C1q is increased in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: A multi-cohort proteomics and immuno-assay validation study
2023-04-06 | journal article. A publication with affiliation to the University of Göttingen.
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C1q is increased in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: A multi-cohort proteomics and immuno-assay validation study
Chatterjee, M.; Özdemir, S.; Kunadt, M.; Koel-Simmelink, M.; Boiten, W.; Piepkorn, L. & Pham, T. V. et al. (2023)
Alzheimer's & Dementia: The journal of the Alzheimer's Association,. DOI: https://doi.org/10.1002/alz.13066
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Details
- Authors
- Chatterjee, Madhurima; Özdemir, Selcuk; Kunadt, Marcel; Koel-Simmelink, Marleen; Boiten, Walter; Piepkorn, Lars; Pham, Thang V.; Chiasserini, Davide; Piersma, Sander R.; Knol, Jaco C.; Möbius, Wiebke ; Mollenhauer, Brit; van der Flier, Wiesje M.; Jimenez, Connie R.; Teunissen, Charlotte E.; Jahn, Olaf; Schneider, Anja
- Abstract
- Extracellular vesicles (EVs) may propagate and modulate Alzheimer's disease (AD) pathology. We aimed to comprehensively characterize the proteome of cerebrospinal fluid (CSF) EVs to identify proteins and pathways altered in AD.
- Issue Date
- 6-April-2023
- Journal
- Alzheimer's & Dementia: The journal of the Alzheimer's Association
- Project
- EXC 2067: Multiscale Bioimaging
- Organization
- Klinik für Psychiatrie und Psychotherapie ; Max-Planck-Institut für Multidisziplinäre Naturwissenschaften ; Klinik für Neurologie
- Working Group
- RG Möbius
- ISSN
- 1552-5260
- eISSN
- 1552-5279
- Language
- English
