Bridging the scales: semantic integration of quantitative SBML in graphical multi-cellular models and simulations with EPISIM and COPASI
2013-01-15 | journal article; research paper
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Cite this publication
Bridging the scales: semantic integration of quantitative SBML in graphical multi-cellular models and simulations with EPISIM and COPASI
Sütterlin, T.; Kolb, C.; Dickhaus, H.; Jäger, D. & Grabe, N. (2013)
Bioinformatics, 29(2) pp. 223-229. DOI: https://doi.org/10.1093/bioinformatics/bts659
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Details
- Authors
- Sütterlin, Thomas; Kolb, Christoph; Dickhaus, Hartmut; Jäger, Dirk; Grabe, Niels
- Abstract
- Biological reality can in silico only be comprehensively represented in multi-scaled models. To this end, cell behavioural models addressing the multi-cellular level have to be semantically linked with mechanistic molecular models. These requirements have to be met by flexible software workflows solving the issues of different time scales, inter-model variable referencing and flexible sub-model embedding.
- Issue Date
- 15-January-2013
- Journal
- Bioinformatics
- ISSN
- 1367-4803; 1460-2059
- eISSN
- 1367-4811
- Language
- English
