Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines
2011-02-15 | journal article; research paper
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Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines
Halama, N.; Braun, M.; Kahlert, C.; Spille, A.; Quack, C.; Rahbari, N. & Koch, M. et al. (2011)
Clinical Cancer Research, 17(4) pp. 678-689. DOI: https://doi.org/10.1158/1078-0432.CCR-10-2173
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Details
- Authors
- Halama, Niels; Braun, Monika; Kahlert, Christoph; Spille, Anna; Quack, Christian; Rahbari, Nuh; Koch, Moritz; Weitz, Jürgen; Kloor, Matthias; Zoernig, Inka; Schirmacher, Peter; Brand, Karsten; Grabe, Niels ; Falk, Christine S.
- Abstract
- Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of intratumoral cytokines and chemokines in shaping the composition of the inflammatory lymphocytic infiltrate is also unclear.
- Issue Date
- 15-February-2011
- Journal
- Clinical Cancer Research
- ISSN
- 1078-0432
- eISSN
- 1557-3265
- Language
- English