Validation of a clinical score to determine the risk of acute renal failure after cardiac surgery
2010 | journal article. A publication with affiliation to the University of Göttingen.
Jump to: Cite & Linked | Documents & Media | Details | Version history
Cite this publication
Validation of a clinical score to determine the risk of acute renal failure after cardiac surgery
Heise, D.; Sundermann, D.; Braeuer, A. & Quintel, M. (2010)
European Journal of Cardio-Thoracic Surgery, 37(3) pp. 710-716. DOI: https://doi.org/10.1016/j.ejcts.2009.07.018
Documents & Media
Details
- Authors
- Heise, Daniel; Sundermann, Daniela; Braeuer, Anselm; Quintel, Michael
- Abstract
- Objective: Preoperative assessment of risk factors for postoperative acute renal failure (ARF) is a key point in the management of cardiac surgery patients. A reliable evaluation of individual risk permits the efficient application of prophylactic and therapeutic measures to patients with increased risk of ARE In 2005, Thakar published a scoring system to determine the ARF risk prior to surgery. The score allowed calculation of the incidence of postoperative ARF requiring dialysis (ARF-D) with a high level of precision. Methods: In order to examine the reproducibility of the results on different patient populations, we retrospectively applied the scoring system to 3508 cardiac surgery patients at the Goettingen University Hospital. Results: We found a qualitative correlation between the score value and ARF-D, but prognostic significance, when judged by the area under the receiver operating characteristic (ROC) curve, was considerably reduced. Also, the incidence of ARF-D in the Goettingen population was remarkably higher than the incidence shown by Thakar for patients with the same score. Conclusions: The correlation between score values and incidence of ARF-D shows that the Thakar score is qualitatively transferable to cardiac surgery patients from other centres. Though the score allows the discrimination between patients with higher or lower risks of ARF-D within the Goettingen collective, it was not suitable to estimate the real incidence of postoperative ARF-D with sufficient precision. (C) 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
- Issue Date
- 2010
- Status
- published
- Publisher
- Elsevier Science Bv
- Journal
- European Journal of Cardio-Thoracic Surgery
- ISSN
- 1010-7940