Resistance profiles of urinary tract infections in general practice - an observational study

2012 | journal article; research paper. A publication of Göttingen

Jump to: Cite & Linked | Documents & Media | Details | Version history

Cite this publication

​Resistance profiles of urinary tract infections in general practice - an observational study​
Schmiemann, G.; Gágyor, I. ; Hummers-Pradier, E.   & Bleidorn, J.​ (2012) 
BMC Urology12 art. 33​.​ DOI: 

Documents & Media


Published Version

Attribution 2.0 CC BY 2.0


Schmiemann, Guido; Gágyor, Ildikó ; Hummers-Pradier, Eva ; Bleidorn, Jutta
Background: Guideline recommendations on therapy in urinary tract infections are based on antibiotic resistance rates. Due to a lack of surveillance data, little is known about resistance rates in uncomplicated urinary tract infection (UTI) in general practice in Germany. In a prospective observational study, urine cultures of all women presenting with urinary tract infections in general practice were analysed. Resistance rates against antibiotics recommended in German guidelines on UTI are presented. Methods: In a prospective, multi-center observational study general practitioner included all female patients >= 18 years with clinically suspected urinary tract infection. Only patients receiving an antibiotic therapy within the last two weeks were excluded. Results: 40 practices recruited 191 female patients (mean age 52 years; range 18-96) with urinary tract infections. Main causative agent was Escherichia coli (79%) followed by Enterococcus faecalis (14%) and Klebsiella pneumoniae (7.3%). Susceptibiliy of E. coli as the main causative agent was highest against fosfomycin and nitrofurantoin, with low resistance rates of 4,5%; 2,2%. In 17,5%, E. coli was resistant to trimethoprim and in 8,5% to ciprofloxacin. Conclusions: Resistance rates of uropathogens from unselected patients in general practice differ from routinely collected laboratory data. These results can have an impact on antibiotic prescribing and treatment recommendations.
Issue Date
BMC Urology 
Institut für Allgemeinmedizin 



Social Media