Pressure Drives Rapid Burst-Like Coordinated Cellular Motion from 3D Cancer Aggregates (Adv. Sci. 6/2022)
2022 | journal article. A publication with affiliation to the University of Göttingen.
Jump to: Cite & Linked | Documents & Media | Details | Version history
Cite this publication
Pressure Drives Rapid Burst-Like Coordinated Cellular Motion from 3D Cancer Aggregates (Adv. Sci. 6/2022)
Raghuraman, S.; Schubert, A.-S.; Bröker, S.; Jurado, A.; Müller, A.; Brandt, M. & Vos, B. E. et al. (2022)
Advanced Science, 9(6). DOI: https://doi.org/10.1002/advs.202270037
Documents & Media
Details
- Authors
- Raghuraman, Swetha; Schubert, Ann-Sophie; Bröker, Stephan; Jurado, Alejandro; Müller, Annika; Brandt, Matthias; Vos, Bart E.; Hofemeier, Arne D.; Abbasi, Fatemeh; Stehling, Martin; Wittkowski, Raphael; Ivaska, Johanna; Betz, Timo
- Abstract
- Coordinated Cell Motion In article number 2104808 by Swetha Raghuraman, Timo Betz, and co-workers, a novel migration phenomenon is presented wherein cancer cells burst out from tumor aggregates as an act of pressure release into the surrounding in-homogeneous soft extra-cellular matrix (ECM) made up of collagen. The pressure within tumor aggregates manifests due to cellular swelling, leading to a super-diffusive coordinated expulsion of cells within 12 hours, directed towards regions providing least mechanical resistance
- Issue Date
- 2022
- Journal
- Advanced Science
- ISSN
- 2198-3844
- Language
- English
- Notes
- graphical abstract
