RG E. Zeisberg (Kardiales Stroma)

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  • 2024 | Journal Article
    ​ ​Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function​
    Gersch, S.; Lange, T.; Beuthner, B. E.; Elkenani, M.; Paul, N.; Schnelle, M. & Zeisberg, E. et al.​ (2024) 
    Clinical Research in Cardiology,.​ DOI: https://doi.org/10.1007/s00392-023-02372-4 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article | 
    ​ ​Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement​
    Beuthner, B. E.; Elkenani, M.; Evert, K.; Mustroph, J.; Jacob, C. F.; Paul, N. B. & Beißbarth, T. et al.​ (2024) 
    ESC Heart Failure, art. ehf2.14709​.​ DOI: https://doi.org/10.1002/ehf2.14709 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis​
    Kanwischer, L.; Xu, X.; Saifuddin, A. B.; Maamari, S.; Tan, X.; Alnour, F. & Tampe, B. et al.​ (2023) 
    Clinical Epigenetics, 15(1) art. 149​.​ DOI: https://doi.org/10.1186/s13148-023-01561-2 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies​
    Hoffmann, J.; Hanß, S.; Kraus, M.; Schaller, J.; Schäfer, C.; Stahl, D. & Anker, S. D. et al.​ (2023) 
    Clinical Research in Cardiology,.​ DOI: https://doi.org/10.1007/s00392-023-02177-5 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes​
    Dai, Y.; Ignatyeva, N.; Xu, H.; Wali, R.; Toischer, K.; Brandenburg, S. & Lenz, C. et al.​ (2023) 
    Circulation Research, art. CIRCRESAHA.122.321157​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.122.321157 
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  • 2023 | Journal Article | 
    ​ ​Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement​
    Evertz, R.; Hub, S.; Beuthner, B. E.; Backhaus, S. J.; Lange, T.; Schulz, A. & Toischer, K. et al.​ (2023) 
    ESC Heart Failure, art. ehf2.14307​.​ DOI: https://doi.org/10.1002/ehf2.14307 
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  • 2021 | Journal Article | Research Paper | 
    ​ ​Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes​
    Michurina, A.; Sakib, M S.; Kerimoglu, C. ; Krüger, D. M.; Kaurani, L. ; Islam, M. R. & Joshi, P. D. et al.​ (2021) 
    The EMBO Journal,.​ DOI: https://doi.org/10.15252/embj.2020106459 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis​
    Puls, M.; Beuthner, B. E.; Topci, R.; Vogelgesang, A.; Bleckmann, A.; Sitte, M. & Lange, T. et al.​ (2020) 
    European Heart Journal, 41(20) pp. 1903​-1914​.​ DOI: https://doi.org/10.1093/eurheartj/ehaa033 
    ​Details  DOI  PMID  PMC 
  • 2020 | Preprint
    ​ ​SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​
    Michurina, A.; Sakib, S.; Kerimoglu, C.; Krüger, D. M.; Kaurani, L.; Islam, R.& Centeno, T. P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.07.240853 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement​
    Beuthner, B. E. C.; Topci, R.; Derks, M.; Franke, T.; Seelke, S.; Puls, M. & Schuster, A. et al.​ (2020) 
    Open Journal of Bioresources, 7.​ DOI: https://doi.org/10.5334/ojb.65 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis​
    Backhaus, S. J. ; Lange, T.; Beuthner, B. E.; Topci, R.; Wang, X.; Kowallick, J. T.   & Lotz, J.  et al.​ (2020) 
    Journal of Cardiovascular Magnetic Resonance, 22(1) pp. 46​.​ DOI: https://doi.org/10.1186/s12968-020-00632-0 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure​
    Tampe, B. ; Tampe, D. ; Nyamsuren, G.; Klöpper, F.; Rapp, G.; Kauffels, A.   & Lorf, T.  et al.​ (2018) 
    The Journal of Clinical Investigation, 128(7) pp. 3053​-3070​.​ DOI: https://doi.org/10.1172/JCI89632 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Wilhelmi, T.; Hulshoff, M. S.; Saito, S. & Moser, T.  et al.​ (2018) 
    Nature Communications, 9(1) art. 3509​.​ DOI: https://doi.org/10.1038/s41467-018-05766-5 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​
    Mohamed, B. A. ; Hartmann, N. ; Tirilomis, P.; Sekeres, K.; Li, W.; Neef, S. & Richter, C.  et al.​ (2018) 
    Science Translational Medicine, 10(458) art. eaan0724​.​ DOI: https://doi.org/10.1126/scitranslmed.aan0724 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper
    ​ ​Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression​
    Tampe, B. ; Steinle, U.; Tampe, D. ; Carstens, J. L.; Korsten, P. ; Zeisberg, E. M.   & Müller, G. A. et al.​ (2017) 
    Kidney International, 91(1) pp. 157​-176​.​ DOI: https://doi.org/10.1016/j.kint.2016.07.042 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​
    Tan, X.; Xu, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2016) 
    PLoS ONE, 11(1) art. e0147816​.​ DOI: https://doi.org/10.1371/journal.pone.0147816 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​
    Tan, X.; Xu, X.; Zeisberg, E. M.   & Zeisberg, M. ​ (2016) 
    Biochemical and Biophysical Research Communications, 472(3) pp. 459​-464​.​ DOI: https://doi.org/10.1016/j.bbrc.2016.01.077 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice​
    Gogiraju, R.; Xu, X.; Bochenek, M. L.; Steinbrecher, J. H.; Lehnart, S. E. ; Wenzel, P. & Kessel, M.  et al.​ (2015) 
    Journal of the American Heart Association, 4(2) art. e001770​.​ DOI: https://doi.org/10.1161/JAHA.115.001770 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper
    ​ ​Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​
    Xu, X.; Friehs, I.; Hu, T. Z.; Melnychenko, I.; Tampe, B. ; Alnour, F.   & Iascone, M. et al.​ (2015) 
    Circulation Research, 116(5) pp. 857​-866​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.116.305629 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Nyamsuren, G.; Liu, X.; Maier, L. S.   & Sossalla, S.  et al.​ (2015) 
    Cardiovascular Research, 105(3) pp. 279​-291​.​ DOI: https://doi.org/10.1093/cvr/cvv015 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease​
    Tampe, B. ; Tampe, D. ; Zeisberg, E. M. ; Müller, G. A. ; Bechtel-Walz, W.; Koziolek, M.   & Kalluri, R. et al.​ (2015) 
    EBioMedicine, 2(1) pp. 19​-36​.​ DOI: https://doi.org/10.1016/j.ebiom.2014.11.005 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Hepatic Interferon-lambda 3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C​
    Amanzada, A.; Reinhardt, L.; Fey, D.; Zeisberg, E. M.   & Mihm, S.​ (2015) 
    PLoS ONE, 10(11) art. e0143783​.​ DOI: https://doi.org/10.1371/journal.pone.0143783 
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  • 2015 | Journal Article | Research Paper
    ​ ​Association of activated vitamin D use with myocardial fibrosis and capillary supply: results of an autopsy study​
    Charytan, D. M.; Padera, R. F.; Helfand, A. M. & Zeisberg, E. M. ​ (2015) 
    Renal Failure, 37(6) pp. 1067​-1069​.​ DOI: https://doi.org/10.3109/0886022X.2015.1040704 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Association of circulating angiogenesis inhibitors and asymmetric dimethyl arginine with coronary plaque burden​
    Charytan, D. M.; Cinelli, A. & Zeisberg, E. M. ​ (2015) 
    Fibrogenesis & Tissue Repair, 8 art. 13​.​ DOI: https://doi.org/10.1186/s13069-015-0029-6 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | Research Paper
    ​ ​Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease​
    Charytan, D. M.; Padera, R. F.; Helfand, A. M.; Zeisberg, M. ; Xu, X.; Liu, X. & Himmelfarb, J. et al.​ (2014) 
    International Journal of Cardiology, 176(1) pp. 99​-109​.​ DOI: https://doi.org/10.1016/j.ijcard.2014.06.062 
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  • 2014 | Journal Article | Research Paper
    ​ ​Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure​
    Zeisberg, M. ; Tampe, B.; LeBleu, V. S.; Tampe, D. ; Zeisberg, E. M.   & Kalluri, R.​ (2014) 
    American Journal Of Pathology, 184(10) pp. 2687​-2698​.​ DOI: https://doi.org/10.1016/j.ajpath.2014.06.014 
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  • 2014 | Journal Article | Research Paper
    ​ ​Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis​
    Tampe, B. ; Tampe, D. ; Müller, C. A.; Sugimoto, H.; LeBleu, V. S.; Xu, X. & Müller, G. A. et al.​ (2014) 
    Journal of the American Society of Nephrology, 25(5) pp. 905​-912​.​ DOI: https://doi.org/10.1681/ASN.2013070723 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Overview
    ​ ​The role of promoter hypermethylation in fibroblast activation and fibrogenesis​
    Zeisberg, E. M.   & Zeisberg, M. ​ (2013) 
    Journal of Pathology, 229(2) pp. 264​-273​.​ DOI: https://doi.org/10.1002/path.4120 
    ​Details  DOI  PMID  PMC  WoS 

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