Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients
2015-05-20 | journal article; research paper
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Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients
Schrader, C. H; Kolb, M.; Zaoui, K.; Flechtenmacher, C.; Grabe, N. ; Weber, K.-J. & Hielscher, T. et al. (2015)
Molecular Cancer, 14(1) pp. 107. DOI: https://doi.org/10.1186/s12943-015-0381-6
Documents & Media
Details
- Authors
- Schrader, Carola H; Kolb, Markus; Zaoui, Karim; Flechtenmacher, Christa; Grabe, Niels ; Weber, Klaus-Josef; Hielscher, Thomas; Plinkert, Peter K.; Hess, Jochen
- Abstract
- Dysregulated expression of Kallikrein-related peptidase 6 (KLK6) is a common feature for many human malignancies and numerous studies evaluated KLK6 as a promising biomarker for early diagnosis or unfavorable prognosis. However, the expression of KLK6 in carcinomas derived from mucosal epithelia, including head and neck squamous cell carcinoma (HNSCC), and its mode of action has not been addressed so far.
- Issue Date
- 20-May-2015
- Journal
- Molecular Cancer
- ISSN
- 1476-4598
- Language
- English
