Dr. Thomas Prukop

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unigoe
 

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  • 2020 | Journal Article
    ​ ​Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot–Marie–Tooth disease type 1A (CMT1A) rats​
    Prukop, T. ; Wernick, S.; Boussicault, L.; Ewers, D.; Jäger, K.; Adam, J. & Winter, L. et al.​ (2020) 
    Journal of Neuroscience Research, 98(10) pp. 1933​-1952​.​ DOI: https://doi.org/10.1002/jnr.24679 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil​
    Matthaei, J. ; Seitz, T. ; Jensen, O. ; Tann, A.; Prukop, T. ; Tadjerpisheh, S. & Brockmöller, J.  et al.​ (2019) 
    Clinical Pharmacology and Therapeutics, 105(1) pp. 190​-200​.​ DOI: https://doi.org/10.1002/cpt.1128 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A​
    Rafehi, M. ; Faltraco, F.; Matthaei, J. ; Prukop, T. ; Jensen, O. ; Grytzmann, A. & Berger, R. G. et al.​ (2019) 
    Frontiers in Pharmacology, 10 pp. 1297​.​ DOI: https://doi.org/10.3389/fphar.2019.01297 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy​
    Fledrich, R. ; Abdelaal, T.; Rasch, L.; Bansal, V.; Schütza, V.; Brügger, B. & Lüchtenborg, C. et al.​ (2018) 
    Nature Communications, 9(1).​ DOI: https://doi.org/10.1038/s41467-018-05420-0 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency​
    Tzvetkov, M. V. ; Matthaei, J. ; Pojar, S.; Faltraco, F.; Vogler, S.; Prukop, T.   & Seitz, T.  et al.​ (2017) 
    Clinical Pharmacology & Therapeutics, 103(5) pp. 868​-878​.​ DOI: https://doi.org/10.1002/cpt.812 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A​
    Fledrich, R.; Stassart, R. M.; Klink, A.; Rasch, L. M.; Prukop, T. ; Haag, L. & Czesnik, D. et al.​ (2014) 
    Nature Medicine, 20(9) pp. 1055​-1061​.​ DOI: https://doi.org/10.1038/nm.3664 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy​
    Meyer zu Hörste, G.; Prukop, T. ; Liebetanz, D. ; Möbius, W. ; Nave, K.-A.   & Sereda, M. W. ​ (2007) 
    Annals of Neurology, 61(1) pp. 61​-72​.​ DOI: https://doi.org/10.1002/ana.21026 
    ​Details  DOI  WoS 

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https://publications.goettingen-research-online.de URI: /cris/rp/rp72709
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