Purinergic activation of dorsal root ganglion neurones in vivo
2011 | journal article. A publication with affiliation to the University of Göttingen.
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Purinergic activation of dorsal root ganglion neurones in vivo
Dibaj, P.; Steffens, H.; Nadrigny, F.; Kirchhoff, F. & Schomburg, E. D. (2011)
Neuroscience Letters, 487(1) pp. 107-109. DOI: https://doi.org/10.1016/j.neulet.2010.10.005
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Details
- Authors
- Dibaj, Payam; Steffens, Heinz; Nadrigny, Fabien; Kirchhoff, Frank; Schomburg, Eike D.
- Abstract
- Functional relevance of non-synaptic purinergic receptors on dorsal root ganglion cells was tested in vivo by the influence of ATP using 2P-LSM and Ca imaging. Within a few seconds after local application of ATP, neurones in dorsal root ganglion were activated indicated by an increase of their calcium signal. The signal reached its maximum within a few seconds and declined to control values after about 30s. Purinergic action seems to include non-synaptic cell-to-cell communication within dorsal root ganglia. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
- Issue Date
- 2011
- Status
- published
- Publisher
- Elsevier Ireland Ltd
- Journal
- Neuroscience Letters
- ISSN
- 0304-3940
- Sponsor
- DFG [Scho 37/16]