Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease

2016 | Zeitschriftenartikel; Forschungsarbeit

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​Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease​
Burkhardt, D.; Bartosova, M.; Schaefer, B.; Grabe, N. ; Lahrmann, B.; Nasser, H. & Freise, C. u.a.​ (2016) 
PLoS One, 11(11) art. e0166050​.​ DOI: https://doi.org/10.1371/journal.pone.0166050 

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Autor(en)
Burkhardt, Dorothea; Bartosova, Maria; Schaefer, Betti; Grabe, Niels ; Lahrmann, Bernd; Nasser, Hamoud; Freise, Christian; Schneider, Axel; Lingnau, Anja; Degenhardt, Petra; Ranchin, Bruno; Sallay, Peter; Cerkauskiene, Rimante; Malina, Michal; Ariceta, Gema; Schmitt, Claus Peter; Querfeld, Uwe
Zusammenfassung
Endothelial dysfunction is an early manifestation of cardiovascular disease (CVD) and consistently observed in patients with chronic kidney disease (CKD). We hypothesized that CKD is associated with systemic damage to the microcirculation, preceding macrovascular pathology. To assess the degree of "uremic microangiopathy", we have measured microvascular density in biopsies of the omentum of children with CKD.
Erscheinungsdatum
2016
Zeitschrift
PLoS One 
eISSN
1932-6203
Sprache
Englisch

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