RG M. Zeisberg (Renale Fibrogenese)

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  • 2021 | Journal Article | Research Paper | 
    ​ ​Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition​
    Hakroush, S.; Kopp, S. B.; Tampe, D. ; Gersmann, A.-K.; Korsten, P. ; Zeisberg, M.   & Tampe, B. ​ (2021) 
    Frontiers in Immunology, 11.​ DOI: https://doi.org/10.3389/fimmu.2020.624547 
    ​Details  DOI 
  • 2018 | Journal Article | Overview
    ​ ​Chromatin dynamics at the core of kidney fibrosis​
    Tampe, B.   & Zeisberg, M. ​ (2018) 
    Matrix Biology, 68-69 pp. 194​-229​.​ DOI: https://doi.org/10.1016/j.matbio.2018.02.015 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure​
    Tampe, B. ; Tampe, D. ; Nyamsuren, G.; Klöpper, F.; Rapp, G.; Kauffels, A.   & Lorf, T.  et al.​ (2018) 
    The Journal of Clinical Investigation, 128(7) pp. 3053​-3070​.​ DOI: https://doi.org/10.1172/JCI89632 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Wilhelmi, T.; Hulshoff, M. S.; Saito, S. & Moser, T.  et al.​ (2018) 
    Nature Communications, 9(1) art. 3509​.​ DOI: https://doi.org/10.1038/s41467-018-05766-5 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper
    ​ ​Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression​
    Tampe, B. ; Steinle, U.; Tampe, D. ; Carstens, J. L.; Korsten, P. ; Zeisberg, E. M.   & Müller, G. A. et al.​ (2017) 
    Kidney International, 91(1) pp. 157​-176​.​ DOI: https://doi.org/10.1016/j.kint.2016.07.042 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​
    Tan, X.; Xu, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2016) 
    PLoS ONE, 11(1) art. e0147816​.​ DOI: https://doi.org/10.1371/journal.pone.0147816 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​
    Tan, X.; Xu, X.; Zeisberg, E. M.   & Zeisberg, M. ​ (2016) 
    Biochemical and Biophysical Research Communications, 472(3) pp. 459​-464​.​ DOI: https://doi.org/10.1016/j.bbrc.2016.01.077 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​
    Xu, X.; Friehs, I.; Hu, T. Z.; Melnychenko, I.; Tampe, B. ; Alnour, F.   & Iascone, M. et al.​ (2015) 
    Circulation Research, 116(5) pp. 857​-866​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.116.305629 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Nyamsuren, G.; Liu, X.; Maier, L. S.   & Sossalla, S.  et al.​ (2015) 
    Cardiovascular Research, 105(3) pp. 279​-291​.​ DOI: https://doi.org/10.1093/cvr/cvv015 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease​
    Tampe, B. ; Tampe, D. ; Zeisberg, E. M. ; Müller, G. A. ; Bechtel-Walz, W.; Koziolek, M.   & Kalluri, R. et al.​ (2015) 
    EBioMedicine, 2(1) pp. 19​-36​.​ DOI: https://doi.org/10.1016/j.ebiom.2014.11.005 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | Research Paper
    ​ ​Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease​
    Charytan, D. M.; Padera, R. F.; Helfand, A. M.; Zeisberg, M. ; Xu, X.; Liu, X. & Himmelfarb, J. et al.​ (2014) 
    International Journal of Cardiology, 176(1) pp. 99​-109​.​ DOI: https://doi.org/10.1016/j.ijcard.2014.06.062 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure​
    Zeisberg, M. ; Tampe, B.; LeBleu, V. S.; Tampe, D. ; Zeisberg, E. M.   & Kalluri, R.​ (2014) 
    American Journal Of Pathology, 184(10) pp. 2687​-2698​.​ DOI: https://doi.org/10.1016/j.ajpath.2014.06.014 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis​
    Tampe, B. ; Tampe, D. ; Müller, C. A.; Sugimoto, H.; LeBleu, V. S.; Xu, X. & Müller, G. A. et al.​ (2014) 
    Journal of the American Society of Nephrology, 25(5) pp. 905​-912​.​ DOI: https://doi.org/10.1681/ASN.2013070723 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Overview
    ​ ​The role of promoter hypermethylation in fibroblast activation and fibrogenesis​
    Zeisberg, E. M.   & Zeisberg, M. ​ (2013) 
    Journal of Pathology, 229(2) pp. 264​-273​.​ DOI: https://doi.org/10.1002/path.4120 
    ​Details  DOI  PMID  PMC  WoS 

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