Purinergic activation of dorsal root ganglion neurones in vivo

2011 | journal article. A publication with affiliation to the University of Göttingen.

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​Purinergic activation of dorsal root ganglion neurones in vivo​
Dibaj, P.; Steffens, H.; Nadrigny, F.; Kirchhoff, F. & Schomburg, E. D.​ (2011) 
Neuroscience Letters487(1) pp. 107​-109​.​ DOI: https://doi.org/10.1016/j.neulet.2010.10.005 

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Authors
Dibaj, Payam; Steffens, Heinz; Nadrigny, Fabien; Kirchhoff, Frank; Schomburg, Eike D.
Abstract
Functional relevance of non-synaptic purinergic receptors on dorsal root ganglion cells was tested in vivo by the influence of ATP using 2P-LSM and Ca imaging. Within a few seconds after local application of ATP, neurones in dorsal root ganglion were activated indicated by an increase of their calcium signal. The signal reached its maximum within a few seconds and declined to control values after about 30s. Purinergic action seems to include non-synaptic cell-to-cell communication within dorsal root ganglia. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
Issue Date
2011
Status
published
Publisher
Elsevier Ireland Ltd
Journal
Neuroscience Letters 
ISSN
0304-3940
Sponsor
DFG [Scho 37/16]

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