Remote control of the heart and beyond
2022 | journal article; overview. A publication with affiliation to the University of Göttingen.
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Details
- Authors
- Zimmermann, Wolfram-Hubertus
- Abstract
- A resorbable closed-loop sensor-actuator implant can temporarily control heart rate
External and internal electrical pacing of the heart are fundamental interventions in patients with cardiovascular disease ( 1 ). Recently, wearables, such as the Apple Watch and Fitbit devices, have been introduced to the consumer market to monitor key bodily functions such as heart rate and rhythm, blood oxygenation, blood pressure, and body temperature ( 2 ). On page 1006 of this issue, Choi et al. ( 3 ) go beyond sensing by reporting a resorbable closed-loop sensor-actuator (see the figure), with the eventual aim of controlling heart function in patients with a postsurgical risk of bradycardia (slow heart rate). This technology is wireless, circumventing common shortcomings of implanted devices, such as drive-line infections or the need for surgical procedures to remove or replace, for example, pacemaker leads or batteries. The demonstrated cardiac application of this technology in rats, dogs, and ex vivo human heart preparations could improve outpatient surveillance, allowing for earlier release from the hospital and remote monitoring of patients living in medically underserved areas. - Issue Date
- 2022
- Journal
- Science
- Project
- EXC 2067: Multiscale Bioimaging
SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz
SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien
SFB 1002 | S01: In vivo und in vitro Krankheitsmodelle - Working Group
- RG Zimmermann (Engineered Human Myocardium)
- ISSN
- 0036-8075
- eISSN
- 1095-9203
- Language
- English