Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy

2019-12 | journal article. A publication of Göttingen

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​Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy​
Hosseini, A. S. A. ; Uhlig, J.; Streit, U.; Uhlig, A.; Sprenger, T. ; Wedi, E.   & Ellenrieder, V.  et al.​ (2019) 
European Radiology29(12) pp. 6653​-6661​.​ DOI: https://doi.org/10.1007/s00330-019-06284-8 

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Hosseini, Ali Seif Amir ; Uhlig, Johannes; Streit, Ulrike; Uhlig, Annemarie; Sprenger, Thilo ; Wedi, Edris ; Ellenrieder, Volker ; Ghadimi, Michael B. ; Uecker, Martin ; Voit, Dirk; Frahm, Jens ; Lotz, Joachim ; Biggemann, Lorenz
Purpose To assess the diagnostic potential of real-time MRI for assessment of hiatal hernias in patients with GERD-like symptoms compared to endoscopy. Material and methods One hundred eight patients with GERD-like symptoms were included in this observational cohort study between 2015 and 2017. Real-time MRI was performed at 3.0 Tesla with temporal resolution of 40 ms, dynamically visualizing the esophageal transport of a pineapple juice bolus, its passage through the gastroesophageal junction, and functional responses during Valsalva maneuver. Hernia detection on MRI and endoscopy was calculated using contingency tables with diagnosis of hernia on either modality as reference. Results Of 108 patients, 107 underwent successful MRI without adverse events; 1 examination was aborted to inability to swallow pineapple juice in supine position. No perforation or acute bleeding occurred during endoscopy. Median examination time was 15 min. Eighty-five patients (79.4%) were diagnosed with hiatal hernia on either real-time MRI or endoscopy. Forty-six hernias were visible on both modalities. Seventeen hernias were evident exclusively on MRI, and 22 exclusively on endoscopy. Sixteen of the 63 MRI-detected hernias (25.4%) were detectable only during Valsalva maneuver, which were smaller compared to hernias at rest (median − 13.5 vs − 33.0 mm, p < 0.001). Diagnostic accuracy for hernia detection was comparable for MRI and endoscopy (sensitivity 74% vs 80%, p = 0.4223; specificity 100% vs 100%, p > 0.99).
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European Radiology 



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