Prof. Dr. Elisabeth Zeisberg

 
Staff Status
unigoe
 

1-55 of 55
 
The bibliographical data in your publication list are complete
You can correct existing data in the blue highlighted fields.To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
The bibliographic data in your publication list may be incomplete. You can
  • add any missing data in the fields marked in red or
  • correct existing data in the blue highlighted fields.
To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
Check/Uncheck all
  • 2023 Journal Article | 
    ​ ​Kanwischer L, Xu X, Saifuddin AB, Maamari S, Tan X, Alnour F, et al. ​Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis​. ​​Clinical Epigenetics. ​2023;​15​(1). ​doi:10.1186/s13148-023-01561-2. 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article | 
    ​ ​Hulshoff MS, Schellinger IN, Xu X, Fledderus J, Rath SK, Wong FC, et al. ​miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus​. ​​Diabetology & Metabolic Syndrome. ​2023;​15​(1). ​doi:10.1186/s13098-022-00966-y. 
    Details  DOI 
  • 2021 Book Chapter
    ​ ​Xu X, Zeisberg EM. ​High-Fidelity CRISPR/Cas9-Based Gene-Specific​. ​In: Bogdanovic O, Vermeulen M​, editors. ​Methods in Molecular Biology TET Proteins and DNA Demethylation : Methods and Protocols. ​New York, NY: ​Springer US; ​2021. p. 195​-206​. ​(Methods in Molecular Biology; vol. 2272). doi:10.1007/978-1-0716-1294-1_11. 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, et al. ​Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis​. ​​Science Signaling. ​2020;​13​(635). ​doi:10.1126/scisignal.aaz2597. 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Puls M, Beuthner BE, Topci R, Vogelgesang A, Bleckmann A, Sitte M, et al. ​Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis​. ​​European Heart Journal. ​2020;​41​(20):​​1903​-1914​. ​doi:10.1093/eurheartj/ehaa033. 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Xu X, Hulshoff MS, Tan X, Zeisberg M, Zeisberg EM. ​CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications​. ​​International Journal of Molecular Sciences. ​2020;​21​(9):​​3038​. ​doi:10.3390/ijms21093038. 
    Details  DOI  PMID  PMC 
  • 2020 Preprint
    ​ ​Michurina A, Sakib S, Kerimoglu C, Krüger DM, Kaurani L, Islam R, et al. ​SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​. ​​2020. Available from: https://doi.org/10.1101/2020.08.07.240853​
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​Beuthner BEC, Topci R, Derks M, Franke T, Seelke S, Puls M, et al. ​Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement​. ​​Open Journal of Bioresources. ​2020;​7​. ​doi:10.5334/ojb.65. 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Wilhelmi T, Xu X, Tan X, Hulshoff MS, Maamari S, Sossalla S, et al. ​Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1​. ​​Theranostics. ​2020;​10​(9):​​3905​-3924​. ​doi:10.7150/thno.38640. 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Backhaus SJ, Lange T, Beuthner BE, Topci R, Wang X, Kowallick JT, et al. ​Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis​. ​​Journal of Cardiovascular Magnetic Resonance. ​2020;​22​(1):​​46​. ​doi:10.1186/s12968-020-00632-0. 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Liu Q, Zhu, Lang-Jing, Waaga-Gasser AM, Ding Y, Cao M, Jadhav SJ, et al. ​The axis of local cardiac endogenous Klotho-TGF-β1-Wnt signaling mediates cardiac fibrosis in human​. ​​Journal of Molecular and Cellular Cardiology. ​2019;​136​:​​113​-124​. ​doi:10.1016/j.yjmcc.2019.09.004. 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Dere E, Ronnenberg A, Tampe B, Arinrad S, Schmidt M, Zeisberg E, et al. ​Cognitive, emotional and social phenotyping of mice in an observer-independent setting​. ​​Neurobiology of Learning and Memory. ​2018;​150​:​​136​-150​. ​doi:10.1016/j.nlm.2018.02.023. 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Hulshoff MS, Xu X, Krenning G, Zeisberg EM. ​Epigenetic Regulation of Endothelial-to-Mesenchymal Transition in Chronic Heart Disease​. ​​Arteriosclerosis, Thrombosis, and Vascular Biology. ​2018;​38​(9):​​1986​-1996​. ​doi:10.1161/ATVBAHA.118.311276. 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Helmke A, Casper J, Nordlohne J, David S, Haller H, Zeisberg EM, et al. ​Endothelial‐to‐mesenchymal transition shapes the atherosclerotic plaque and modulates macrophage function​. ​​The FASEB Journal. ​2018;​33​(2):​​2278​-2289​. ​doi:10.1096/fj.201801238R. 
    Details  DOI 
  • 2018 Journal Article | Research Paper | 
    ​ ​Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff MS, Saito S, et al. ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​. ​​Nature Communications. ​2018;​9​(1):​​1​-15​. ​doi:10.1038/s41467-018-05766-5. 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Hulshoff MS, Rath SK, Xu X, Zeisberg M, Zeisberg EM. ​Causal Connections From Chronic Kidney Disease to Cardiac Fibrosis​. ​​Seminars in nephrology. ​2018;​38​(6):​​629​-636​. ​doi:10.1016/j.semnephrol.2018.08.007. 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, et al. ​Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​. ​​Science Translational Medicine. ​2018;​10​(458). ​doi:10.1126/scitranslmed.aan0724. 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​Tampe B, Tampe D, Nyamsuren G, Klöpper F, Rapp G, Kauffels A, et al. ​Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure​. ​​The Journal of Clinical Investigation. ​2018;​128​(7):​​3053​-3070​. ​doi:10.1172/JCI89632. 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Tampe B, Steinle U, Tampe D, Carstens JL, Korsten P, Zeisberg EM, et al. ​Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression​. ​​Kidney International. ​2017;​91​(1):​​157​-176​. ​doi:10.1016/j.kint.2016.07.042. 
    Details  DOI  PMID  PMC 
  • 2016 Conference Abstract
    ​ ​Zuo H, Poppinga WJ, Zeisberg EM, Nikolaev VO, Schmidt M. ​Monitoring Local Pulmonary Camp Levels: Combining Precision Cut Lung Slice (pcls) And Fluorescence Resonance Energy Transfer (fret) Technologies In Mice​. ​ International Conference of the American-Thoracic-Society (ATS); ​San Francisco, CA. ​American Journal of Respiratory and Critical Care Medicine. ​2016;​193​
    Details  WoS 
  • 2016 Conference Abstract
    ​ ​Alnour F, Xu X, Zeisberg M, Zeisberg EM. ​KIAA0182: a new gene relevant for cardiac development​. ​​Der Internist. ​2016;​57​:S18​-S19​. ​
    Details  WoS 
  • 2016 Conference Abstract
    ​ ​Tan X, Xu X, Zeisberg EM, Zeisberg M. ​High Phosphate Induces Endothelial-Mesenchymal Transition of Human Coronary Endothelial Cells by Epigenetic Regulation of DNMT1: a Link from Chronic Kidney to Cardiovascular Disease​. ​​Der Internist. ​2016;​57​
    Details  WoS 
  • 2016 Conference Abstract
    ​ ​Xu X, Tan X, Zeisberg M, Zeisberg E. ​Hypoxia induced endothelial to mesenchymal transition is associated with promoter hypermethylation in human RASAL1 coronary endothelial cells.​. ​​Der Internist. ​2016;​57​:S20​-S21​. ​
    Details  WoS 
  • 2016 Journal Article | 
    ​ ​Patschan SA, Tampe D, Mueller C, Seitz C, Herink C, Mueller GA, et al. ​Early Endothelial Progenitor Cells (eEPCs) in systemic sclerosis (SSc) - dynamics of cellular regeneration and mesenchymal transdifferentiation​. ​​BMC Musculoskeletal Disorders. ​2016;​17​. ​doi:10.1186/s12891-016-1197-2. 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper | 
    ​ ​Tan X, Xu X, Zeisberg M, Zeisberg EM. ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​. ​​PLoS ONE. ​2016;​11​(1):​​1​-17​. ​doi:10.1371/journal.pone.0147816. 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper
    ​ ​Tan X, Xu X, Zeisberg EM, Zeisberg M. ​High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​. ​​Biochemical and Biophysical Research Communications. ​2016;​472​(3):​​459​-464​. ​doi:10.1016/j.bbrc.2016.01.077. 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper
    ​ ​Liu X, Qi J, Xu X, Zeisberg M, Guan-Schmidt K, Zeisberg EM. ​Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective method​. ​​Differentiation. ​2016;​92​(4):​​225​-236​. ​doi:10.1016/j.diff.2016.05.004. 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Xu X, Tan X, Hulshoff MS, Wilhelmi T, Zeisberg M, Zeisberg EM. ​Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells​. ​​FEBS Letters. ​2016;​590​(8):​​1222​-1233​. ​doi:10.1002/1873-3468.12158. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Conference Abstract
    ​ ​Xu XX, Tan X, Tampe B, Liu X, Maier LS, Sossalla ST, et al. ​Epigenetic balance of aberrant rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​. ​​European Journal of Heart Failure. ​2015;​17​
    Details  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Tampe B, Tampe D, Zeisberg EM, Müller GA, Bechtel-Walz W, Koziolek M, et al. ​Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease​. ​​EBioMedicine. ​2015;​2​(1):​​19​-36​. ​doi:10.1016/j.ebiom.2014.11.005. 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper
    ​ ​Charytan DM, Padera RF, Helfand AM, Zeisberg EM. ​Association of activated vitamin D use with myocardial fibrosis and capillary supply: results of an autopsy study​. ​​Renal Failure. ​2015;​37​(6):​​1067​-1069​. ​doi:10.3109/0886022X.2015.1040704. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Amanzada A, Reinhardt L, Fey D, Zeisberg EM, Mihm S. ​Hepatic Interferon-lambda 3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C​. ​​PLoS ONE. ​2015;​10​(11). ​doi:10.1371/journal.pone.0143783. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article
    ​ ​Xu X, Tan X, Tampe B, Sanchez E, Zeisberg M, Zeisberg EM. ​Snail Is a Direct Target of Hypoxia-inducible Factor 1 alpha (HIF1 alpha) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells​. ​​Journal of Biological Chemistry. ​2015;​290​(27):​​16653​-16664​. ​doi:10.1074/jbc.M115.636944. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Charytan DM, Cinelli A, Zeisberg EM. ​Association of circulating angiogenesis inhibitors and asymmetric dimethyl arginine with coronary plaque burden​. ​​Fibrogenesis & Tissue Repair. ​2015;​8​:​​1​-10​. ​doi:10.1186/s13069-015-0029-6. 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper | 
    ​ ​Gogiraju R, Xu X, Bochenek ML, Steinbrecher JH, Lehnart SE, Wenzel P, et al. ​Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice​. ​​Journal of the American Heart Association. ​2015;​4​(2):​​1​-21​. ​doi:10.1161/JAHA.115.001770. 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper
    ​ ​Xu X, Friehs I, Hu TZ, Melnychenko I, Tampe B, Alnour F, et al. ​Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​. ​​Circulation Research. ​2015;​116​(5):​​857​-866​. ​doi:10.1161/CIRCRESAHA.116.305629. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Letter Note
    ​ ​Zeisberg M, Zeisberg EM. ​Evidence for antifibrotic incretin-independent effects of the DPP-4 inhibitor linagliptin​. ​​Kidney International. ​2015;​88​(3):​​429​-431​. ​doi:10.1038/ki.2015.175. 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Zeisberg M, Zeisberg EM. ​Precision renal medicine: a roadmap towards targeted kidney fibrosis therapies​. ​​Fibrogenesis & Tissue Repair. ​2015;​8​(1). ​doi:10.1186/s13069-015-0033-x. 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper
    ​ ​Xu X, Tan X, Tampe B, Nyamsuren G, Liu X, Maier LS, et al. ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​. ​​Cardiovascular Research. ​2015;​105​(3):​​279​-291​. ​doi:10.1093/cvr/cvv015. 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Zeisberg M, Tampe B, LeBleu VS, Tampe D, Zeisberg EM, Kalluri R. ​Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure​. ​​American Journal Of Pathology. ​2014;​184​(10):​​2687​-2698​. ​doi:10.1016/j.ajpath.2014.06.014. 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Charytan DM, Padera RF, Helfand AM, Zeisberg M, Xu X, Liu X, et al. ​Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease​. ​​International Journal of Cardiology. ​2014;​176​(1):​​99​-109​. ​doi:10.1016/j.ijcard.2014.06.062. 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu VS, Xu X, et al. ​Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis​. ​​Journal of the American Society of Nephrology. ​2014;​25​(5):​​905​-912​. ​doi:10.1681/ASN.2013070723. 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article
    ​ ​Friehs I, Illigens B, Melnychenko I, Zhong-Hu T, Zeisberg EM, del Nido PJ. ​An animal model of endocardial fibroelastosis​. ​​Journal of Surgical Research. ​2013;​182​(1):​​94​-100​. ​doi:10.1016/j.jss.2012.07.069. 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Overview
    ​ ​Zeisberg EM, Zeisberg M. ​The role of promoter hypermethylation in fibroblast activation and fibrogenesis​. ​​Journal of Pathology. ​2013;​229​(2):​​264​-273​. ​doi:10.1002/path.4120. 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Conference Abstract
    ​ ​Bechtel W, McGoohan S, Zeisberg EM, Mueller G, Kalbacher H, Salant DJ, et al. ​Methylation determines fibroblast activation and fibrogenesis in the kidney​. ​​Der Internist. ​2011;​52​(6)
    Details  WoS 
  • 2011 Journal Article
    ​ ​Charytan DM, Helfand AM, MacDonald BA, Cinelli A, Kalluri R, Zeisberg EM. ​Circulating Endoglin Concentration Is Not Elevated in Chronic Kidney Disease​. ​​PLoS ONE. ​2011;​6​(8):​​e23718​. ​doi:10.1371/journal.pone.0023718. 
    Details  DOI 
  • 2010 Journal Article
    ​ ​Zeisberg EM, Kalluri R. ​Origins of Cardiac Fibroblasts​. ​​Circulation Research. ​2010;​107​(11):​​1304​-1312​. ​doi:10.1161/CIRCRESAHA.110.231910. 
    Details  DOI 
  • 2010 Journal Article
    ​ ​Krenning G, Zeisberg EM, Kalluri R. ​The origin of fibroblasts and mechanism of cardiac fibrosis​. ​​Journal of Cellular Physiology. ​2010;​225​(3):​​631​-637​. ​doi:10.1002/jcp.22322. 
    Details  DOI 
  • 2010 Journal Article | 
    ​ ​Bechtel W, McGoohan S, Zeisberg EM, Mueller GA, Kalbacher H, Salant DJ, et al. ​Methylation determines fibroblast activation and fibrogenesis in the kidney​. ​​Nature Medicine. ​2010;​16​(5):​​544​-U75​. ​doi:10.1038/nm.2135. 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. ​Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition​. ​​Journal of the American Society of Nephrology. ​2008;​19​(12):​​2282​-2287​. ​doi:10.1681/ASN.2008050513. 
    Details  DOI  PMID  PMC 
  • 2007 Journal Article | Research Paper
    ​ ​Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. ​Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts​. ​​Cancer Research. ​2007;​67​(21):​​10123​-10128​. ​doi:10.1158/0008-5472.CAN-07-3127. 
    Details  DOI  PMID  PMC 
  • 2007 Journal Article | Research Paper
    ​ ​Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, et al. ​Endothelial-to-mesenchymal transition contributes to cardiac fibrosis​. ​​Nature Medicine. ​2007;​13​(8):​​952​-961​. ​doi:10.1038/nm1613. 
    Details  DOI  PMID  PMC 
  • 2007 Journal Article
    ​ ​Tanjore H, Zeisberg EM, Gerami-Naini B, Kalluri R. ​β1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis​. ​​Developmental Dynamics. ​2007;​237​(1):​​75​-82​. ​doi:10.1002/dvdy.21385. 
    Details  DOI 
  • 2006 Journal Article
    ​ ​Kalluri R, Zeisberg E. ​Controlling angiogenesis in heart valves​. ​​Nature Medicine. ​2006;​12​(10):​​1118​-1119​. ​doi:10.1038/nm1006-1118. 
    Details  DOI 
  • 2004 Journal Article | Research Paper
    ​ ​Höcht-Zeisberg E, Kahnert H, Guan K, Wulf G, Hemmerlein B, Schlott T, et al. ​Cellular repopulation of myocardial infarction in patients with sex-mismatched heart transplantation​. ​​European heart journal. ​2004;​25​(9):​​749​-758​. ​doi:10.1016/j.ehj.2004.01.017. 
    Details  DOI  PMID  PMC  WoS 

Publication List

Type

Subtype

Date issued

Author

Project

Peer-Reviewed

Language

Fulltext

Options

Citation Style

https://publications.goettingen-research-online.de URI: /cris/rp/rp20417
ID: 0000000
PREF: vancouver TOKEN:

0

Sort

Issue Date
Title

Embed

JavaScript
Link

Export

Activate Export Mode
Deactivate Export Mode

Select some or all items (max. 800 for CSV/Excel) from the publications list, then choose an export format below.