Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma
2017 | journal article; research paper
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Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma
Kreycy, N.; Gotzian, C.; Fleming, T.; Flechtenmacher, C.; Grabe, N. ; Plinkert, P. & Hess, J. et al. (2017)
BMC Cancer, 17(1) pp. 382. DOI: https://doi.org/10.1186/s12885-017-3367-5
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Details
- Authors
- Kreycy, Nele; Gotzian, Christiane; Fleming, Thomas; Flechtenmacher, Christa; Grabe, Niels ; Plinkert, Peter; Hess, Jochen; Zaoui, Karim
- Abstract
- Glyoxalase 1 is a key enzyme in the detoxification of reactive metabolites such as methylglyoxal and induced Glyoxalase 1 expression has been demonstrated for several human malignancies. However, the regulation and clinical relevance of Glyoxalase 1 in the context of head and neck squamous cell carcinoma has not been addressed so far.
- Issue Date
- 2017
- Journal
- BMC Cancer
- ISSN
- 1471-2407
- Language
- English
