Altered density, composition and microanatomical distribution of infiltrating immune cells in cutaneous squamous cell carcinoma of organ transplant recipients
2018 | journal article; research paper
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Altered density, composition and microanatomical distribution of infiltrating immune cells in cutaneous squamous cell carcinoma of organ transplant recipients
Strobel, S. B.; Safferling, K.; Lahrmann, B.; Hoffmann, J. H.; Enk, A. H.; Hadaschik, E. N. & Grabe, N. et al. (2018)
British Journal of Dermatology, 179(2) pp. 405-412. DOI: https://doi.org/10.1111/bjd.16477
Documents & Media
Details
- Authors
- Strobel, S. B.; Safferling, K.; Lahrmann, B.; Hoffmann, J. H.; Enk, A. H.; Hadaschik, E. N.; Grabe, Niels ; Lonsdorf, A. S.
- Abstract
- The inflammatory tumour microenvironment is crucial for effective tumour control, and long-term immunosuppression has been identified as a major risk factor for skin carcinogenesis. In solid organ transplant recipients (OTRs) undergoing long-term pharmacological immunosuppression, an increased incidence of cutaneous squamous cell carcinoma (SCC) and more aggressive tumour growth compared with immunocompetent patients has been reported.
- Issue Date
- 2018
- Journal
- British Journal of Dermatology
- ISSN
- 0007-0963
- eISSN
- 1365-2133
- Language
- English
