RG E. Zeisberg (Kardiales Stroma)

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  • 2024 | Journal Article
    ​ ​Gersch, Svante, Torben Lange, Bo Eric Beuthner, Manar Elkenani, Niels Paul, Moritz Schnelle, Elisabeth Zeisberg et al. "Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function​." ​Clinical Research in Cardiology (2024): . ​https://doi.org/10.1007/s00392-023-02372-4.
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  • 2024 | Journal Article | 
    ​ ​Beuthner, Bo Eric, Manar Elkenani, Katja Evert, Julian Mustroph, Christoph Friedemann Jacob, Niels Benjamin Paul, Tim Beißbarth et al. "Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement​." ​ESC Heart Failure (2024): ​ehf2.14709​. ​https://doi.org/10.1002/ehf2.14709.
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  • 2023 | Journal Article | 
    ​ ​Kanwischer, Leon, Xingbo Xu, Afifa B. Saifuddin, Sabine Maamari, Xiaoying Tan, Fouzi Alnour, Björn Tampe et al. "Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis​." ​Clinical Epigenetics ​15, no. 1 (2023): ​149​. ​https://doi.org/10.1186/s13148-023-01561-2.
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  • 2023 | Journal Article | 
    ​ ​Hoffmann, Julia, Sabine Hanß, Monika Kraus, Jens Schaller, Christian Schäfer, Dana Stahl, Stefan D. Anker et al. "The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies​." ​Clinical Research in Cardiology (2023): . ​https://doi.org/10.1007/s00392-023-02177-5.
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  • 2023 | Journal Article | 
    ​ ​Evertz, Ruben, Sebastian Hub, Bo Eric Beuthner, Sören J. Backhaus, Torben Lange, Alexander Schulz, Karl Toischer et al. "Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement​." ​ESC Heart Failure (2023): ​ehf2.14307​. ​https://doi.org/10.1002/ehf2.14307.
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  • 2023 | Journal Article
    ​ ​Dai, Yuanyuan, Nadezda Ignatyeva, Hang Xu, Ruheen Wali, Karl Toischer, Sören Brandenburg, Christof Lenz et al. "An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes​." ​Circulation Research (2023): ​CIRCRESAHA.122.321157​. ​https://doi.org/10.1161/CIRCRESAHA.122.321157.
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  • 2021 | Journal Article | Research Paper | 
    ​ ​Michurina, Alexandra, M Sadman Sakib, Cemil Kerimoglu, Dennis Manfred Krüger, Lalit Kaurani, Md Rezaul Islam, Parth Devesh Joshi et al. "Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes​." ​The EMBO Journal (2021): . ​https://doi.org/10.15252/embj.2020106459.
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  • 2020 | Journal Article | Research Paper | 
    ​ ​Puls, Miriam, Bo Eric Beuthner, Rodi Topci, Anja Vogelgesang, Annalen Bleckmann, Maren Sitte, Torben Lange et al. "Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis​." ​European Heart Journal ​41, no. 20 (2020): ​1903​-1914​. ​https://doi.org/10.1093/eurheartj/ehaa033.
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  • 2020 | Preprint
    ​ ​Michurina, Alexandra, Sadman Sakib, Cemil Kerimoglu, Dennis Manfred Krüger, Lalit Kaurani, Rezaul Islam, Tonatiuh Pena Centeno et al​. "SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​." ​Preprint, submitted ​​2020. https://doi.org/10.1101/2020.08.07.240853.
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  • 2020 | Journal Article | Research Paper | 
    ​ ​Beuthner, Bo E. C., Rodi Topci, Mareike Derks, Thomas Franke, Sandra Seelke, Miriam Puls, Andreas Schuster et al. "Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement​." ​Open Journal of Bioresources ​7 (2020): . ​https://doi.org/10.5334/ojb.65.
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  • 2020 | Journal Article | Research Paper | 
    ​ ​Backhaus, Sören Jan, Torben Lange, Bo Eric Beuthner, Rodi Topci, Xiaoqing Wang, Johannes Tammo Kowallick, Joachim Lotz et al. "Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis​." ​Journal of Cardiovascular Magnetic Resonance ​22, no. 1 (2020): ​46​. ​https://doi.org/10.1186/s12968-020-00632-0.
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  • 2018 | Journal Article | Research Paper
    ​ ​Mohamed, Belal A., Nico Hartmann, Petros Tirilomis, Karolina Sekeres, Wener Li, Stefan Neef, Claudia Richter et al. "Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​." ​Science Translational Medicine ​10, no. 458 (2018): ​eaan0724​. ​https://doi.org/10.1126/scitranslmed.aan0724.
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  • 2018 | Journal Article | Research Paper | 
    ​ ​Tampe, Björn, Désirée Tampe, Gunsmaa Nyamsuren, Friederike Klöpper, Gregor Rapp, Anne Kauffels, Thomas Lorf et al. "Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure​." ​The Journal of Clinical Investigation ​128, no. 7 (2018): ​3053​-3070​. ​https://doi.org/10.1172/JCI89632.
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  • 2018 | Journal Article | Research Paper | 
    ​ ​Xu, Xingbo, Xiaoying Tan, Björn Tampe, Tim Wilhelmi, Melanie S. Hulshoff, Shoji Saito, Tobias Moser et al. "High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​." ​Nature Communications ​9, no. 1 (2018): ​3509​. ​https://doi.org/10.1038/s41467-018-05766-5.
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  • 2017 | Journal Article | Research Paper
    ​ ​Tampe, Björn, Ulrike Steinle, Désirée Tampe, Julienne L. Carstens, Peter Korsten, Elisabeth M. Zeisberg, Gerhard A. Müller, Raghu Kalluri, and Michael Zeisberg. "Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression​." ​Kidney International ​91, no. 1 (2017): ​157​-176​. ​https://doi.org/10.1016/j.kint.2016.07.042.
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  • 2016 | Journal Article | Research Paper | 
    ​ ​Tan, Xiaoying, Xingbo Xu, Michael Zeisberg, and Elisabeth M. Zeisberg. "DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​." ​PLoS ONE ​11, no. 1 (2016): ​e0147816​. ​https://doi.org/10.1371/journal.pone.0147816.
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  • 2016 | Journal Article | Research Paper
    ​ ​Tan, Xiaoying, X. Xu, Elisabeth M. Zeisberg, and Michael Zeisberg. "High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​." ​Biochemical and Biophysical Research Communications ​472, no. 3 (2016): ​459​-464​. ​https://doi.org/10.1016/j.bbrc.2016.01.077.
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  • 2015 | Journal Article | Research Paper | 
    ​ ​Tampe, Björn, Desiree Tampe, Elisabeth M. Zeisberg, Gerhard A. Müller, Wibke Bechtel-Walz, Michael Koziolek, Raghu Kalluri, and Michael Zeisberg. "Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease​." ​EBioMedicine ​2, no. 1 (2015): ​19​-36​. ​https://doi.org/10.1016/j.ebiom.2014.11.005.
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  • 2015 | Journal Article | Research Paper
    ​ ​Charytan, David M., Robert F. Padera, Alexander M. Helfand, and Elisabeth M. Zeisberg. "Association of activated vitamin D use with myocardial fibrosis and capillary supply: results of an autopsy study​." ​Renal Failure ​37, no. 6 (2015): ​1067​-1069​. ​https://doi.org/10.3109/0886022X.2015.1040704.
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  • 2015 | Journal Article | Research Paper | 
    ​ ​Charytan, David M., Angeles Cinelli, and Elisabeth M. Zeisberg. "Association of circulating angiogenesis inhibitors and asymmetric dimethyl arginine with coronary plaque burden​." ​Fibrogenesis & Tissue Repair ​8 (2015): ​13​. ​https://doi.org/10.1186/s13069-015-0029-6.
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  • 2015 | Journal Article | Research Paper | 
    ​ ​Gogiraju, Rajinikanth, Xingbo Xu, Magdalena L. Bochenek, Julia H. Steinbrecher, Stephan E. Lehnart, Philip Wenzel, Michael Kessel, Elisabeth M. Zeisberg, Matthias Dobbelstein, and Katrin Schäfer. "Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice​." ​Journal of the American Heart Association ​4, no. 2 (2015): ​e001770​. ​https://doi.org/10.1161/JAHA.115.001770.
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  • 2015 | Journal Article | Research Paper
    ​ ​Xu, Xingbo, Xiaoying Tan, Bjoern Tampe, Gunsmaa Nyamsuren, Xiaopeng Liu, Lars S. Maier, Samuel Sossalla et al. "Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​." ​Cardiovascular Research ​105, no. 3 (2015): ​279​-291​. ​https://doi.org/10.1093/cvr/cvv015.
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  • 2015 | Journal Article | Research Paper
    ​ ​Xu, Xingbo, Ingeborg Friehs, Tachi Zhong Hu, Ivan Melnychenko, Björn Tampe, Fouzi Alnour, Maria Iascone et al. "Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​." ​Circulation Research ​116, no. 5 (2015): ​857​-866​. ​https://doi.org/10.1161/CIRCRESAHA.116.305629.
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  • 2015 | Journal Article | Research Paper | 
    ​ ​Amanzada, Ahmad, Lars Reinhardt, Dorothea Fey, Elisabeth M. Zeisberg, and Sabine Mihm. "Hepatic Interferon-lambda 3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C​." ​PLoS ONE ​10, no. 11 (2015): ​e0143783​. ​https://doi.org/10.1371/journal.pone.0143783.
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  • 2014 | Journal Article | Research Paper
    ​ ​Tampe, Björn, Desiree Tampe, Claudia A. Müller, Hikaru Sugimoto, Valerie S. LeBleu, X. Xu, Georg Anton Müller, Elisabeth M. Zeisberg, Raghu Kalluri, and Michael Zeisberg. "Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis​." ​Journal of the American Society of Nephrology ​25, no. 5 (2014): ​905​-912​. ​https://doi.org/10.1681/ASN.2013070723.
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  • 2014 | Journal Article | Research Paper
    ​ ​Charytan, David M., Robert F. Padera, Alexander M. Helfand, Michael Zeisberg, X. Xu, Xiaopeng Liu, Jonathan Himmelfarb, Angeles Cinelli, Raghu Kalluri, and Elisabeth M. Zeisberg. "Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease​." ​International Journal of Cardiology ​176, no. 1 (2014): ​99​-109​. ​https://doi.org/10.1016/j.ijcard.2014.06.062.
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  • 2014 | Journal Article | Research Paper
    ​ ​Zeisberg, Michael, Bjoern Tampe, Valerie S. LeBleu, Desiree Tampe, Elisabeth M. Zeisberg, and Raghu Kalluri. "Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure​." ​American Journal Of Pathology ​184, no. 10 (2014): ​2687​-2698​. ​https://doi.org/10.1016/j.ajpath.2014.06.014.
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  • 2013 | Journal Article | Overview
    ​ ​Zeisberg, Elisabeth M., and Michael Zeisberg. "The role of promoter hypermethylation in fibroblast activation and fibrogenesis​." ​Journal of Pathology ​229, no. 2 (2013): ​264​-273​. ​https://doi.org/10.1002/path.4120.
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