RG M. Zeisberg (Renale Fibrogenese)

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  • 2021 | Journal Article | Research Paper | 
    ​ ​Hakroush S, Kopp SB, Tampe D, Gersmann, Ann-Kathrin, Korsten P, Zeisberg M, et al. ​Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition​. ​​Frontiers in Immunology. ​2021;​11​. ​doi:10.3389/fimmu.2020.624547. 
    ​Details  DOI 
  • 2018 | Journal Article | Overview
    ​ ​Tampe B, Zeisberg M. ​Chromatin dynamics at the core of kidney fibrosis​. ​​Matrix Biology. ​2018;​68-69​:​​194​-229​. ​doi:10.1016/j.matbio.2018.02.015. 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Tampe B, Tampe D, Nyamsuren G, Klöpper F, Rapp G, Kauffels A, et al. ​Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure​. ​​The Journal of Clinical Investigation. ​2018;​128​(7):​​3053​-3070​. ​doi:10.1172/JCI89632. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff MS, Saito S, et al. ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​. ​​Nature Communications. ​2018;​9​(1):​​1​-15​. ​doi:10.1038/s41467-018-05766-5. 
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  • 2017 | Journal Article | Research Paper
    ​ ​Tampe B, Steinle U, Tampe D, Carstens JL, Korsten P, Zeisberg EM, et al. ​Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression​. ​​Kidney International. ​2017;​91​(1):​​157​-176​. ​doi:10.1016/j.kint.2016.07.042. 
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  • 2016 | Journal Article | Research Paper
    ​ ​Tan X, Xu X, Zeisberg EM, Zeisberg M. ​High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​. ​​Biochemical and Biophysical Research Communications. ​2016;​472​(3):​​459​-464​. ​doi:10.1016/j.bbrc.2016.01.077. 
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  • 2016 | Journal Article | Research Paper | 
    ​ ​Tan X, Xu X, Zeisberg M, Zeisberg EM. ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​. ​​PLoS ONE. ​2016;​11​(1):​​1​-17​. ​doi:10.1371/journal.pone.0147816. 
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  • 2015 | Journal Article | Research Paper | 
    ​ ​Tampe B, Tampe D, Zeisberg EM, Müller GA, Bechtel-Walz W, Koziolek M, et al. ​Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease​. ​​EBioMedicine. ​2015;​2​(1):​​19​-36​. ​doi:10.1016/j.ebiom.2014.11.005. 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper
    ​ ​Xu X, Tan X, Tampe B, Nyamsuren G, Liu X, Maier LS, et al. ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​. ​​Cardiovascular Research. ​2015;​105​(3):​​279​-291​. ​doi:10.1093/cvr/cvv015. 
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  • 2015 | Journal Article | Research Paper
    ​ ​Xu X, Friehs I, Hu TZ, Melnychenko I, Tampe B, Alnour F, et al. ​Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​. ​​Circulation Research. ​2015;​116​(5):​​857​-866​. ​doi:10.1161/CIRCRESAHA.116.305629. 
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  • 2014 | Journal Article | Research Paper
    ​ ​Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu VS, Xu X, et al. ​Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis​. ​​Journal of the American Society of Nephrology. ​2014;​25​(5):​​905​-912​. ​doi:10.1681/ASN.2013070723. 
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  • 2014 | Journal Article | Research Paper
    ​ ​Charytan DM, Padera RF, Helfand AM, Zeisberg M, Xu X, Liu X, et al. ​Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease​. ​​International Journal of Cardiology. ​2014;​176​(1):​​99​-109​. ​doi:10.1016/j.ijcard.2014.06.062. 
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  • 2014 | Journal Article | Research Paper
    ​ ​Zeisberg M, Tampe B, LeBleu VS, Tampe D, Zeisberg EM, Kalluri R. ​Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure​. ​​American Journal Of Pathology. ​2014;​184​(10):​​2687​-2698​. ​doi:10.1016/j.ajpath.2014.06.014. 
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  • 2013 | Journal Article | Overview
    ​ ​Zeisberg EM, Zeisberg M. ​The role of promoter hypermethylation in fibroblast activation and fibrogenesis​. ​​Journal of Pathology. ​2013;​229​(2):​​264​-273​. ​doi:10.1002/path.4120. 
    ​Details  DOI  PMID  PMC  WoS 

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