RG Schuh

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  • 2024 | Journal Article
    ​ ​Mouse oocytes sequester aggregated proteins in degradative super-organelles​
    Zaffagnini, G.; Cheng, S.; Salzer, M. C.; Pernaute, B.; Duran, J. M.; Irimia, M. & Schuh, M. et al.​ (2024) 
    Cell, 187(5) pp. 1109​-1126.e21​.​ DOI: https://doi.org/10.1016/j.cell.2024.01.031 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes​
    Harasimov, K.; Uraji, J.; Mönnich, E. U.; Holubcová, Z.; Elder, K.; Blayney, M. & Schuh, M.​ (2023) 
    Nature Cell Biology,.​ DOI: https://doi.org/10.1038/s41556-022-01082-9 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices​
    Jentoft, I. M. A.; Bäuerlein, F. J. B.; Welp, L. M.; Cooper, B. H.; Petrovic, A.; So, C. & Penir, S. M. et al.​ (2023) 
    Cell, 186(24) pp. 5308​-5327.e25​.​ DOI: https://doi.org/10.1016/j.cell.2023.10.003 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Overview
    ​ ​Aneuploidy in mammalian oocytes and the impact of maternal ageing​
    Charalambous, C.; Webster, A. & Schuh, M. ​ (2022) 
    Nature Reviews Molecular Cell Biology, pp. 27​-44​.​ DOI: https://doi.org/10.1038/s41580-022-00517-3 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article
    ​ ​Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment​
    Cheng, S.; Altmeppen, G.; So, C.; Welp, L. M.; Penir, S.; Ruhwedel, T. & Menelaou, K. et al.​ (2022) 
    Science, 378(6617) art. eabq4835​.​ DOI: https://doi.org/10.1126/science.abq4835 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Mechanism of spindle pole organization and instability in human oocytes​
    So, C.; Menelaou, K.; Uraji, J.; Harasimov, K.; Steyer, A. M.; Seres, K. B. & Bucevičius, J. et al.​ (2022) 
    Science, 375(6581) art. eabj3944​.​ DOI: https://doi.org/10.1126/science.abj3944 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Parental genome unification is highly error-prone in mammalian embryos​
    Cavazza, T.; Takeda, Y.; Politi, A. Z.; Aushev, M.; Aldag, P.; Baker, C. & Choudhary, M. et al.​ (2021) 
    Cell, 184(11) pp. 2860.e22​-2877.e22​.​ DOI: https://doi.org/10.1016/j.cell.2021.04.013 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Origins and mechanisms leading to aneuploidy in human eggs​
    Wartosch, L.; Schindler, K.; Schuh, M. ; Gruhn, J. R.; Hoffmann, E. R.; McCoy, R. C. & Xing, J.​ (2021) 
    Prenatal Diagnosis, 41(5) pp. 620​-630​.​ DOI: https://doi.org/10.1002/pd.5927 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Two mechanisms drive pronuclear migration in mouse zygotes​
    Scheffler, K.; Uraji, J.; Jentoft, I.; Cavazza, T.; Mönnich, E.; Mogessie, B. & Schuh, M. ​ (2021) 
    Nature Communications, 12(1) pp. 841​.​ DOI: https://doi.org/10.1038/s41467-021-21020-x 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Aneuploidy in human eggs: contributions of the meiotic spindle​
    Thomas, C.; Cavazza, T. & Schuh, M. ​ (2021) 
    Biochemical Society Transactions, 49(1) pp. 107​-118​.​ DOI: https://doi.org/10.1042/BST20200043 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Phase Separation during Germline Development​
    So, C.; Cheng, S. & Schuh, M. ​ (2021) 
    Trends in Cell Biology, 31(4) pp. 254​-268​.​ DOI: https://doi.org/10.1016/j.tcb.2020.12.004 
    ​Details  DOI  PMID  PMC 
  • 2020 | Preprint
    ​ ​Parental genome unification is highly erroneous in mammalian embryos​
    Cavazza, T.; Politi, A. Z.; Aldag, P.; Baker, C.; Elder, K.; Blayney, M.& Lucas-Hahn, A. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.27.269779 
    ​Details  DOI 

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