Dr. med. Nico Horst Hartmann

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation​
    Hartmann, N. ; Preuß, L.; Mohamed, B. A. ; Schnelle, M. ; Renner, A.; Hasenfuß, G.   & Toischer, K. ​ (2022) 
    ESC Heart Failure, 9(3) pp. 1823​-1831​.​ DOI: https://doi.org/10.1002/ehf2.13877 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure​
    Bengel, P. ; Dybkova, N.; Tirilomis, P.; Ahmad, S. ; Hartmann, N. H. ; A. Mohamed, B. & Krekeler, M. C. et al.​ (2021) 
    Nature Communications, 12(1) art. 6586​.​ DOI: https://doi.org/10.1038/s41467-021-26690-1 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Status der Verfügbarkeit und Anwendung von „next generation sequencing“ (NGS) beim Harnblasenkarzinom – eine Umfrage in der Arbeitsgemeinschaft Uropathologie​
    Ortiz-Brüchle, N.; Muders, M.; Toma, M.; Esposito, I.; Hartmann, A.; Stöhr, R. & Reis, H. et al.​ (2019) 
    Der Urologe, 59(3) pp. 318​-325​.​ DOI: https://doi.org/10.1007/s00120-019-01046-2 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy​
    Ahmad, S. ; Tirilomis, P.; Pabel, S. ; Dybkova, N.; Hartmann, N. ; Molina, C. E.   & Tirilomis, T.  et al.​ (2019) 
    ESC Heart Failure, 6(1) pp. 154​-163​.​ DOI: https://doi.org/10.1002/ehf2.12378 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart​
    Dybkova, N.; Ahmad, S. ; Pabel, S. ; Tirilomis, P.; Hartmann, N. ; Fischer, T. H   & Bengel, P.  et al.​ (2018) 
    Cardiovascular Research, 114(13) pp. 1728​-1737​.​ DOI: https://doi.org/10.1093/cvr/cvy152 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​
    Mohamed, B. A. ; Hartmann, N. ; Tirilomis, P.; Sekeres, K.; Li, W.; Neef, S. & Richter, C.  et al.​ (2018) 
    Science Translational Medicine, 10(458) art. eaan0724​.​ DOI: https://doi.org/10.1126/scitranslmed.aan0724 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology​
    Hartmann, N. H. ; Mason, F. E. ; Braun, I.; Pabel, S. ; Voigt, N. ; Schotola, H. & Fischer, T. H.  et al.​ (2016) 
    Journal of Molecular and Cellular Cardiology, 94 pp. 95​-106​.​ DOI: https://doi.org/10.1016/j.yjmcc.2016.03.012 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes​
    Hartmann, N. H. ; Pabel, S. ; Herting, J. ; Schatter, F. ; Renner, A.; Gummert, J. & Schotola, H. et al.​ (2016) 
    Heart Rhythm, 14(3) pp. 412​-419​.​ DOI: https://doi.org/10.1016/j.hrthm.2016.09.014 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​Enhanced cardiac TBC1D10C expression lowers heart rate and enhances exercise capacity and survival​
    Volland, C.; Bremer, S. ; Hellenkamp, K. ; Hartmann, N. H. ; Dybkova, N.; Khadjeh, S.   & Kutschenko, A. et al.​ (2016) 
    Scientific Reports, 6 art. 33853​.​ DOI: https://doi.org/10.1038/srep33853 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure​
    Fischer, T. H. ; Herting, J. ; Eiringhaus, J. ; Pabel, S. ; Hartmann, N. H. ; Ellenberger, D.   & Friedrich, M.  et al.​ (2016) 
    EP Europace, 18(9) pp. 1440​-1448​.​ DOI: https://doi.org/10.1093/europace/euv313 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Inhibition of CaMKII Attenuates Progressing Disruption of Ca2+ Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure​
    Fischer, T. H. ; Kleinwächter, A.; Herting, J. ; Eiringhaus, J. ; Hartmann, N. ; Renner, A. & Gummert, J. et al.​ (2016) 
    Artificial Organs, 40(8) pp. 719​-726​.​ DOI: https://doi.org/10.1111/aor.12677 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII​
    Fischer, T. H. ; Herting, J. ; Mason, F. E. ; Hartmann, N. ; Watanabe, S.; Nikolaev, V. O.   & Sprenger, J. U. et al.​ (2015) 
    Cardiovascular Research, 107(1) pp. 184​-196​.​ DOI: https://doi.org/10.1093/cvr/cvv153 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner​
    Sag, C. M.; Mallwitz, A.; Wagner, S. ; Hartmann, N. ; Schotola, H.; Fischer, T. H.   & Ungeheuer, N. et al.​ (2014) 
    Journal of Molecular and Cellular Cardiology, 76 pp. 94​-105​.​ DOI: https://doi.org/10.1016/j.yjmcc.2014.08.016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease​
    Toischer, K. ; Hartmann, N. ; Wagner, S. ; Fischer, T. H. ; Herting, J. ; Danner, B. C.   & Sag, C. M. et al.​ (2013) 
    Journal of Molecular and Cellular Cardiology, 61 pp. 111​-122​.​ DOI: https://doi.org/10.1016/j.yjmcc.2013.03.021 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper | 
    ​ ​Diastolic dysfunction and arrhythmias caused by overexpression of CaMKII delta(C) can be reversed by inhibition of late Na+ current​
    Sossalla, S. ; Maurer, U.; Schotola, H.; Hartmann, N. H. ; Didie, M. ; Zimmermann, W.-H.   & Jacobshagen, C.  et al.​ (2011) 
    Basic Research in Cardiology, 106(2) pp. 263​-272​.​ DOI: https://doi.org/10.1007/s00395-010-0136-x 
    ​Details  DOI  PMID  PMC  WoS 

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