A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

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​A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites​
Eisenberg-Bord, M.; Shai, N.; Schuldiner, M.   & Bohnert, M. ​ (2016) 
Developmental Cell39(4) pp. 395​-409​.​ DOI: https://doi.org/10.1016/j.devcel.2016.10.022 

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Authors
Eisenberg-Bord, Michal; Shai, Nadav; Schuldiner, Maya ; Bohnert, Maria 
Abstract
Membrane contact sites enable interorganelle communication by positioning organelles in close proximity using molecular "tethers." With a growing understanding of the importance of contact sites, the hunt for new contact sites and their tethers is in full swing. Determining just what is a tether has proven challenging. Here, we aim to delineate guidelines that define the prerequisites for categorizing a protein as a tether. Setting this gold standard now, while groups from different disciplines are beginning to explore membrane contact sites, will enable efficient cooperation in the growing field and help to realize a great collaborative opportunity to boost its development.
Issue Date
2016
Journal
Developmental Cell 
Project
SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente 
SFB 1190 | P11: Zuordnung zellulärer Kontaktstellen und deren Zusammenspiel 
Working Group
RG Bohnert (Lipid Droplet Kommunikation) 
RG Schuldiner (Functional Genomics of Organelles) 
ISSN
1534-5807
eISSN
1878-1551
Language
English

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