Cite this publication
Reduction of potentially inappropriate medication in the elderly: design of a cluster-randomised controlled trial in German primary care practices (RIME)
Thiem, U.; Wilm, S.; Greiner, W.; Rudolf, H.; Trampisch, H.; Müller, C. & Theile, G. et al. (2020)
Therapeutic Advances in Drug Safety, 11. DOI: https://doi.org/10.1177/2042098620918459
- Thiem, Ulrich; Wilm, Stefan; Greiner, Wolfgang; Rudolf, Henrik; Trampisch, Hans–Joachim; Müller, Christiane ; Theile, Gudrun; Thürmann, Petra A.
- Potentially inappropriate medication (PIM) is considered to have potentially more harmful than beneficial health effects in elderly patients. A German example for a PIM list is the PRISCUS list that has been available since 2010. PIMs are associated with an increased risk of hospitalisation and adverse health outcomes. Furthermore, drug-drug interactions (DDI) may pose additional risks to patients. It is not yet clear how numbers of PIM and DDI can be reduced in community-dwelling seniors in primary care; nor is it clear whether patients would benefit from such deprescribing.
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- Therapeutic Advances in Drug Safety
- Institut für Allgemeinmedizin