Inflammation, demyelination, and degeneration - Recent insights from MS pathology
2011 | review. A publication with affiliation to the University of Göttingen.
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Inflammation, demyelination, and degeneration - Recent insights from MS pathology
Stadelmann-Nessler, C. ; Wegner, C.& Brueck, W. (2011)
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1812(2) pp. 275-282.
Elsevier Science Bv. DOI: https://doi.org/10.1016/j.bbadis.2010.07.007
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Details
- Authors
- Stadelmann-Nessler, Christine ; Wegner, Christiane; Brueck, Wolfgang
- Abstract
- Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system which responds to anti-inflammatory treatments in the early disease phase. However, the pathogenesis of the progressive disease phase is less well understood, and inflammatory as well as neurodegenerative mechanisms of tissue damage are currently being discussed. This review summarizes current knowledge on the interrelation between inflammation, demyelination, and neurodegeneration derived from the study of human autopsy and biopsy brain tissue and experimental models of MS. (C) 2010 Elsevier B.V. All rights reserved.
- Issue Date
- 2011
- Status
- published
- Publisher
- Elsevier Science Bv
- Journal
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- ISSN
- 0925-4439
