Innenarchitektur der Zellkraftwerke — Membranfalten in Hochauflösung

Abstract

Abstract Mitochondria are essential cellular organelles, which supply eukaryotic cells with the universal energy carrier adenosine triphosphate. These organelles feature a unique double-membrane architecture, which is formed by a smooth outer membrane and a highly folded inner membrane. Harnessing super-resolution light and electron microscopy, we investigate the role of MICOS, a large mitochondrial protein complex, in determining the complex folding of the inner membrane.