A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities
2011 | journal article. A publication with affiliation to the University of Göttingen.
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A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities
Zhang, H.; Wang, H.; Cui, H.; Li, Z.; Xie, Z.; Pu, Y. & Li, F. et al. (2011)
Marine Drugs, 9(9) pp. 1502-1509. DOI: https://doi.org/10.3390/md9091502
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Details
- Authors
- Zhang, Hongyu; Wang, H.; Cui, Hongli; Li, Zonggang; Xie, Zeping; Pu, Yang; Li, Fuchao; Qin, Song
- Abstract
- A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549.
- Issue Date
- 2011
- Status
- published
- Publisher
- Mdpi Ag
- Journal
- Marine Drugs
- ISSN
- 1660-3397
