. A.; Magalhães, R. S. S.; De Carvalho, M. D. C.; Paiva, I. ; Gerhardt, E. ; Pereira, M. D. & Outeiro, T. F.  et al.​ (2017) 
    Molecular Neurobiology55(6) pp. 5269​-5281​.​ DOI: https://doi.org/10.1007/s12035-017-0755-4 
    Details  DOI 
  • 2016 Journal Article
    ​ ​Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity​
    Tenreiro, S.; Rosado-Ramos, R.; Gerhardt, E. ; Favretto, F. ; Magalhães, F.; Popova, B.   & Becker, S.  et al.​ (2016) 
    Human Molecular Genetics25(2) pp. 275​-290​.​ DOI: https://doi.org/10.1093/hmg/ddv470 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​LRRK2 Promotes Tau Accumulation, Aggregation and Release​
    Guerreiro, P. S. ; Gerhardt, E. ; Da Fonseca, T. L.; Bähr, M. ; Outeiro, T. F.   & Eckermann, K.​ (2016) 
    Molecular Neurobiology53(5) pp. 3124​-3135​.​ DOI: https://doi.org/10.1007/s12035-015-9209-z 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation​
    Lazaro, D. F. ; Rodrigues, E. F. ; Langohr, R.; Shahpasandzadeh, H.; Ribeiro, T.; Guerreiro, P.   & Gerhardt, E.  et al.​ (2014) 
    PLoS Genetics10 art. e1004741​.​ DOI: https://doi.org/10.1371/journal.pgen.1004741 
    Details  DOI  PMID  PMC  WoS 
  • 2002 Journal Article | Research Paper
    ​ ​Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis​
    Straten, G.; Schmeer, C.; Kretz, A.; Gerhardt, E. ; Kugler, S. ; Schulz, J. B.   & Gravel, C. et al.​ (2002) 
    Neurobiology of Disease11(1) pp. 123​-133​.​ DOI: https://doi.org/10.1006/nbdi.2002.0543 
    Details  DOI  PMID  PMC  WoS 
  • 2001 Journal Article | Research Paper
    ​ ​Neuron-specific expression of therapeutic proteins: Evaluation of different cellular promoters in recombinant adenoviral vectors​
    Kügler, S. ; Meyn, L.; Holzmüller, H.; Gerhardt, E. ; Isenmann, S.; Schulz, J. B.   & Bähr, M. ​ (2001) 
    Molecular and Cellular Neuroscience17(1) pp. 78​-96​.​ DOI: https://doi.org/10.1006/mcne.2000.0929 
    Details  DOI  PMID  PMC  WoS 
  • 2001 Journal Article | Research Paper
    ​ ​Cascade of caspase activation in potassium-deprived cerebellar granule neurons: Targets for treatment with peptide and protein inhibitors of apoptosis​
    Gerhardt, E. ; Kugler, S. ; Leist, M.; Beier, C.; Berliocchi, L.; Volbracht, C. & Weller, M. et al.​ (2001) 
    Molecular and Cellular Neuroscience17(4) pp. 717​-731​.​ DOI: https://doi.org/10.1006/mcne.2001.0962 
    Details  DOI  PMID  PMC  WoS 
  • 2000 Journal Article | Research Paper
    ​ ​Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease​
    Eberhardt, O.; Coelln, R. V.; Kugler, S. ; Lindenau, J.; Rathke-Hartlieb, S.; Gerhardt, E.   & Haid, S. et al.​ (2000) 
    The Journal of Neuroscience20(24) pp. 9126​-9134​.​ DOI: https://doi.org/10.1523/JNEUROSCI.20-24-09126.2000 
    Details  DOI  PMID  PMC  WoS 

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